Search Results - "Balasubramani, Manimalha"
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New concepts in basement membrane biology
Published in The FEBS journal (01-12-2015)“…Basement membranes (BMs) are thin sheets of extracellular matrix that outline epithelia, muscle fibers, blood vessels and peripheral nerves. The current view…”
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Regulation of the autophagy protein LC3 by phosphorylation
Published in The Journal of cell biology (23-08-2010)“…Macroautophagy is a major catabolic pathway that impacts cell survival, differentiation, tumorigenesis, and neurodegeneration. Although bulk degradation…”
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Lysine 63-linked polyubiquitination is required for EGF receptor degradation
Published in Proceedings of the National Academy of Sciences - PNAS (24-09-2013)“…Ubiquitination mediates endocytosis and endosomal sorting of various signaling receptors, transporters, and channels. However, the relative importance of mono-…”
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Proteomic View of Basement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules
Published in Journal of proteome research (01-08-2014)“…Basement membranes (BMs) are extracellular matrix sheets comprising the laminins, type-IV collagens, nidogens, and the heparan sulfate proteoglycans, perlecan,…”
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Biomechanical properties of native basement membranes
Published in The FEBS journal (01-06-2007)“…Basement membranes are sheets of extracellular matrix that separate epithelia from connective tissues and outline muscle fibers and the endothelial lining of…”
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The bi-functional organization of human basement membranes
Published in PloS one (03-07-2013)“…The current basement membrane (BM) model proposes a single-layered extracellular matrix (ECM) sheet that is predominantly composed of laminins, collagen IVs…”
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ERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription: implications for Parkinson's disease
Published in Mitochondrion (01-07-2014)“…Mitochondrial transcription factor A (TFAM) regulates mitochondrial biogenesis, which is downregulated by extracellular signal-regulated protein kinases…”
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Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury
Published in Neurobiology of disease (01-02-2011)“…Abstract Cyclopentenone prostaglandins (CyPGs), such as 15-deoxy-Δ12,14 -prostaglandin J2 (15d-PGJ2 ), are active prostaglandin metabolites exerting a variety…”
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Molecular interactions in the retinal basement membrane system: A proteomic approach
Published in Matrix biology (01-07-2010)“…Basement membranes (BMs) are physiologically insoluble extracellular matrix sheets present in all multicellular organisms. They play an important role in…”
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Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress
Published in The EMBO journal (19-05-2010)“…Recent studies have shown a critical function for the ubiquitin‐proteasome system (UPS) in regulating the signalling network for DNA damage responses and DNA…”
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Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl
Published in Molecular cancer (22-07-2011)“…The proto-oncogene, c-Abl encodes a ubiquitously expressed tyrosine kinase that critically governs the cell death response induced by genotoxic agents such as…”
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Complex changes in the liver mitochondrial proteome of short chain acyl-CoA dehydrogenase deficient mice
Published in Molecular genetics and metabolism (01-05-2014)“…Short-chain acyl-CoA dehydrogenase (SCAD) deficiency is an autosomal recessive inborn error of metabolism that leads to the impaired mitochondrial fatty acid…”
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Temporary Disruption of the Retinal Basal Lamina and Its Effect on Retinal Histogenesis
Published in Developmental biology (01-10-2001)“…An experimental paradigm was devised to remove the retinal basal lamina for defined periods of development: the basal lamina was dissolved by injecting…”
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Expression of basal lamina protein mRNAs in the early embryonic chick eye
Published in Journal of comparative neurology (1911) (03-06-2002)“…Laminin, collagen IV, collagen XVIII, agrin, and nidogen are major protein constituents of the chick retinal basal lamina. To determine their sites of…”
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Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering
Published in Biomaterials (01-09-2013)“…Abstract Approximately 285 million people worldwide suffer from diabetes, with insulin supplementation as the most common treatment measure. Regenerative…”
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Extracellular Matrices of the Avian Ovarian Follicle
Published in The Journal of biological chemistry (01-05-2004)“…In egg-laying species, such as the chicken, the mode of transport of lipoprotein particles from the capillary plasma to endocytic receptors on the oocyte…”
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Sirtuin 3 (SIRT3) Protein Regulates Long-chain Acyl-CoA Dehydrogenase by Deacetylating Conserved Lysines Near the Active Site
Published in The Journal of biological chemistry (22-11-2013)“…Long-chain acyl-CoA dehydrogenase (LCAD) is a key mitochondrial fatty acid oxidation enzyme. We previously demonstrated increased LCAD lysine acetylation in…”
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Protein composition and biomechanical properties of in vivo-derived basement membranes
Published in Cell adhesion & migration (01-01-2013)“…Basement membranes (BMs) evolved together with the first metazoan species approximately 500 million years ago. Main functions of BMs are stabilizing epithelial…”
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In vitro Biocompatibility Test for Collagen-Based Dressings
Published in In vitro cellular & developmental biology. Animal (01-04-1997)Get full text
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