Search Results - "Balandrán, Juan Carlos"
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Evidence of lateral transmission of aggressive features between different types of breast cancer cells
Published in International journal of oncology (01-11-2017)“…Breast cancer (BrC) is a major public health problem worldwide. The intra-tumoral heterogeneity and tumor cell plasticity importantly contribute to disease…”
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The Role of miRNAs in Childhood Acute Lymphoblastic Leukemia Relapse and the Associated Molecular Mechanisms
Published in International journal of molecular sciences (21-12-2023)“…Acute lymphoblastic leukemia (ALL) is the most common cancer in children worldwide. Although ALL patients' overall survival rates in wealthy countries…”
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3
Patient-Derived Bone Marrow Spheroids Reveal Leukemia-Initiating Cells Supported by Mesenchymal Hypoxic Niches in Pediatric B-ALL
Published in Frontiers in immunology (19-10-2021)“…B-cell acute lymphoblastic leukemia (B-ALL) results from the expansion of malignant lymphoid precursors within the bone marrow (BM), where hematopoietic niches…”
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Pro-inflammatory-Related Loss of CXCL12 Niche Promotes Acute Lymphoblastic Leukemic Progression at the Expense of Normal Lymphopoiesis
Published in Frontiers in immunology (05-01-2017)“…Pediatric oncology, notably childhood acute lymphoblastic leukemia (ALL), is currently one of the health-leading concerns worldwide and a biomedical priority…”
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VCAM1 confers innate immune tolerance on haematopoietic and leukaemic stem cells
Published in Nature cell biology (01-03-2022)Get full text
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Poor Prognosis Biomolecular Factors Are Highly Frequent in Childhood Acute Leukemias From Oaxaca, Mexico
Published in Technology in cancer research & treatment (01-01-2020)“…Objective: To investigate the cellular and molecular epidemiology of acute leukemias in vulnerable populations of children and adolescents in Oaxaca de Juarez,…”
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B lymphocyte ontogeny
Published in Revista alergia Mexico (Tecamachalco, Pueblo, Mexico : 1993) (01-01-2016)“…The B cell development from hematopoietic stem cells is a continuous and highly regulated process where multiple differentiation potentials are gradually lost…”
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The Role of Inflammation in the Initiation and Progression of Myeloid Neoplasms
Published in Blood cancer discovery (05-07-2023)“…Myeloid malignancies are devastating hematologic cancers with limited therapeutic options. Inflammation is emerging as a novel driver of myeloid malignancy,…”
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Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia
Published in Nature medicine (01-08-2018)“…Cellular transformation is accompanied by extensive rewiring of many biological processes leading to augmented levels of distinct types of cellular stress,…”
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10
VCAM1 confers innate immune tolerance on haematopoietic and leukaemic stem cells
Published in Nature cell biology (01-03-2022)“…Haematopoietic stem cells (HSCs) home to the bone marrow via, in part, interactions with vascular cell adhesion molecule-1 (VCAM1) 1 – 3 . Once in the bone…”
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Childhood Acute Leukemias in Developing Nations: Successes and Challenges
Published in Current oncology reports (01-05-2021)“…Purpose of Review Acute leukemias represent a tremendous threat to public health around the globe and the main cause of death due to disease in scholar age…”
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TLR Stimulation of Bone Marrow Lymphoid Precursors from Childhood Acute Leukemia Modifies Their Differentiation Potentials
Published in BioMed research international (01-01-2013)“…Acute leukemias are the most frequent childhood malignancies worldwide and remain a leading cause of morbidity and mortality of relapsed patients. While…”
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High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse
Published in Leukemia (01-06-2019)“…Cancer is a major cause of death in children worldwide, with B-lineage cell acute lymphoblastic leukemia (B-ALL) being the most frequent childhood malignancy…”
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Acute lymphoblastic leukemia‐secreted miRNAs induce a proinflammatory microenvironment and promote the activation of hematopoietic progenitors
Published in Journal of leukocyte biology (01-07-2022)“…Leukemogenesis is proposed to result from the continuous interplay between inducive bone marrow (BM) microenvironments and malignant precursor cells. Recent…”
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CRTAM+ NK cells endowed with suppressor properties arise in leukemic bone marrow
Published in Journal of leukocyte biology (01-05-2019)“…Due to their increasing rates of morbidity and mortality, childhood malignancies are considered a global health priority, with acute lymphoblastic leukemias…”
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Chronic Comorbidities in Middle Aged Patients Contribute to Ineffective Emergency Hematopoiesis in Covid-19 Fatal Outcomes
Published in Archives of medical research (01-04-2023)“…Mexico is among the countries with the highest estimated excess mortality rates due to the COVID–19 pandemic, with more than half of reported deaths occurring…”
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Implementation of a roadmap for the comprehensive diagnosis, follow-up, and research of childhood leukemias in vulnerable regions of Mexico: results from the PRONAII Strategy
Published in Frontiers in oncology (03-04-2024)“…The main objective of the National Project for Research and Incidence of Childhood Leukemias is to reduce early mortality rates for these neoplasms in the…”
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Serum Th17 and TNF-α distinguish between patients with occult hepatitis B infection, chronic hepatitis B infection and healthy individuals
Published in European cytokine network (01-06-2021)“…Chronic hepatitis B (CHB) is classified into five phases based on virus-host interactions: immune tolerance, immune clearance, inactive carrier state, reactive…”
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Subclassification of B-acute lymphoblastic leukemia according to age, immunophenotype and microenvironment, predicts MRD risk in Mexican children from vulnerable regions
Published in Frontiers in oncology (2023)“…The decisive key to disease-free survival in B-cell precursor acute lymphoblastic leukemia in children, is the combination of diagnostic timeliness and…”
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Analysis of Normal Hematopoietic Stem and Progenitor Cell Contents in Childhood Acute Leukemia Bone Marrow
Published in Archives of medical research (01-11-2016)“…Background and Aims Childhood acute leukemias (AL) are characterized by the excessive production of malignant precursor cells at the expense of effective blood…”
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