Search Results - "Balasubramanian, Suresh K"

Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naïve Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis by Magnuson, William J, Lester-Coll, Nataniel H, Wu, Abraham J, Yang, T Jonathan, Lockney, Natalie A, Gerber, Naamit K, Beal, Kathryn, Amini, Arya, Patil, Tejas, Kavanagh, Brian D, Camidge, D Ross, Braunstein, Steven E, Boreta, Lauren C, Balasubramanian, Suresh K, Ahluwalia, Manmeet S, Rana, Niteshkumar G, Attia, Albert, Gettinger, Scott N, Contessa, Joseph N, Yu, James B, Chiang, Veronica L

“…Purpose Stereotactic radiosurgery (SRS), whole-brain radiotherapy (WBRT), and epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are…”
Get full text

Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats by Balasubramanian, Suresh K, Jittiwat, Jinatta, Manikandan, Jayapal, Ong, Choon-Nam, Yu, Liya E, Ong, Wei-Yi

“…Abstract Biodistribution of gold nanoparticles (AuNPs) in more than 25 organs were examined on 1 day, 1 week, 1 month and 2 months after a single intravenous…”
Get full text

The effect of primary particle size on biodistribution of inhaled gold nano-agglomerates by Balasubramanian, Suresh K, Poh, Kay-Wee, Ong, Choon-Nam, Kreyling, Wolfgang G, Ong, Wei-Yi, Yu, Liya E

“…Abstract Airborne engineered nanoparticles undergo agglomeration, and careful distinction must be made between primary and agglomerate size of particles, when…”
Get full text

Molecular patterns identify distinct subclasses of myeloid neoplasia by Kewan, Tariq, Durmaz, Arda, Bahaj, Waled, Gurnari, Carmelo, Terkawi, Laila, Awada, Hussein, Ogbue, Olisaemeka D., Ahmed, Ramsha, Pagliuca, Simona, Awada, Hassan, Kubota, Yasuo, Mori, Minako, Ponvilawan, Ben, Al-Share, Bayan, Patel, Bhumika J., Carraway, Hetty E., Scott, Jacob, Balasubramanian, Suresh K., Bat, Taha, Madanat, Yazan, Sekeres, Mikkael A., Haferlach, Torsten, Visconte, Valeria, Maciejewski, Jaroslaw P.

“…Genomic mutations drive the pathogenesis of myelodysplastic syndromes and acute myeloid leukemia. While morphological and clinical features have dominated the…”
Get full text

Author Correction: Molecular patterns identify distinct subclasses of myeloid neoplasia by Kewan, Tariq, Durmaz, Arda, Bahaj, Waled, Gurnari, Carmelo, Terkawi, Laila, Awada, Hussein, Ogbue, Olisaemeka D., Ahmed, Ramsha, Pagliuca, Simona, Awada, Hassan, Kubota, Yasuo, Mori, Minako, Ponvilawan, Ben, Al-Share, Bayan, Patel, Bhumika J., Carraway, Hetty E., Scott, Jacob, Balasubramanian, Suresh K., Bat, Taha, Madanat, Yazan, Sekeres, Mikkael A., Haferlach, Torsten, Visconte, Valeria, Maciejewski, Jaroslaw P.

Get full text

Novel scheme for defining the clinical implications of TP53 mutations in myeloid neoplasia by Bahaj, Waled, Kewan, Tariq, Gurnari, Carmelo, Durmaz, Arda, Ponvilawan, Ben, Pandit, Ishani, Kubota, Yasuo, Ogbue, Olisaemeka D, Zawit, Misam, Madanat, Yazan, Bat, Taha, Balasubramanian, Suresh K, Awada, Hussein, Ahmed, Ramsha, Mori, Minako, Meggendorfer, Manja, Haferlach, Torsten, Visconte, Valeria, Maciejewski, Jaroslaw P

“…TP53 mutations (TP53 ) occur in diverse genomic configurations. Particularly, biallelic inactivation is associated with poor overall survival in cancer…”
Get full text

Distinct clinical and biological implications of CUX1 in myeloid neoplasms by Aly, Mai, Ramdzan, Zubaidah M., Nagata, Yasunobu, Balasubramanian, Suresh K., Hosono, Naoko, Makishima, Hideki, Visconte, Valeria, Kuzmanovic, Teodora, Adema, Vera, Nazha, Aziz, Przychodzen, Bartlomiej P., Kerr, Cassandra M., Sekeres, Mikkael A., Abazeed, Mohamed E., Nepveu, Alain, Maciejewski, Jaroslaw P.

“…Somatic mutations of the CUT-like homeobox 1 (CUX1) gene (CUX1MT) can be found in myeloid neoplasms (MNs), in particular, in myelodysplastic syndromes (MDSs)…”
Get full text

Characterization, purification, and stability of gold nanoparticles by Balasubramanian, Suresh K, Yang, Liming, Yung, Lin-Yue L, Ong, Choon-Nam, Ong, Wei-Yi, Yu, Liya E

“…Abstract Impurities in the synthesized gold nanoparticle (AuNP) solution are systematically identified followed by determining an optimal purification process…”
Get full text

Clinical and molecular characteristics of extramedullary acute myeloid leukemias by Kewan, Tariq, Bahaj, Waled S., Gurnari, Carmelo, Ogbue, Olisaemeka D., Mukherjee, Sudipto, Advani, Anjali, Cook, James R., Rogers, Heesun J., Carraway, Hetty E., Balasubramanian, Suresh K., Visconte, Valeria, Maciejewski, Jaroslaw P.

Get full text

Clinical implications of somatic mutations in aplastic anemia and myelodysplastic syndrome in genomic age by Maciejewski, Jaroslaw P, Balasubramanian, Suresh K

“…Recent technological advances in genomics have led to the discovery of new somatic mutations and have brought deeper insights into clonal diversity. This…”
Get full text

Impact of EGFR mutation and ALK rearrangement on the outcomes of non–small cell lung cancer patients with brain metastasis by Balasubramanian, Suresh K, Sharma, Mayur, Venur, Vyshak A, Schmitt, Philipp, Kotecha, Rupesh, Chao, Samuel T, Suh, John H, Angelov, Lilyana, Mohammadi, Alireza M, Vogelbaum, Michael A, Barnett, Gene H, Jia, Xuefei, Pennell, Nathan A, Ahluwalia, Manmeet S

“…Abstract Background The impact of activating alterations in non–small cell lung cancer (NSCLC) (epidermal growth factor receptor [EGFR] mutation/anaplastic…”
Get full text

The evolution of paroxysmal nocturnal haemoglobinuria depends on intensity of immunosuppressive therapy by Bat, Taha, Abdelhamid, Omnia N., Balasubramanian, Suresh K., Mai, Aly, Radivoyevitch, Tomas, Clemente, Michael, Maciejewski, Jaroslaw P.

Get full text

Longitudinal experience with WHO Grade III (anaplastic) meningiomas at a single institution by Balasubramanian, Suresh K., Sharma, Mayur, Silva, Danilo, Karivedu, Vidhya, Schmitt, Philipp, Stevens, Glen H., Barnett, Gene H., Prayson, Richard A., Elson, Paul, Suh, John H., Murphy, Erin S., Chao, Samuel T.

“…To retrospectively analyze and assess the outcomes and prognostic factors in patients with anaplastic meningioma (AM) (WHO Grade III). Clinical data and…”
Get full text

Novel Therapeutic Targets for DNMT3A Mutant Myeloid Neoplasms by Adema, Vera, Balasubramanian, Suresh K., Hirsch, Cassandra M., Przychodzen, Bartlomiej P., Phillips, James G, Lindner, Daniel, Radivoyevitch, Tomas, Mukherjee, Sudipto, Nazha, Aziz, Carraway, Hetty E., Sole, Francesc, Sekeres, Mikkael A., Visconte, Valeria, Maciejewski, Jaroslaw P.

“…The DNMT3A mutations (DNMT3AMT) that occur in acute myeloid leukemia (AML) and Myelodysplastic syndromes (MDS) are either hypomorphic or inactivating,…”
Get full text

Functional and Biological Implications of CUX1 Mutations and Deletions in Myeloid Neoplasms by Aly, Mai, Ramdzan', Zubaidah M, Nagata, Yasunobu, Balasubramanian, Suresh K., Hosono, Naoko, Makishima, Hideki, Visconte, Valeria, Przychodzen, Bartlomiej P., Hirsch, Cassandra M., Sekeres, Mikkael A., Nepveu“, Alain, Maciejewski“, Jaroslaw

“…',“ authors equally contribute The CUX1 gene, located on 7q22.1, has been characterized genetically as a haplo-insufficient tumor suppressor gene. Somatic CUX1…”
Get full text

Activation of Autophagy in Models of SF3B1 Mutant MDS by Visconte, Valeria, Adema, Vera, Przychodzen, Bartlomiej P., Noe, Allison, Toth, Rachel, Hirbawi, Yasmine, Hirsch, Cassandra M., Khouri, Jack, LeMelle, Elise, Balasubramanian, Suresh K., Carraway, Hetty E., Lindner, Daniel, Advani, Anjali S., Rogers, Heesun J., Phillips, James G, Radivoyevitch, Tomas, Kelly, Kevin R, Nawrocki, Steffan T., Sekeres, Mikkael A., Maciejewski, Jaroslaw P., Carew, Jennifer

“…Background:SF3B1 is a key pre-mRNA splicing factor that is abundantly expressed in normal erythroid cells and whose mutation has been linked with high…”
Get full text