Search Results - "Balakrishnan, Kannan"
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An in-silico approach to identify the potential hot spots in SARS-CoV-2 spike RBD to block the interaction with ACE2 receptor
Published in Journal of biomolecular structure & dynamics (02-11-2022)“…A novel acute viral pneumonia induced by SARS-CoV-2 exploded at the end of 2019, causing a severe medical and economic crisis. For developing specific…”
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SignQuiz: A Quiz Based Tool for Learning Fingerspelled Signs in Indian Sign Language Using ASLR
Published in IEEE access (2019)“…Sign Language is one of the media of communication for deaf people. One should learn sign language to interact with them. Learning usually takes place in peer…”
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Potential inhibition of SARS-CoV-2 infection and its mutation with the novel geldanamycin analogue: Ignaciomycin
Published in Arabian journal of chemistry (01-02-2024)“…The impact of novel coronavirus (SARS-CoV-2) is very high; its mutant variants provide a higher transmission rate. Due to many mutations in the…”
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Application of Crowdsourcing in User Experience collection – a case study of Malayalam mobile applications
Published in Rajagiri Management Journal (01-01-2024)“…Purpose This paper aims to prove the following hypothesis Problem Statement: HYPOTHESIS (1) User Experience collection of mobile applications can be done using…”
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Tough Way In, Tough Way Out: The Complex Interplay of Host and Viral Factors in Nucleocytoplasmic Trafficking during HIV-1 Infection
Published in Viruses (01-11-2022)“…Human immunodeficiency virus-1 (HIV-1) is a retrovirus that integrates its reverse-transcribed genome as proviral DNA into the host genome to establish a…”
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Rewiring of Metabolic Network in Mycobacterium tuberculosis During Adaptation to Different Stresses
Published in Frontiers in microbiology (29-10-2019)“…Metabolic adaptation of Mycobacterium tuberculosis ( M. tuberculosis ) to microbicidal intracellular environment of host macrophages is fundamental to its…”
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Loop 1 of APOBEC3C Regulates its Antiviral Activity against HIV-1
Published in Journal of molecular biology (20-11-2020)“…[Display omitted] •Loop 1 residues in primate APOBEC3C and closely related A3s are under positive selection.•A3C in monkeys and apes replaced the highly active…”
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ATP competes with PIP2 for binding to gelsolin
Published in PloS one (07-08-2018)“…Gelsolin is a severing and capping protein that targets filamentous actin and regulates filament lengths near plasma membranes, contributing to cell movement…”
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Molecular Diffusion Measurement in Lipid Bilayers over Wide Concentration Ranges: A Comparative Study
Published in Chemphyschem (04-04-2008)“…Molecular diffusion in biological membranes is a determining factor in cell signaling and cell function. In the past few decades, three main fluorescence…”
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Encapsidation of Staufen-2 Enhances Infectivity of HIV-1
Published in Viruses (08-12-2021)“…Staufen, the RNA-binding family of proteins, affects various steps in the Human Immuno-Deficiency Virus (HIV-1) replication cycle. While our previous study…”
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Multiclass Image Segmentation using Deep Residual Encoder-Decoder Models in Highly Turbid Underwater Ambiances
Published in International journal of mathematical, engineering and management sciences (01-12-2024)“…Underwater environments, especially the coral reefs, are the habitat of many critically endangered species. Extensive monitoring of these aquatic ecosystems is…”
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Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
Published in Nature structural & molecular biology (01-04-2010)“…Capping protein (CP) regulates actin dynamics through binding to the barbed ends of actin filaments. Structural analysis of the CP interaction motifs from…”
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13
Betweenness centrality in Cartesian product of graphs
Published in AKCE international journal of graphs and combinatorics (02-01-2020)“…Betweenness centrality is a widely used measure in various graphs and it has a pivotal role in the analysis of complex networks. It measures the potential or…”
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Ca²⁺ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2009)“…Gelsolin consists of six homologous domains (G1-G6), each containing a conserved Ca-binding site. Occupation of a subset of these sites enables gelsolin to…”
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Human protein Staufen-2 promotes HIV-1 proliferation by positively regulating RNA export activity of viral protein Rev
Published in Retrovirology (13-02-2014)“…The export of intron containing viral RNAs from the nucleus to the cytoplasm is an essential step in the life cycle of Human Immunodeficiency Virus-1 (HIV-1)…”
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Spatially Resolved Total Internal Reflection Fluorescence Correlation Microscopy Using an Electron Multiplying Charge-Coupled Device Camera
Published in Analytical chemistry (Washington) (15-06-2007)“…A spatially resolved total internal reflection fluorescence correlation microscopy (TIR-FCM) system is constructed with an electron multiplying charge-coupled…”
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Mycobacterial and HIV infections up-regulated human zinc finger protein 134, a novel positive regulator of HIV-1 LTR activity and viral propagation
Published in PloS one (21-08-2014)“…Concurrent occurrence of HIV and Tuberculosis (TB) infections influence the cellular environment of the host for synergistic existence. An elementary approach…”
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Electron Multiplying Charge-Coupled Device Camera Based Fluorescence Correlation Spectroscopy
Published in Analytical chemistry (Washington) (15-05-2006)“…A fluorescence correlation spectroscopy (FCS) setup is built with an electron multiplying charge-coupled device camera. Although the instrument has a limited…”
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19
crystal structure of the C-terminus of adseverin reveals the actin-binding interface
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2009)“…Adseverin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. Adseverin comprises 6 homologous domains (A1-A6),…”
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Vision loss in Guillain-Barre syndrome: Is it a complication of Guillain-Barre syndrome or just a coincidence?
Published in Journal of ophthalmic & vision research (01-07-2016)Get full text
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