Search Results - "Bal, Ramyasingh"
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Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion
Published in Cell reports (Cambridge) (28-11-2023)“…Type I interferon (IFN-I) response is the first line of host defense against invading viruses. In the absence of definite mouse models, the role of IFN-I in…”
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Journal Article -
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Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection
Published in The EMBO journal (01-12-2022)“…The NOD1/2‐RIPK2 is a key cytosolic signaling complex that activates NF‐κB pro‐inflammatory response against invading pathogens. However, uncontrolled NF‐κB…”
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Journal Article -
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Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses
Published in EMBO reports (04-11-2021)“…The type I interferon (IFN) response is the major host arsenal against invading viruses. IRGM is a negative regulator of IFN responses under basal conditions…”
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Journal Article