Search Results - "Bakker, Clare"
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Calcineurin homologous protein isoform 2 supports tumor survival via the sodium hydrogen exchanger isoform 1 in non-small cell lung cancer
Published in Tumor biology (01-07-2020)“…Maintaining intracellular pH is crucial for preserving healthy cellular behavior and, when dysregulated, results in increased proliferation, migration, and…”
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Expression and Regulation of CHP and NHE in Cancer
Published in The FASEB journal (01-04-2018)“…The hypoxic and serum starved environment of metastasizing cancer cells requires a mechanism to overcome the low intracellular pH induced by the Warburg…”
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Palmitoylation and Phosphorylation–Impact on NHE1 Transport
Published in The FASEB journal (01-04-2019)“…The sodium hydrogen exchanged isoform 1 (NHE1) has two key roles. First is to regulate intracellular pH (pHi) by exchanging an intracellular proton for an…”
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Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
Published in Molecular psychiatry (30-09-2024)“…MEF2C is a critical transcription factor in neurodevelopment, whose loss-of-function mutation in humans results in MEF2C haploinsufficiency syndrome (MHS), a…”
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Sodium hydrogen exchanger (NHE1) palmitoylation and potential functional regulation
Published in Life sciences (1973) (01-01-2022)“…Determine the effect of palmitoylation on the sodium hydrogen exchanger isoform 1 (NHE1), a member of the SLC9 family. NHE1 expressed in native rat tissues or…”
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The Affective Gallery: A Naturalistic Exploration of the Relationship Between Attentional Bias and Depressive Symptoms
Published in Revista internacional de psicología y terapia psicológica (01-06-2019)“…[...]bipolar patients studied across all phases of their disorder (euthymic, manic, depressed) uniquely demonstrated an expected EM bias (a decrease in…”
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