Search Results - "Bakker, Hester"

Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded AbEsel liposomes by Asgeirsdóttir, Sigrídur A, Zwiers, Peter J, Morselt, Henriëtte W, Moorlag, Hendrik E, Bakker, Hester I, Heeringa, Peter, Kok, Jan Willem, Kallenberg, Cees G M, Molema, Grietje, Kamps, Jan A A M

“…E-selectin-directed targeted drug delivery was analyzed in anti-glomerular basement membrane glomerulonephritis. Liposomes conjugated with anti-E-selectin…”
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Site-specific inhibition of glomerulonephritis progression by targeted delivery of dexamethasone to glomerular endothelium by Asgeirsdóttir, Sigridur A, Kamps, Jan A A M, Bakker, Hester I, Zwiers, Peter J, Heeringa, Peter, van der Weide, Karen, van Goor, Harry, Petersen, Arjen H, Morselt, Henriëtte, Moorlag, Henk E, Steenbergen, E, Kallenberg, Cees G, Molema, Grietje

“…Glomerulonephritis represents a group of renal diseases with glomerular inflammation as a common pathologic finding. Because of the underlying immunologic…”
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The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo by Greupink, Rick, Bakker, Hester I, Bouma, Wilma, Reker-Smit, Catharina, Meijer, Dirk K F, Beljaars, Leonie, Poelstra, Klaas

“…Hepatic stellate cell (HSC) proliferation is a key event in liver fibrosis; therefore, pharmacological intervention with antiproliferative drugs may result in…”
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Mannose-6-phosphate/insulin-like growth factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells by GREUPINK, Rick, BAKKER, Hester I, VAN GOOR, Harry, DE BORST, Martin H, BELJAARS, Leonie, POELSTRA, Klaas

“…The insulin-like growth factor axis plays an important role in fibrogenesis. However, little is known about mannose-6-phosphate/Insulin-like growth factor-II…”
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Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell by Greupink, Rick, Bakker, Hester I., Reker-Smit, Catharina, van Loenen-Weemaes, Anne-miek, Kok, Robbert-Jan, Meijer, Dirk K.F., Beljaars, Leonie, Poelstra, Klaas

“…Hepatic stellate cell (HSC) activation and proliferation are key events in the pathology of liver fibrosis. Inhibiting these parameters, therefore, is a…”
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Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo by Beljaars, Leonie, van der Strate, Barry W.A., Bakker, Hester I., Reker-Smit, Catharina, van Loenen-Weemaes, Anne-miek, Wiegmans, Frouwke C., Harmsen, Martin C., Molema, Grietje, Meijer, Dirk K.F.

“…Lactoferrin is an antimicrobial agent, that, amongst other viruses, inhibits cytomegalovirus (CMV). In this study, we addressed the mechanism(s) by which…”
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A phase I/IIa study with succinylated human serum albumin (Suc-HSA), a candidate HIV-1 fusion inhibitor by VERMEULEN, Joost N, MEIJER, Dirk K. F, OVER, Jan, LANGE, Joep M. A, PROOST, Johannes H, BAKKER, Hester I, BELJAARS, Leonie, WIT, Ferdinand W. N. M, PRINS, Jan M

“…Succinylated human serum albumin (Suc-HAS) is a negatively charged neo-glycoprotein that binds to the positively charged V3-loop of HIV-1 gp120, acting as…”
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Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro by van der Strate, Barry W.A., De Boer, Froukje M., Bakker, Hester I., Meijer, Dirk K.F., Molema, Grietje, Harmsen, Martin C.

“…Human cytomegalovirus (HCMV) causes severe morbidity and mortality in immunocompromised patients. Treatment of HCMV infections with conventional antiviral…”
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Design and Fungicidal Activity of Mucoadhesive Lactoferrin Tablets for the Treatment of Oropharyngeal Candidosis by Kuipers, Mirjam E., Heegsma, Jannet, Bakker, Hester I., Meijer, Dick K. F., Swart, Pieter J., Frijlink, Erik W., Eissens, Anco C., Vries-Hospers, Hilly G. de, J. M. van den Berg, Jeroen

“…Lactoferrin (Lf) is a potential drug candidate for the treatment of oropharyngeal Candida infections. However, for an effective therapeutic treatment an…”
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354 Hepatic stellate cell specific delivery of mycophenolic acid as a strategy to treat liver fibrosis by Greupink, Rick, Bakker, Hester, van Loenen-Weemaes, Anne-Miek, Reker-Smit, Catharina, Meijer, Dirk, Beljaars, Leonie, Poelstra, Klaas

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The antiviral protein human lactoferrin is distributed in the body to cytomegalovirus (CMV) infection-prone cells and tissues by BELJAARS, Leonie, BAKKER, Hester I, VAN DER STRATE, Barry W. A, SMIT, Catharina, DUIJVESTIJN, Adrian M, MEIJER, Dirk K. F, MOLEMA, Grietje

“…Lactoferrin has anti-Cytomegalovirus (CMV) and -HIV properties in vitro. However, the pharmacokinetic behavior of the 80-kD protein has not been well defined…”
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