Search Results - "Balabanyan, V. Yu"

Efficacy of a new colloidal form of low-sialylated polylactide-based erythropoietin in experimental hemorrhagic stroke in rats by Elizarova, O. S., Balaban’yan, V. Yu, Shipulo, E. V., Maksimenko, O. O., Vanchugova, L. V., Litvinova, S. A., Garibova, T. L., Voronina, T. A., Gel’perina, S. É.

“…The aim of the present work was to develop methods for the preparation of a nanosomal form of low-sialylated recombinant human erythropoietin (ls-rhEPO), which…”
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Development of a method for quantitative determination of nitric oxide (NO) in rat tissues based on high-performance liquid chromatography and mass spectrometry by Popov, N. S., Gavrilenko, D. A., Baranov, M. S., Balabanyan, V. Yu

“…A quantitative assessment of nitric oxide (NO) production in body tissues is an urgent problem in pharmacology and biochemistry. The study of physiological…”
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Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential by Sagaradze, G.D., Basalova, N.A., Kirpatovsky, V.I., Ohobotov, D.A., Grigorieva, O.A., Balabanyan, V.Yu, Kamalov, A.A., Efimenko, A.Yu

“…[Display omitted] •Rat bilateral abdominal cryptorchidism model suits for evaluation of regenerative drug potency for testicular deficiency.•Contribution of…”
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Safety Study of an Original Mesenchymal Stromal Cell Secretome-Based Medicinal Product for Spermatogenesis Restoration by Monakova, A. O., Sagaradze, G. D., Balabanyan, V. Yu, Basalova, N. A., Matichina, A. A., Matichin, A. A., Kryshen, K. L., Popov, V. S., Akopyan, Zh. A., Efimenko, A. Yu

“…SCIENTIFIC RELEVANCE. Currently, there are no effective and safe medicinal products for idiopathic male infertility. Previous studies in two animal models of…”
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Experimental Study of the Efficacy and Safety of a New PEG-Based Laxative by Shekunova, E. V., Mazukina, E. V., Vavilova, V. A., Kashkin, V. V., Balabanyan, V. Yu, Fazylov, M. F., Makarova, M. N., Makarov, V. G.

“…Bowel-cleansing PEG-based agents, including Moviprep ® , are commonly used to prepare the large intestine for diagnostic examinations. PLNV-next is a newly…”
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Study of the specific toxic effects of the substance 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil, the original non-nucleoside inhibitor of human immunodeficiency virus type 1 (Retroviridae; Orthoretrovirinae; Lentivirus: Human immunodeficiency virus 1) reverse transcriptase by Gaidai, E. A., Kryshen, K. L., Jain (Korsakova), E. A., Demchenko, D. V., Kargopol’tseva, D. R., Katel’nikova, A. E., Gaidai, D. S., Balabanyan, V. Yu

“…Introduction. Combination antiretroviral therapy is currently the main component of treatment for human immunodeficiency virus (HIV) infected patients. At the…”
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Development and Biopharmaceutical Evaluation of Tablets Based on the Poorly Water-soluble Substance 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil by Demchenko, D. V., Jain (Korsakova), E. A., Balabanyan, V. Yu, Makarova, M. N., Makarov, V. G.

“…Introduction . 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil is a substance of scientific interest intended for the treatment of HIV-infection. However, its low…”
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EXPERIMENTAL STUDY OF TOXIC PROPERTIES OF VMU-2012-05 DRUG – ORIGINAL NON-NUCLEESIDE INHIBITOR OF HIV-1 REVERSE TRANSCRIPTASE by Vavilova, V. A., Shekunova, E. V., Jain (Korsakova), E. A., Balabanyan, V. Yu, Ozerov, A. A., Makarova, M. N., Makarov, V. G.

“…Antiretroviral therapy is currently the main component of treatment for HIV patients. The development of new, more effective and safer drugs is an urgent task…”
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Comparative Pharmacokinetics Study of 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil Substance and its Solid Dispersion Systems on Rabbits by Kosman, V. M., Demchenko, D. V., Jain (Korsakova), E. A., Makarov, V. G., Balabanyan, V. Yu

“…Introduction. The study of pharmacokinetics of medicinal substances and evaluation of their pharmacokinetic parameters is a necessary stage of pharmaceutical…”
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CHARACTERISATION AND STUDY OF 1- [2- (2-BENZOYLPHENOXY) ETHYL] -6-METHYLURACIL MECHANISM OF ACTION by Jain (Korsakova), E. A., Demchenko, D. V., Ozerov, A. A., Makarova, M. N., Makarov, V. G., Balabanyan, V. Yu

“…The aim of the study is to identify 1-[2-(2-benzoylphenoxy) ethyl]-6-methyluracil using various methods of analysis, as well as to study its action mechanism…”
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Optimization of Methods for Determination of the Encapsulation Efficiency of Doxorubicin in the Nanoparticles Based on Poly(lactic-co-glycolic acid) (PLGA) by Kovshova, T. S., Osipova, N. S., Fortuna, A. S., Ermolenko, Yu. V., Maksimenko, O. O., Balabanyan, V. Yu, Gelperina, S. E.

“…Introduction. Drug encapsulation efficiency (EE) is the important parameter of the nanoparticle-based drug formulations. Generally, the methods for evaluation…”
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Development of a New Amycolatopsis orientalis Strain for High-Yield Eremomycin Production by Dzhavakhiya, V. V., Glagoleva, E. V., Popova, E. D., Ovchinnikov, A. I., Skryabin, K. G., Shobolov, D. L., Balabanyan, V. Yu, Chernobrovkin, M. G.

“…A multistep random UV mutagenesis of an eremomycin-producing strain Amycolatopsis orientalis VKPM Ac-1125 with rather low productivity (0.5 g/L) and the…”
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Technologies and Perspectives of Liposomal Drug Application in Clinical Practice by Krasnopolskii, Yu. M., Grigor’eva, A. S., Katsai, A. G., Konakhovich, N. F., Prokhorov, V. V., Stadnichenko, A. V., Balaban’yan, V. Yu, Lyutik, A. I., Shvets, V. I.

“…In this article the results from studies of liposomes with the inclusion of active pharmacological substances (irinotecan, oxaliplatin, cytochrome C,…”
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SCIENTIFIC SCHOOL OF ACADEMICIAN VITALY I. SHVETS: BIONANOPHARMACEUTICAL TECHNOLOGIES OF INNOVATIVE DIRECTED-ACTION MEDICINAL PREPARATIONS AND MANPOWER TRAINING by V. I. Shvets, G. M. Sorokoumova, A. I. Lyutik, A. B. Pshenichnikova, D. I. Prokhorov, N. V. Rukosueva, A. G. Yakovenko, A. M. Khort, S. N. Chvalun, Yu. M. Krasnopolsky, V. Yu. Balabanyan, E. S. Severin, A. A. Kubatiev

“…The results of many years of scientific research in the field of physico-chemical biology and its most important direction - lipidology, conducted by the…”
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Involvement of BDNF and NGF in the Mechanism of Neuroprotective Effect of Human Recombinant Erythropoietin Nanoforms by Solev, I. N., Balabanyan, V. Yu, Volchek, I. A., Elizarova, O. S., Litvinova, S. A., Garibova, T. L., Voronina, T. A.

“…Human recombinant erythropoietin adsorbed on poly(butyl)cyanoacrylate nanoparticles and administered intraperitoneally in a dose of 0.05 mg/kg exhibited a…”
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Quantitative determination of cyclic guanosine monoposphate (c-GMP) in rat tissues using liquid chromatography and tandem mass spectrometry by Popov, N. S., Balabanyan, V. Yu, Kolgina, N. Yu, Petrov, G. A., Donskov, S. A., Atadzhanov, I. B.

“…Relevance. Cyclic 3′,5′-guanosine monophosphate is a secondary intracellular messenger that plays a key role in many physiological processes. Quantitative…”
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Development of approaches for studying the biodistribution of a bicistronic therapeutic plasmid construct in the mouse body by Dzhauari, S. S., Karagyaur, M. N., Balabanyan, V. Yu, Skryabina, M. N., Primak, A. L., Stambolsky, D. V.

“…Relevance . The use of gene therapy drugs for the treatment of genetic diseases and stimulation of regeneration processes is lengthy and involves repeated…”
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Quantitative determination of monoamine neurotransmitters in rat brain homogenates using HPLC-MS/MS by Popov, N. S., Gavrilenko, D. A., Balabanyan, V. Yu, Petrova, M. B., Donskov, S. A., Atadzhanov, I. B., Shatokhina, N. A.

“…Relevance. Evaluation of the effect of drugs on neurotransmitter processes is an important component of pharmacodynamic studies. The quantitative determination…”
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Cytotoxic Effect of Paclitaxel Incorporated in Nanoparticles Based on Lactic and Glycolic Acid Copolymer by Bojat, V., Baranov, D. S., Oganesyan, E. A., Hamdy, Y. M., Balaban’yan, V. Yu, Alyautdin, R. N.

“…Paclitaxel dosage form on nanoparticles of 200–300 nm based on lactic and glycolic acid copolymer was obtained by the co-precipitation method. The possibility…”
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Development of the Composition and Technology for Obtaining Paclitaxel Nanoscale Formulation Consisting of a Conjugate of Polymer Particles with a Protein Vector Molecule by Sokol, M. B., Yabbarov, N. G., Mollaeva, M. R., Chirkina (Fomicheva), M. V., Balaban'yan, V. Yu, Nikolskaya, E. D.

“…Introduction. The use of the anticancer drug paclitaxel is limited due to its high toxicity and lipophilicity. A new polymer composition of paclitaxel has been…”
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