Search Results - "Balaikaite, Arune"
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The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry
Published in Nature communications (29-05-2019)“…The UbiX-UbiD enzymes are widespread in microbes, acting in concert to decarboxylate alpha-beta unsaturated carboxylic acids using a highly modified flavin…”
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Journal Article -
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Ferulic Acid Decarboxylase Controls Oxidative Maturation of the Prenylated Flavin Mononucleotide Cofactor
Published in ACS chemical biology (18-09-2020)“…Prenylated flavin mononucleotide (prFMN) is a recently discovered modified flavin cofactor containing an additional nonaromatic ring, connected to the N5 and…”
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Journal Article -
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Janus of the Flavin World : A Study of prFMN Cofactor Maturation and Catalysis
Published 01-01-2021“…Flavins are an old family of cofactors, first discovered almost 150 years ago, in 1879. But even up to this day they do still bring surprises, revealing new…”
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Dissertation -
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Biochemistry of prenylated-FMN enzymes
Published in The Enzymes (2020)“…The reversible (de)carboxylation of unsaturated carboxylic acids is carried out by the UbiX-UbiD system, ubiquitously present in microbes. The biochemical…”
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Journal Article -
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Heterologous production, reconstitution and EPR spectroscopic analysis of prFMN dependent enzymes
Published in Methods in enzymology (2019)“…The recent discovery of the prenylated FMN (prFMN) cofactor has led to a renewed interest in the prFMN-dependent UbiD family of enzymes. The latter catalyses…”
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Journal Article