Search Results - "Bakulina, Olga"
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Multicomponent Reactions Involving Diazo Reagents: A 5-Year Update
Published in Molecules (Basel, Switzerland) (29-10-2021)“…This review summarizes recent developments in multicomponent reactions of diazo compounds. The role of diazo reagent and the type of interaction between…”
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2
Synthetic Routes to Approved Drugs Containing a Spirocycle
Published in Molecules (Basel, Switzerland) (20-05-2023)“…The use of spirocycles in drug discovery and medicinal chemistry has been booming in the last two decades. This has clearly translated into the landscape of…”
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3
Conjugates of Iron-Transporting N-Hydroxylactams with Ciprofloxacin
Published in Molecules (Basel, Switzerland) (18-06-2022)“…Screening of a library of novel N-hydroxylactams amenable by the Castagnoli-Cushman reaction identified four lead compounds that facilitated 55Fe transport…”
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4
Active Pharmaceutical Ingredient-Ionic Liquids (API-ILs): Nanostructure of the Glassy State Studied by Electron Paramagnetic Resonance Spectroscopy
Published in Molecules (Basel, Switzerland) (11-08-2022)“…Active Pharmaceutical Ingredient-Ionic Liquids (API-ILs) draw increasing interest as a particular class of ILs that possess unusual physicochemical properties…”
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5
Synthesis of spirocyclic tetrahydroisoquinolines (spiroTHIQs) via the Castagnoli-Cushman reaction
Published in Tetrahedron letters (15-10-2020)“…Three component Castagnoli-Cushman reaction of homophthalic anhydride, cyclic ketones and ammonium acetate followed by decarboxylation and lactam reduction…”
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6
Preparation and Synthetic Applications of Five-to-Seven-Membered Cyclic α-Diazo Monocarbonyl Compounds
Published in Molecules (Basel, Switzerland) (21-03-2022)“…The reactivity of cyclic α-diazo monocarbonyl compounds differs from that of their acyclic counterparts. In this review, we summarize the current literature…”
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Exploration of Spirocyclic Derivatives of Ciprofloxacin as Antibacterial Agents
Published in Molecules (Basel, Switzerland) (29-07-2022)“…The previously reported as well as newly synthesized derivatives of the 1-oxa-9-azaspiro[5.5]undecane were employed in the synthesis of thirty-six derivatives…”
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The Use of Aryl-Substituted Homophthalic Anhydrides in the Castagnoli-Cushman Reaction Provides Access to Novel Tetrahydroisoquinolone Carboxylic Acid Bearing an All-Carbon Quaternary Stereogenic Center
Published in Molecules (Basel, Switzerland) (02-12-2022)“…Novel aryl-substituted homophthalic acids were cyclodehydrated to the respective homophthalic anhydrides for use in the Castagnoli-Cushman reaction. With a…”
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9
One-Pot Sequence of Staudinger/aza-Wittig/Castagnoli-Cushman Reactions Provides Facile Access to Novel Natural-like Polycyclic Ring Systems
Published in Molecules (Basel, Switzerland) (22-11-2022)“…Realization of the one-pot Staudinger/aza-Wittig/Castagnoli-Cushman reaction sequence for a series of azido aldehydes and homophthalic anhydrides is described…”
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10
Extending the Scope of the New Variant of the Castagnoli–Cushman Cyclocondensation onto o-Methyl Benzoic Acids Bearing Various Electron-Withdrawing Groups in the α-Position
Published in Molecules (Basel, Switzerland) (25-10-2022)“…Based on the previously reported involvement of homophthalic acid monoesters in the Castagnoli–Cushman reaction-type cyclocondensation with imines, we tested a…”
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11
Validation of Structural Grounds for Anomalous Molecular Mobility in Ionic Liquid Glasses
Published in Molecules (Basel, Switzerland) (26-09-2021)“…Ionic liquid (IL) glasses have recently drawn much interest as unusual media with unique physicochemical properties. In particular, anomalous suppression of…”
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12
Dicarboxylic Acid Monoesters in β- and δ-Lactam Synthesis
Published in Molecules (Basel, Switzerland) (11-04-2022)“…A -(2-methoxy-2-oxoethyl)- -(phenylsulfonyl)glycine monomethyl ester of the respective dicarboxylic acid was involved in a reaction with imines promoted by…”
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13
Two Annulated Azaheterocyclic Cores Readily Available from a Single Tetrahydroisoquinolonic Castagnoli-Cushman Precursor
Published in Molecules (Basel, Switzerland) (28-04-2020)“…A novel approach to indolo[3,2- ]isoquinoline and dibenzo[ , ][1,6]naphthyridine tetracyclic systems was discovered based on switchable reduction of…”
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14
Facile Access to Fe(III)-Complexing Cyclic Hydroxamic Acids in a Three-Component Format
Published in Molecules (Basel, Switzerland) (28-02-2019)“…Cyclic hydroxamic acids can be viewed as effective binders of soluble iron and can therefore be useful moieties for employing in compounds to treat iron…”
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15
A speedy route to sterically encumbered, benzene-fused derivatives of privileged, naturally occurring hexahydropyrrolo[1,2- b ]isoquinoline
Published in Beilstein journal of organic chemistry (18-07-2017)“…A series of 15 benzene-fused hexahydropyrrolo[1,2- ]isoquinolonic acids with substantial degree of steric encumbrance has been prepared via a novel variant of…”
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16
Application of a TEMPO-Polypyrrole Polymer for NOx-Mediated Oxygen Electroreduction
Published in Catalysts (01-11-2022)“…The oxygen reduction reaction (ORR) is one of the key processes for electrochemical energy storage, such as the cathode process in fuel cells and metal–air…”
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17
Catalyst Loading Controls Chemoselectivity: Unusual Effect in Rhodium(II) Carbene Insertion Reactions with Tetrahydrofuran
Published in Catalysts (01-02-2023)“…(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones previously shown to yield two products in reactions with tetrahydrofuran mediated by rhodium…”
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18
Effects of Zwitterions on Structural Anomalies in Ionic Liquid Glasses Studied by EPR
Published in Nanomaterials (Basel, Switzerland) (26-07-2023)“…Ionic liquids (ILs) form a variety of nanostructures due to their amphiphilic nature. Recently, unusual structural phenomena have been found in glassy ILs near…”
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19
Design, synthesis, and biological evaluation of novel derivatives of dithiodiglycolic acid prepared via oxidative coupling of thiols
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)“…Human thioredoxin reductase 1 (TrxR1) is a selenocysteine-containing enzyme which plays a crucial role in regulating numerous redox signalling pathways within…”
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20
Inherent heterogeneities and nanostructural anomalies in organic glasses revealed by EPR
Published in Nanoscale advances (25-08-2021)“…Intriguing heterogeneities and nanostructural reorganizations of glassy ionic liquids (ILs) have recently been found using electron paramagnetic resonance…”
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