Search Results - "Balasubramaniyan, Vairappan"

Increased systemic zonula occludens 1 associated with inflammation and independent biomarker in patients with hepatocellular carcinoma by Ram, Amit Kumar, Pottakat, Biju, Vairappan, Balasubramaniyan

“…Hepatocellular carcinoma (HCC) is a frequent type of primary liver cancer, and its prevalence is increasing worldwide. Indeed, the underlying molecular…”
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Deciphering the cross-talk between miRNA and tight junctions in hepatocellular carcinoma by Siva Bala Subramaniyan, Balasubramaniyan Vairappan

“…The most common type of liver cancer is hepatocellular carcinoma (HCC) causes a lower survival rate even after systemic treatment. Previous studies have shown…”
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Placental expression of striatin & endothelial nitric oxide synthase in women with & without pre-eclampsia by Viveka, M, Chaturvedula, Latha, Ram, Amit, Vairappan, Balasubramaniyan

“…Background & objectives: Striatin is a multi-domain scaffolding protein essential for activating endothelial nitric oxide synthase (eNOS). However, its role in…”
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Cut-off values and clinical efficacy of body roundness index and other novel anthropometric indices in identifying metabolic syndrome and its components among Southern-Indian adults by Endukuru, Chiranjeevi Kumar, Gaur, Girwar Singh, Dhanalakshmi, Yerrabelli, Sahoo, Jayaprakash, Vairappan, Balasubramaniyan

“…Context Abdominal obesity (AO) is a definitive link between cardiometabolic complications and metabolic syndrome (MetS). Many traditional and novel…”
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Role of pregnane X-receptor in regulating bacterial translocation in chronic liver diseases by Mohandas, Sundhar, Vairappan, Balasubramaniyan

“…Bacterial translocation(BT) has been impeccably implicated as a driving factor in the pathogenesis of a spectrum of chronic liver diseases(CLD). Scientific…”
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Comparison of the efficacy of 0.9% normal saline with balanced crystalloid (Plasmalyte) in maintaining the metabolic profile in head injury patients undergoing evacuation of acute subdural haematoma - A randomised controlled trial by Sakkanan, Naveen Vivek, Swaminathan, Srinivasan, Bidkar, Prasanna Udupi, Vairappan, Balasubramaniyan, Sathiaprabhu, A, Dey, Ankita

“…The choice of intravenous fluids is important in patients with traumatic brain injury (TBI), where large volumes may be required for resuscitation. Our study…”
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Correlation of Acute Inflammatory Markers with Oxidative Stress Markers in Patients with Chronic Pancreatitis: A Cross-sectional Study by Mohanan, Abhina, Pottakkat, BIJU, Vairappan, Balasubramaniyan, Gladwin, V

“…Introduction: Chronic Pancreatitis (CP) is a long-standing inflammation of the pancreas that presents as episodes of acute inflammation or chronic damage,…”
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Agreement between equation‐derived body fat estimator and bioelectrical impedance analysis for body fat measurement in middle‐aged southern Indians by Endukuru, Chiranjeevi Kumar, Gaur, Girwar Singh, Yerrabelli, Dhanalakshmi, Sahoo, Jayaprakash, Vairappan, Balasubramaniyan

“…Excess body fat (BF) contributes to metabolic syndrome (MetS). The Clínica Universidad de Navarra—Body Adiposity Estimator (CUN‐BAE) is an equation‐derived…”
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Liver Injury in COVID-19: A Direct Hit or Collateral Damage? by Vairappan, Balasubramaniyan, Wright, Gavin, Corrigal, Douglas, Ts, Ravikumar

“…SARS-CoV-2 is a novel coronavirus that has been identified, in December 2019, in Wuhan, China, and since it has become a worldwide pandemic, it has imposed…”
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Cut-off Values and Clinical Utility of Surrogate Markers for Insulin Resistance and Beta-Cell Function to Identify Metabolic Syndrome and Its Components among Southern Indian Adults by Endukuru, Chiranjeevi Kumar, Gaur, Girwar Singh, Yerrabelli, Dhanalakshmi, Sahoo, Jayaprakash, Vairappan, Balasubramaniyan

“…Insulin resistance (IR) is a collective clinical entity that exacerbates metabolic syndrome (MetS). As the gold-standard test to quantify IR involves…”
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Prevalence and determinants of sarcopenia in Indian patients with chronic kidney disease stage 3 & 4 by Dubey, Avinash Kumar, Sahoo, Jayaprakash, Vairappan, Balasubramaniyan, Parameswaran, Sreejith, Ps, Priyamvada

“…There is limited literature on the prevalence and determinants of sarcopenia in the Indian predialysis chronic kidney disease (CKD) population. The current…”
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Importance of Connexin-43 based gap junction in cirrhosis and acute-on-chronic liver failure by Balasubramaniyan, Vairappan, Dhar, Dipok Kumar, Warner, Anne E, Vivien Li, Wai-Yin, Amiri, Azin Farzan, Bright, Beverley, Mookerjee, Rajeshwar P, Davies, Nathan A, Becker, David L, Jalan, Rajiv

“…Graphical abstract Schematic representation of the adaptive and protective inducible expression of cx43 in chronic and acute-on-chronic liver injuries. Upon…”
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Response: Cut-off Values and Clinical Utility of Surrogate Markers for Insulin Resistance and Beta-Cell Function to Identify Metabolic Syndrome and Its Components among Southern Indian Adults (J Obes Metab Syndr 2020;29:281-91) by Endukuru, Chiranjeevi Kumar, Gaur, Girwar Singh, Yerrabelli, Dhanalakshmi, Sahoo, Jayaprakash, Vairappan, Balasubramaniyan

“…Background : One-anastomosis gastric bypass (OAGB) is a simpler procedure than Roux-en-Y gastric bypass (RYGB); however, biliary reflux can occur and impair…”
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Association between metabolic syndrome components and cardiac autonomic modulation in southern Indian adults with pre-metabolic syndrome: hyperglycemia is the major contributing factor by Endukuru Chiranjeevi Kumar, Girwar Singh Gaur, Dhanalakshmi Yerrabelli, Jayaprakash Sahoo

“…Metabolic syndrome (MetS) involves multi-factorial conditions linked to an elevated risk of type 2 diabetes mellitus and cardiovascular disease. Pre-metabolic…”
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Role of aquaporin-4 in the development of brain oedema in liver failure by Wright, Gavin, Soper, Robin, Brooks, Heather F, Stadlbauer, Vanessa, Vairappan, Balasubramaniyan, Davies, Nathan A, Andreola, Fausto, Hodges, Stephen, Moss, Raymond F, Davies, D. Ceri, Jalan, Rajiv

“…Background & Aims Liver failure is associated with progressive cytotoxic brain oedema (astrocyte swelling), which underlies hepatic encephalopathy (HE)…”
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Changes in the levels of comet parameters before and after fluoxetine therapy in major depression patients by Rajeev Panwar, M. Sivakumar, Vikas Menon, Balasubramaniyan Vairappan

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Changes in the levels of comet parameters before and after fluoxetine therapy in major depression patients by Panwar, Rajeev, Sivakumar, M., Menon, Vikas, Vairappan, Balasubramaniyan

“…Major depression belongs to mood disorders and characterized by worthlessness, no interest or happiness in any activity; lasting for atleast two weeks…”
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Endothelial dysfunction in cirrhosis: Role of inflammation and oxidative stress by Vairappan, Balasubramaniyan

“…This review describes the recent developments in the pathobiology of endothelial dysfunction (ED) in the context of cirrhosis with portal hypertension and…”
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Pregnane X receptor activation by its natural ligand Ginkgolide-A improves tight junction proteins expression and attenuates bacterial translocation in cirrhosis by Mohandas, Sundhar, Vairappan, Balasubramaniyan

“…Pregnane X receptor (PXR) is a ligand-activated transcription factor and nuclear receptor expressed ubiquitously along gut-liver-axis. Inflammatory bowel…”
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Ginkgolide-A attenuates bacterial translocation through activating PXR and improving antimicrobial peptide Reg 3A in experimental cirrhosis by Mohandas, Sundhar, Vairappan, Balasubramaniyan

“…Bacterial translocation (BT) is strongly associated with disease progression and poor outcome in cirrhotic patients. The role of Pregnane X receptor (PXR) in…”
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