Search Results - "Balanzategui, A."

MYD88 L265P is a marker highly characteristic of, but not restricted to, Waldenström’s macroglobulinemia by Jiménez, C, Sebastián, E, Chillón, M C, Giraldo, P, Mariano Hernández, J, Escalante, F, González-López, T J, Aguilera, C, de Coca, A G, Murillo, I, Alcoceba, M, Balanzategui, A, Sarasquete, M E, Corral, R, Marín, L A, Paiva, B, Ocio, E M, Gutiérrez, N C, González, M, San Miguel, J F, García-Sanz, R

“…We evaluated the MYD88 L265P mutation in Waldenström’s macroglobulinemia (WM) and B-cell lymphoproliferative disorders by specific polymerase chain reaction…”
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Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma. A comparative analysis with flow cytometry by Puig, N, Sarasquete, M E, Balanzategui, A, Martínez, J, Paiva, B, García, H, Fumero, S, Jiménez, C, Alcoceba, M, Chillón, M C, Sebastián, E, Marín, L, Montalbán, M A, Mateos, M V, Oriol, A, Palomera, L, de la Rubia, J, Vidriales, M B, Bladé, J, Lahuerta, J J, González, M, Miguel, J F S, García-Sanz, R

“…We have analyzed the applicability, sensitivity and prognostic value of allele-specific oligonucleotide real-time quantitative PCR (ASO RQ-PCR) as a method for…”
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Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα by Bueno, C, Sardina, J L, Di Stefano, B, Romero-Moya, D, Muñoz-López, A, Ariza, L, Chillón, M C, Balanzategui, A, Castaño, J, Herreros, A, Fraga, M F, Fernández, A, Granada, I, Quintana-Bustamante, O, Segovia, J C, Nishimura, K, Ohtaka, M, Nakanishi, M, Graf, T, Menendez, P

“…B cells have been shown to be refractory to reprogramming and B-cell-derived induced pluripotent stem cells (iPSC) have only been generated from murine B cells…”
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MIPI53. A NEW PROGNOSTIC INDEX FOR MANTLE CELL LYMPHOMA by Boente, M. Bastos, Sánchez, M. Alcoceba, Bailón, A. Navarro, Herrera, A. Medina, Álvarez, M. García, Sarasquete, M. E. Alonso, Santos, C. Chillón, Echevarría, A. Balanzategui, Gómez, A. Antón, Niño, J., Loizaga, I. de la Torre, Bedera, N. H. Vidaña, Sánchez, R. Maldonado, Ruano, M. Hernández, Sánchez, S. M. Lucas, Villares, M. I. Sánchez, González, A. I. Sánchez, González de la Calle, V., Díaz, M. González, Sánchez, C. Jiménez, Sanz, R. García, García‐Sancho, A. Martín

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From Waldenström’s macroglobulinemia to aggressive diffuse large B-cell lymphoma: a whole-exome analysis of abnormalities leading to transformation by Jiménez, C, Alonso-Álvarez, S, Alcoceba, M, Ordóñez, G R, García-Álvarez, M, Prieto-Conde, M I, Chillón, M C, Balanzategui, A, Corral, R, Marín, L A, Gutiérrez, N C, Puig, N, Sarasquete, M E, González, M, García-Sanz, R

“…Transformation of Waldenström’s macroglobulinemia (WM) to diffuse large B-cell lymphoma (DLBCL) occurs in up to 10% of patients and is associated with an…”
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The predominant myeloma clone at diagnosis, CDR3 defined, is constantly detectable across all stages of disease evolution by Puig, N, Conde, I, Jiménez, C, Sarasquete, M E, Balanzategui, A, Alcoceba, M, Quintero, J, Chillón, M C, Sebastián, E, Corral, R, Marín, L, Gutiérrez, N C, Mateos, M-V, González-Díaz, M, San-Miguel, J F, García-Sanz, R

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TCRγδ+ large granular lymphocyte leukemias reflect the spectrum of normal antigen-selected TCRγδ+ T-cells by SANDBERG, Y, ALMEIDA, J, SAN MIGUEL, J. F, ORFAO, A, LANGERAK, A. W, GONZALEZ, M, LIMA, M, BARCENA, P, SZCZEPANSKI, T, VAN GASTEL-MOL, E. J, WIND, H, BALANZATEGUI, A, VAN DONGEN, J. J. M

“…T-cell large granular lymphocytes (LGL) proliferations range from reactive expansions of activated T cells to T-cell leukemias and show variable clinical…”
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Whole‐exome analysis of abnormalities leading to Waldenström's macroglobulinemia transformation into aggressive lymphoma by Alcoceba, M., Jiménez, C., Alonso‐Álvarez, S., Ordóñez, G.R., García‐Álvarez, M., Prieto‐Conde, M.I., Chillón, M.C., Balanzategui, A., Corral, R., Marín, L.A., Gutiérrez, N.C., Puig, N., Sarasquete, M.E., González, M., García‐Sanz, R.

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The relevance of preferentially expressed antigen of melanoma (PRAME) as a marker of disease activity and prognosis in acute promyelocytic leukemia by Santamaria, Carlos, Chillon, Maria Carmen, Garcia-Sanz, Ramon, Balanzategui, Ana, Sarasquete, Maria Eugenia, Alcoceba, Miguel, Ramos, Fernando, Bernal, Teresa, Queizan, Jose Antonio, Penarrubia, Maria Jesus, Giraldo, Pilar, San Miguel, Jesus F, Gonzalez, Marcos

“…1 Hospital Universitario, Salamanca 2 Centro de Investigación del Cáncer-IBMCC (USAL-CSIC) of Salamanca 3 Complejo Hospitalario de Leon 4 Hospital Central de…”
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Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma by Armellini, A., Sarasquete, M. E., García‐Sanz, R., Chillón, M. C., Balanzategui, A., Alcoceba, M., Fuertes, M., López, R., Hernández, J. M., Fernández‐Calvo, J., Sierra, M., Megido, M., Orfão, A., Gutiérrez, N. C., González, M., San Miguel, J. F.

“…Summary RAN, ZHX2 and RCBTB2 (CHC1L) expression was evaluated by quantitative real time reverse transcription polymerase chain reaction in plasma cells from 85…”
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Molecular and flow cytometry characterization during the follow-up of three simultaneous lymphoproliferative disorders: hairy cell leukemia, monoclonal B-cell lymphocytosis, and CD4(++) /CD8(+/- dim) T-large granular lymphocytosis--a case report by Garrido, P, Jiménez, P, Sánchez, C, Valero, F, Balanzategui, A, Almagro, M, López, P, de Pablos, J M, Navarro, P, Cabrera, A, González, M, Jurado, M, Ruiz-Cabello, F

“…The simultaneous diagnosis of hairy cell leukemia and monoclonal B-cell lymphocytosis with the characteristics of "indolent" chronic lymphocytic leukemia is…”
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De novo methylation of tumor suppressor gene p16/INK4a is a frequent finding in multiple myeloma patients at diagnosis by GONZALEZ, M, MATEOS, M. V, GARCIA-SANZ, R, BALANZATEGUI, A, LOPEZ-PEREZ, R, CHILLON, M. C, GONZALEZ, D, ALAEJOS, I, MIGUEL, J. S

“…The p16 gene competes with cyclin D for binding to CDK4/CDK6 and therefore inhibits CDK4/6 complex kinase activity, resulting in dephosphorylation of pRb and…”
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Molecular and flow cytometry characterization during the follow‐up of three simultaneous lymphoproliferative disorders: Hairy cell leukemia, monoclonal B‐cell lymphocytosis, and CD4++/CD8+/−dim T‐large granular lymphocytosis—A case report by Garrido, P., Jiménez, P., Sánchez, C., Valero, F., Balanzategui, A., Almagro, M., López, P., de Pablos, J. M., Navarro, P., Cabrera, A., González, M., Jurado, M., Ruiz‐Cabello, F.

“…The simultaneous diagnosis of hairy cell leukemia and monoclonal B‐cell lymphocytosis with the characteristics of “indolent” chronic lymphocytic leukemia is…”
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Incomplete DJH rearrangements of the IgH gene are frequent in multiple myeloma patients: immunobiological characteristics and clinical implications by GONZALEZ, D, BALANZATEGUI, A, GARCIA-SANZ, R, GUTIERREZ, N, SEABRA, C, VAN DONGEN, J. J. M, GONZALEZ, M, SAN MIGUEL, J. F

“…DH-JH rearrangements of the Ig heavy-chain gene (IGH) occur early during B-cell development. Consequently, they are detected in precursor-B-cell acute…”
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Incomplete DJH rearrangements as a novel tumor target for minimal residual disease quantitation in multiple myeloma using real-time PCR by GONZALEZ, D, GONZALEZ, M, ALONSO, M. E, LOPEZ-PEREZ, R, BALANZATEGUI, A, CHILLON, M. C, SILVA, M, GARCIA-SANZ, R, SAN MIGUEL, J. F

“…The hypervariable regions of immunoglobulin heavy-chain (IgH) rearrangements provide a specific tumor marker in multiple myeloma (MM). Recently, real-time PCR…”
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Hyperhomocysteinemia is a risk factor of recurrent coronary event in young patients irrespective to the MTHFR C677T polymorphism by Gonzalez-Porras, J.R, Martin-Herrero, F, Garcia-Sanz, R, Lopez, M.L, Balanzategui, A, Mateos, M.V, Pavon, P, Gonzalez, M, Alberca, I, San Miguel, J.F

“…Abstract Despite the well-known pro-coagulant effect of hyperhomocysteinemia, data is limited regarding the result on recurrent coronary event (RCE) in young…”
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Low frequency of the TEL/AML1 fusion gene in acute lymphoblastic leukaemia in Spain by García-Sanz, R, Alaejos, I, Orfão, A, Rasillo, A, Chillón, M C, Tabernero, M D, Mateos, M V, López-Pérez, R, González, D, Balanzategui, A, González, M, San Miguel, J F, Bortolucci, A

“…We report on a series of Spanish patients with acute lymphoblastic leukaemia in whom the t(12;21) [TEL/AML1] translocation could not be identified with two…”
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Gene scanning of VDJH-amplified segments is a clinically relevant technique to detect contaminating tumor cells in the apheresis products of multiple myeloma patients undergoing autologous peripheral blood stem cell transplantation by LOPEZ-PEREZ, R, GARCIA-SANZ, R, GONZALEZ, M, SAN MIGUEL, J. F, GONZALEZ, D, BALANZATEGUI, A, CHILLON, M. C, ALAEJOS, I, MATEOS, M. V, CABALLERO, M. D, CORRAL, M, ORFAO, A

“…Contaminating tumour cells in apheresis products have proved to influence the outcome of patients with multiple myeloma (MM) undergoing autologous stem cell…”
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The detection of contaminating clonal cells in apheresis products is related to response and outcome in multiple myeloma undergoing autologous peripheral blood stem cell transplantation by LOPEZ-PEREZ, R, GARCIA-SANZ, R, GONZALEZ, M, MIGUEL, J. F. S, GONZALEZ, D, BALANZATEGUI, A, CHILLON, M. C, ALAEJOS, I, MATEOS, M. V, CABALLERO, M. D, MATEO, G, NIETO, M. J

“…In the present paper, we report on the use of the heteroduplex PCR technique to detect the presence of clonally rearranged VDJ segments of the heavy chain…”
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Molecular characterization of acute myeloblastic leukemia according to the new WHO classification: a different distribution in Central-West Spain by Chillon, CM, Garcia-Sanz, R, Balanzategui, A, Ramos, F, Fernandez-Calvo, J, Rodriguez, MJ, Rodriguez-Salazar, MI, Corrales, A, Calmuntia, MJ, Orfao, A, Gonzalez, M, San Miguel, JF

“…Department of Hematology, University Hospital of Salamanca, Paseo de San Vicente, 58-182, Salamanca 37007, Spain. BACKGROUND AND OBJECTIVES: Molecular analysis…”
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