Search Results - "Bakker, E.M."

Determining presence of lung disease in young children with cystic fibrosis: Lung clearance index, oxygen saturation and cough frequency by Bakker, E.M, van der Meijden, J.C, Nieuwhof, E.M, Hop, W.C.J, Tiddens, H.A.W.M

“…Abstract Background Accurate assessment of pulmonary status in young children with cystic fibrosis (CF) requires sensitive and objective monitoring techniques…”
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Conserved NPPB+ Border Zone Switches From MEF2- to AP-1–Driven Gene Program by van Duijvenboden, Karel, de Bakker, Dennis E.M, Man, Joyce C.K, Janssen, Rob, Günthel, Marie, Hill, Matthew C, Hooijkaas, Ingeborg B, van der Made, Ingeborg, van der Kraak, Petra H, Vink, Aryan, Creemers, Esther E, Martin, James F, Barnett, Phil, Bakkers, Jeroen, Christoffels, Vincent M

“…BACKGROUND:Surviving cells in the postinfarction border zone are subjected to intense fluctuations of their microenvironment. Recently, border zone…”
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74 Adherence to rhDNase inhaled via an AKITA2® APIXNEB device during a clinical trial by Kroneberg, P, Bakker, E.M, Schulze, A, Steinkamp, G, Tiddens, H.A.W.M, Scheuch, G

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Monitoring of young children with CF by Bakker, E.M, van der Meijden, C, Nieuwhof, E.M, Tiddens, H.A.W.M

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Loss of the Polycomb group protein Rnf2 results in derepression of tbx-transcription factors and defects in embryonic and cardiac development by Chrispijn, Naomi D., Elurbe, Dei M., Mickoleit, Michaela, Aben, Marco, de Bakker, Dennis E.M., Andralojc, Karolina M., Huisken, Jan, Bakkers, Jeroen, Kamminga, Leonie M.

“…The Polycomb group (PcG) protein family is a well-known group of epigenetic modifiers. We used zebrafish to investigate the role of Rnf2, the enzymatic subunit…”
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Efficacy of peripheral deposition of inhaled rhDNase in CF patients during a respiratory tract exacerbation by Bakker, E.M, Volpi, S, Salonini, E, Müllinger, B, Kroneberg, P, Hop, W.C.J, Assael, B.M, Tiddens, H.A.W.M

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Ultrasonographic evaluation of equine tendons: a quantitative in vitro study of the effects of amplifier gain level, transducer-tilt, and transducer-displacement by Schie, J.T.M. van, Bakker, E.M, Weeren, P.R. van

“…The objective of the in vitro experiments described in this paper was to quantify the effects of some instrumental variables on the quantitative evaluation, by…”
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Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation by BAKKER, E. M, VOLPI, S, SALONINI, E, VAN DER WIEL-KOOIJ, E. C, SINTNICOLAAS, C. J. J. C. M, HOP, W. C. J, ASSAEL, B. M, MERKUS, P. J. F. M, TIDDENS, H. A. W. M

“…Better treatment of obstructed small airways is needed in cystic fibrosis. This study investigated whether efficient deposition of dornase alfa in the small…”
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Small airway deposition of dornase alfa during exacerbations in cystic fibrosis; a randomized controlled clinical trial: Dornase Alfa for the Small Airways in CF: DEPTH by Bakker, E.M., Volpi, S., Salonini, E., Müllinger, B., Kroneberg, P., Bakker, M., Hop, W.C.J., Assael, B.M., Tiddens, H.A.W.M.

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Small airway deposition of dornase alfa during exacerbations in cystic fibrosis; a randomized controlled clinical trial by Bakker, E.M., Volpi, S., Salonini, E., Müllinger, B., Kroneberg, P., Bakker, M., Hop, W.C.J., Assael, B.M., Tiddens, H.A.W.M.

“…Introduction Small airway obstruction is important in the pathophysiology of cystic fibrosis (CF) lung disease. Additionally, many CF patients lose lung…”
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Turquoise killifish: A natural model of age-dependent brain degeneration by de Bakker, Dennis E.M., Valenzano, Dario R.

“…Turquoise killifish (Nothobranchius furzeri) are naturally short-lived vertebrates that display a wide range of spontaneous age-related changes, including…”
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Cardiac regenerative capacity: an evolutionary afterthought? by Nguyen, Phong D., de Bakker, Dennis E. M., Bakkers, Jeroen

“…Cardiac regeneration is the outcome of the highly regulated interplay of multiple processes, including the inflammatory response, cardiomyocyte…”
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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart by Honkoop, Hessel, de Bakker, Dennis Em, Aharonov, Alla, Kruse, Fabian, Shakked, Avraham, Nguyen, Phong D, de Heus, Cecilia, Garric, Laurence, Muraro, Mauro J, Shoffner, Adam, Tessadori, Federico, Peterson, Joshua Craiger, Noort, Wendy, Bertozzi, Alberto, Weidinger, Gilbert, Posthuma, George, Grün, Dominic, van der Laarse, Willem J, Klumperman, Judith, Jaspers, Richard T, Poss, Kenneth D, van Oudenaarden, Alexander, Tzahor, Eldad, Bakkers, Jeroen

“…While the heart regenerates poorly in mammals, efficient heart regeneration occurs in zebrafish. Studies in zebrafish have resulted in a model in which…”
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74 Adherence to rhDNase inhaled via an AKITA 2® APIXNEB device during a clinical trial by Kroneberg, P., Bakker, E.M., Schulze, A., Steinkamp, G., Tiddens, H.A.W.M., Scheuch, G.

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Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regeneration by de Bakker, Dennis E M, Bouwman, Mara, Dronkers, Esther, Simões, Filipa C, Riley, Paul R, Goumans, Marie-José, Smits, Anke M, Bakkers, Jeroen

“…Fibroblasts are activated to repair the heart following injury. Fibroblast activation in the mammalian heart leads to a permanent fibrotic scar that impairs…”
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Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration by Nguyen, Phong D, Gooijers, Iris, Campostrini, Giulia, Verkerk, Arie O, Honkoop, Hessel, Bouwman, Mara, de Bakker, Dennis E M, Koopmans, Tim, Vink, Aryan, Lamers, Gerda E M, Shakked, Avraham, Mars, Jonas, Mulder, Aat A, Chocron, Sonja, Bartscherer, Kerstin, Tzahor, Eldad, Mummery, Christine L, de Boer, Teun P, Bellin, Milena, Bakkers, Jeroen

“…Zebrafish hearts can regenerate by replacing damaged tissue with new cardiomyocytes. Although the steps leading up to the proliferation of surviving…”
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Zebrafish prrx1a mutants have normal hearts by Tessadori, Federico, de Bakker, Dennis E. M., Barske, Lindsey, Nelson, Nellie, Algra, Hermine A., Willekers, Sven, Nichols, James T., Crump, J. Gage, Bakkers, Jeroen

“…A number of explanations have been proposed for discrepancies between morpholino knockdown phenotypes and the lack thereof in germline mutants: off-target…”
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Computerized ultrasonographic tissue characterization of equine superficial digital flexor tendons by means of stability quantification of echo patterns in contiguous transverse ultrasonographic images by Schie, H.T.M. van, Bakker, E.M, Jonker, A.J, Weeren, P.R. van

“…To describe a method of computerized ultrasonographic tissue characterization that includes structures below the size limits of resolution in equine…”
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Epigenetic State Changes Underlie Metabolic Switch in Mouse Post-Infarction Border Zone Cardiomyocytes by Günthel, Marie, van Duijvenboden, Karel, de Bakker, Dennis E M, Hooijkaas, Ingeborg B, Bakkers, Jeroen, Barnett, Phil, Christoffels, Vincent M

“…Myocardial infarction causes ventricular muscle loss and formation of scar tissue. The surviving myocardium in the border zone, located adjacent to the…”
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Ultrasonographic tissue characterization of equine superficial digital flexor tendons by means of gray level statistics by Schie, H.T.M. van, Bakker, E.M, Jonker, A.M, Weeren, P.R. van

“…To correlate quantitative analysis of ultrasonographic images of normal (injury-free) equine superficial digital flexor (SDF) tendons and equine SFD tendons…”
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