Search Results - "Balbo, Paul B"
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Mechanism of Poly(A) Polymerase: Structure of the Enzyme-MgATP-RNA Ternary Complex and Kinetic Analysis
Published in Structure (London) (01-09-2007)“…We report the 1.8 Å structure of yeast poly(A) polymerase (PAP) trapped in complex with ATP and a five residue poly(A) by mutation of the catalytically…”
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Proton transfer in the mechanism of polyadenylate polymerase
Published in Biochemical journal (01-06-2009)“…PAP (polyadenylate polymerase) is the template-independent RNA polymerase responsible for synthesis of the 3' poly(A) tails of mRNA. To investigate the role of…”
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3
Kinetic Mechanism of Active Site Assembly and Chemical Catalysis of DNA Polymerase β
Published in Biochemistry (Easton) (15-11-2011)“…It has been inferred from structural and computational studies that the mechanism of DNA polymerases involves subtle but important discrete steps that occur…”
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X-ray Crystallographic and Steady State Fluorescence Characterization of the Protein Dynamics of Yeast Polyadenylate Polymerase
Published in Journal of molecular biology (09-03-2007)“…Polyadenylate polymerase (PAP) catalyzes the synthesis of poly(A) tails on the 3′-end of pre-mRNA. PAP is composed of three domains: an N-terminal…”
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Campylobacter jejuni Cytolethal Distending Toxin Causes a G2-Phase Cell Cycle Block
Published in Infection and Immunity (01-05-1998)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Kinetic Studies of Yeast PolyA Polymerase Indicate an Induced Fit Mechanism for Nucleotide Specificity
Published in Biochemistry (Easton) (31-05-2005)“…Polyadenylate polymerase (PAP) catalyzes the synthesis of 3‘-polyadenylate tails onto mRNA. A comprehensive steady-state kinetic analysis of PAP was conducted…”
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Yersiniabactin from Yersinia pestis: biochemical characterization of the siderophore and its role in iron transport and regulation
Published in Microbiology (Society for General Microbiology) (01-05-1999)“…Department of Microbiology and Immunology, MS415 Medical Center, University of Kentucky, Lexington, KY 40536–0084, USA ABSTRACT A siderophore-dependent iron…”
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Spectrophotometric and Steady-State Kinetic Analysis of the Biosynthetic Arginine Decarboxylase of Yersinia pestis Utilizing Arginine Analogues as Inhibitors and Alternative Substrates
Published in Biochemistry (Easton) (30-12-2003)“…The PLP-dependent, biosynthetic arginine decarboxylase (ADC) of Yersinia pestis was investigated using steady-state kinetics employing structural analogues of…”
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Kinetics and mechanism of the acetyl-coenzyme A decarbonylase/synthase (ACDS) multienzyme complex of Methanosarcina thermophila
Published 01-01-2001“…Methanogenesis from acetate is an ecologically important process which accounts for 70% of all biological methane production. This process requires the…”
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Dissertation -
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Campylobacter jejuni Cytolethal Distending Toxin Causes a G 2 -Phase Cell Cycle Block
Published in Infection and immunity (01-05-1998)“…Cytolethal distending toxin (CDT) from the diarrheagenic bacterium Campylobacter jejuni was shown to cause a rapid and specific cell cycle arrest in HeLa and…”
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