Search Results - "Balacco, Dario"

The m 6 A Writer: Rise of a Machine for Growing Tasks by Balacco, Dario L, Soller, Matthias

“…The central dogma of molecular biology introduced by Crick describes a linear flow of information from DNA to mRNA to protein. Since then it has become evident…”
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Iron-mediated epigenetic activation of NRF2 targets by Horniblow, Richard D, Pathak, Prachi, Balacco, Dario L, Acharjee, Animesh, Lles, Eva, Gkoutos, Georgios, Beggs, Andrew D, Tselepis, Chris

“…The toxic effects of excess dietary iron within the colonic lumen are well documented, particularly in the context of Inflammatory Bowel Disease (IBD) and…”
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Repeated exposure of nosocomial pathogens to silver does not select for silver resistance but does impact ciprofloxacin susceptibility by Villapún, Victor M., Balacco, Dario L., Webber, Mark A., Hall, Thomas, Lowther, Morgan, Addison, Owen, Kuehne, Sarah A., Grover, Liam M., Cox, Sophie C.

“…The rise of antimicrobial resistant bacteria coupled with a void in antibiotic development marks Antimicrobial Resistance as one of the biggest current threats…”
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Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex by Winkler, G Sebastiaan, Balacco, Dario L

“…The shortening of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a pivotal step in the regulation of gene expression in eukaryotic cells…”
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Fusobacterium nucleatum Subspecies Differ in Biofilm Forming Ability in vitro by Muchova, Maria, Balacco, Dario L, Grant, Melissa M, Chapple, Iain L C, Kuehne, Sarah A, Hirschfeld, Josefine

“…Development of dysbiosis in complex multispecies bacterial biofilms forming on teeth, known as dental plaque, is one of the factors causing periodontitis. ( )…”
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PDZD8 is not the 'functional ortholog' of Mmm1, it is a paralog [version 1; peer review: 2 approved] by Wideman, Jeremy G, Balacco, Dario L, Fieblinger, Tim, Richards, Thomas A

“…Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers…”
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Synthesis and Antibacterial Evaluation of New Pyrazolo[3,4- d ]pyrimidines Kinase Inhibitors by Greco, Chiara, Catania, Rosa, Balacco, Dario Leonardo, Taresco, Vincenzo, Musumeci, Francesca, Alexander, Cameron, Huett, Alan, Schenone, Silvia

“…Pyrazolo[3,4- ]pyrimidines represent an important class of heterocyclic compounds well-known for their anticancer activity exerted by the inhibition of…”
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The m6A Writer: Rise of a Machine for Growing Tasks by Balacco, Dario L, Soller, Matthias

“…The central dogma of molecular biology introduced by Crick describes a linear flow of information from DNA to mRNA to protein. Since then it has become evident…”
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Is there microbial dysbiosis in CTCL? A pilot study by Peterknecht, Elizabeth, Molloy, Kevin, Morsia, Erika, Silva, Joana, Zottarelli, Francesca, Balacco, Dario, Kuehne, Sarah, Chapple, Iain, Beggs, Andrew, Scarisbrick, Julia

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BG05 Artificial intelligence prediction of splice site mutation consequences in junctional epidermolysis bullosa: signposts to severity by Wen, David, Balacco, Dario, Hunjan, Manrup, Bardhan, Ajoy, Harper, Natasha, Ogboli, Malobi, Ozoemena, Linda, Liu, Lu, Chapple, Iain, Heagerty, Adrian

“…Over one-fifth of disease-causing mutations in junctional epidermolysis bullosa (JEB) are splice site variants. These affect pre-mRNA splicing through the…”
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Are existing validated severity scores for epidermolysis bullosa reflective of the burden of disease in patients with epidermolysis bullosa simplex? by Hunjan, Manrup K, Bardhan, Ajoy, Zuzarte, Louise, Balacco, Dario Leonardo, Harper, Natasha, Heagerty, Adrian

“…Our study demonstrates that severity scores do not correlate well with the impact that localized epidermolysis bullosa simplex (EBS) has on quality of life…”
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IgA nephropathy in adults with epidermolysis bullosa by Hunjan, Manrup K, Bardhan, Ajoy, Harper, Natasha, Balacco, Dario Leonardo, Langman, Gerald, Suresh, Vijay, Heagerty, Adrian

“…Epidermolysis bullosa (EB) is a devastating genetic condition caused by mutations in genes that give rise to aberrant proteins. There are 16 different such…”
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Analysis of the ccr4-not deadenylase complex: a biochemical and computational approach by Balacco, Dario Leonardo

“…In eukaryotic cells, the degradation of the mRNA poly(A) tail (deadenylation) is a crucial step in the regulation of gene expression. The Ccr4-Not complex is…”
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