Endoscopic Injection Therapy in Bleeding Peptic Ulcers. Low Mortality in a High Risk Population
Endoscoric injection therapy was performed in 341 patients consecutively admitted with a bleeding peptic ulcer at high risk of further hemorrhage, assessed by the presence of active arterial bleeding or a nonbleeding visible vessel at emergency endoscopy. Initial hemostasis was achieved in 111 of 11...
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| Published in: | Canadian journal of gastroenterology Vol. 6; no. 5; pp. 265 - 268 |
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| Main Authors: | , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Hindawi Limited
1992
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| Online Access: | Get full text |
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| Summary: | Endoscoric injection therapy was performed in 341 patients consecutively admitted with a bleeding peptic ulcer at high risk of further hemorrhage, assessed by the presence of active arterial bleeding or a nonbleeding visible vessel at emergency endoscopy. Initial hemostasis was achieved in 111 of 119 actively bleeding patients (93%). Rebleeding ocurred in 75 cases (23%), at a mean interval of 53±52 h. A second emergency injection was a ttempted in 36 therapeutic failures, and was successful in 20 (55%). Emergency surgery was finally required in 52 patients (15%). Overall mortality was 4.9%. Major complications occurred in four patients (1.2%) (two perforations and two aspiration pneumonia); therefore, injection therapy is an effective and simple method for treating bleeding ulcers, achieving the initial control of hemorrhage in a majority of cases although the rate of further hemorrhage is not negligible and complications are not irrelevant. |
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| ISSN: | 0835-7900 |
| DOI: | 10.1155/1992/416485 |