Search Results - "Baksh, Syeda"

Rig1 receptor plays a critical role in cardiac reprogramming via YY1 signaling by Baksh, Syeda S, Hu, Jiabiao, Pratt, Richard E, Dzau, Victor J, Hodgkinson, Conrad P

“…We discovered that innate immunity plays an important role in the reprogramming of fibroblasts into cardiomyocytes. In this report, we define the role of a…”
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Skeletal muscle differentiation induces wide-ranging nucleosome repositioning in muscle gene promoters by Harris, Sonalí, Anwar, Iqra, Baksh, Syeda S., Pratt, Richard E., Dzau, Victor J., Hodgkinson, Conrad P.

“…In a previous report, we demonstrated that Cbx1, PurB and Sp3 inhibited cardiac muscle differentiation by increasing nucleosome density around cardiac muscle…”
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Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4 by Suresh, Karthik, Servinsky, Laura, Reyes, Jose, Baksh, Syeda, Undem, Clark, Caterina, Michael, Pearse, David B, Shimoda, Larissa A

“…In acute respiratory distress syndrome, both reactive oxygen species (ROS) and increased intracellular calcium ([Ca(2+)]i) are thought to play important roles…”
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Modifying miRs for effective reprogramming of fibroblasts to cardiomyocytes by Wang, Xinghua, Baksh, Syeda S., Pratt, Richard E., Dzau, Victor J., Hodgkinson, Conrad P.

“…Reprogramming scar fibroblasts into cardiomyocytes has been proposed to reverse the damage associated with myocardial infarction. However, the limited…”
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Insights from molecular signature of in vivo cardiac c-Kit(+) cells following cardiac injury and β-catenin inhibition by Hodgkinson, Conrad P., Gomez, José A., Baksh, Syeda Samara, Payne, Alan, Schmeckpeper, Jeffrey, Pratt, Richard E., Dzau, Victor J.

“…There is much interest over resident c-Kit(+) cells in tissue regeneration. Their role in cardiac regeneration has been controversial. In this study we aim to…”
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Conservation of miR combo based direct cardiac reprogramming by Baksh, Syeda Samara, Hodgkinson, Conrad P.

“…There is considerable interest in regenerating the injured heart by reprogramming resident fibroblasts into new functional cardiomyocytes. Cardiac…”
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Abstract 9742: Conservation of Mir Direct Cardiac Reprogramming Across Several Mammalian Species by Baksh, Syeda, Pratt, Richard E, Dzau, Victor J, Hodgkinson, Conrad

“…There is considerable interest in regenerating the injured heart by reprogramming resident fibroblasts into new functional cardiomyocytes. Cardiac…”
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Abstract 12033: The IFNb-Gbp7 Pathway Plays an Important Role in Activating Cardiomyocyte Genes by Wang, Xinghua, Baksh, Syeda, Pratt, Richard E, dzau, victor, Hodgkinson, Conrad

“…We discovered that reprogramming scar fibroblasts into cardiomyocytes requires activation of innate immunity. Recently, we found that innate immunity exerts…”
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Abstract 9746: Rig-1 Agonists Regulate Cardiac Reprogramming via Yy1 by Baksh, Syeda, Hu, Jiabiao, Pratt, Richard E, Dzau, Victor J, Hodgkinson, Conrad

“…We have discovered that innate immunity plays an important role in the reprogramming of fibroblasts into cardiomyocytes. Previously, we have focused on the…”
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Abstract 15541: Novel Molecular Entity for Effective Cardiac Regeneration: 5’ppp Microrna Induces Reprogramming and Accelerates Cardiomyocyte Maturation by Hu, Jiabiao, Hodgkinson, Conrad, Baksh, Syeda S, Pratt, Richard E, Dzau, Victor J

“…We have shown that miR combo directly reprograms fibroblasts into cardiomyocytes. However, both in vitro and in vivo, the generated cardiomyocytes are…”
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A novel Cbx1, PurB, and Sp3 complex mediates long-term silencing of tissue- and lineage-specific genes by Baksh, Syeda Samara, Pratt, Richard E., Gomez, José, Dzau, Victor J., Hodgkinson, Conrad P.

“…miRNA-based cellular fate reprogramming offers an opportunity to investigate the mechanisms of long-term gene silencing. To further understand how genes are…”
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The aquaporin 1 C-terminal tail is required for migration and growth of pulmonary arterial myocytes by Lai, Ning, Lade, Julie, Leggett, Kyle, Yun, Xin, Baksh, Syeda, Chau, Eric, Crow, Michael T, Sidhaye, Venkataramana, Wang, Jian, Shimoda, Larissa A

“…Pulmonary arterial smooth muscle cell (PASMC) proliferation and migration are important contributors to the vascular remodeling that occurs during development…”
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Rho kinase and Na+/H+ exchanger mediate endothelin‐1‐induced pulmonary arterial smooth muscle cell proliferation and migration by Huetsch, John C., Walker, Jasmine, Undem, Clark, Lade, Julie, Yun, Xin, Baksh, Syeda, Jiang, Haiyang, Lai, Ning, Shimoda, Larissa A.

“…Excessive production of endothelin‐1 (ET‐1) has been observed in almost all forms of pulmonary hypertension. ET‐1, a highly potent vasoconstrictor, can also…”
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