Search Results - "Bakker, Cathy E."

Altered Differentiation of Neural Stem Cells in Fragile X Syndrome by Maija Castrén, Topi Tervonen, Virve Kärkkäinen, Seppo Heinonen, Castrén, Eero, Kim Larsson, Cathy E. Bakker, Oostra, Ben A., Karl Åkerman

“…Fragile X syndrome, a common form of inherited mental retardation, is caused by the absence of the fragile X mental retardation protein (FMRP) due to a…”
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Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice by Van Dam, Debby, D'Hooge, Rudi, Hauben, Ehud, Reyniers, Edwin, Gantois, Ilse, Bakker, Cathy E, Oostra, Ben A, Kooy, R.Frank, De Deyn, Peter P

“…Fmr1 knockout mice are an animal model for fragile X syndrome, the most common form of heritable mental retardation in humans. Fmr1 knockout mice exhibit…”
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BDNF Regulates the Expression of Fragile X Mental Retardation Protein mRNA in the Hippocampus by Castrén, Maija, Lampinen, Katariina E, Miettinen, Riitta, Koponen, Eija, Sipola, Ilkka, Bakker, Cathy E, Oostra, Ben A, Castrén, Eero

“…Both fragile X mental retardation protein (FMRP) and brain-derived neurotrophic factor (BDNF) are implicated in the maturation of neurons and in the higher…”
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Macroorchidism in FMR1 Knockout Mice Is Caused by Increased Sertoli Cell Proliferation during Testicular Development by Slegtenhorst-Eegdeman, Karin E., de Rooij, Dirk G., Verhoef-Post, Miriam, van de Kant, Henk J. G., Bakker, Cathy E., Oostra, Ben A., Grootegoed, J. Anton, Themmen, Axel P. N.

“…Abstract The fragile X syndrome is the most frequent hereditary form of mental retardation. This X-linked disorder is, in most cases, caused by an unstable and…”
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Neuroanatomy of the fragile X knockout mouse brain studied using in vivo high resolution magnetic resonance imaging by Kooy, R F, Reyniers, E, Verhoye, M, Sijbers, J, Bakker, C E, Oostra, B A, Willems, P J, Van Der Linden, A

“…Magnetic resonance imaging (MRI) of the brain of fragile X patients, the most frequent form of inherited mental retardation, has revealed abnormalities in the…”
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Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes by Musumeci, Sebastiano A., Calabrese, Giuseppe, Bonaccorso, Carmela M., D'Antoni, Simona, Brouwer, Judith R., Bakker, Cathy E., Elia, Maurizio, Ferri, Raffaele, Nelson, David L., Oostra, Ben A., Catania, Maria Vincenza

“…The Fmr1 knockout (KO) mouse is characterized by an increased audiogenic seizure (AGS) susceptibility and is considered a good animal model for epilepsy and…”
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Synergistic Effect of Histone Hyperacetylation and DNA Demethylation in the Reactivation of the FMR1 Gene by Chiurazzi, Pietro, Grazia Pomponi, M., Pietrobono, Roberta, Bakker, Cathy E., Neri, Giovanni, Oostra, Ben A.

“…Most fragile X syndrome patients have expansion of a (CGG)n sequence with >200 repeats (full mutation) in the FMR1 gene responsible for this condition…”
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Immunocytochemical and Biochemical Characterization of FMRP, FXR1P, and FXR2P in the Mouse by Bakker, Cathy E., de Diego Otero, Yolanda, Bontekoe, Carola, Raghoe, Prawien, Luteijn, Tanya, Hoogeveen, André T., Oostra, Ben A., Willemsen, Rob

“…Fragile X syndrome is caused by the absence of expression of the FMR1 gene. Both FXR1 and FXR2 are autosomal gene homologues of FMR1. The products of the three…”
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Characterization and localization of the FMR-1 gene product associated with fragile X syndrome by Verheij, Coleta, Bakker, Cathy E, de Graaff, Esther, Keulemans, Joke, Willemsen, Rob, Verkerk, Annemieke J. M. H, Galjaard, Hans, Reuser, Arnold J. J, Hoogeveen, André T, Oostra, Ben A

“…The fragile X syndrome is the most frequent form of inherited mental retardation after Down's syndrome, having an incidence of one in 1,250 males. The fragile…”
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Different Targets for the Fragile X-Related Proteins Revealed by Their Distinct Nuclear Localizations by Tamanini, Filippo, Bontekoe, Carola, Bakker, Cathy E., van Unen, Leontine, Anar, Burcu, Willemsen, Rob, Yoshida, Minoru, Galjaard, Hans, Oostra, Ben A., Hoogeveen, André T.

“…Fragile X syndrome is caused by the absence of the fragile X mental retardation protein (FMRP). FMRP and its structural homologues FXR1P and FXR2P form a…”
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Knockout mouse model for Fxr2: a model for mental retardation by BONTEKOE, Carola J. M, MCILWAIN, Kellie L, NGAN CHING CHENG, MERRIWEATHER, Michelle, HOOGEVEEN, Andre T, NELSON, David, PAYLOR, Richard, OOSTRA, Ben A, NIEUWENHUIZEN, Ingeborg M, YUVA-PAYLOR, Lisa A, NELLIS, Anna, WILLEMSEN, Rob, ZHE FANG, KIRKPATRICK, Laura, BAKKER, Cathy E, MCANINCH, Robin

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No evidence for disruption of normal patterns of mRNA localization in dendrites or dendritic transport of recently synthesized mRNA in FMR1 knockout mice, a model for human fragile-X mental retardation syndrome by Steward, Oswald, Bakker, Cathy E, Willems, Patrick J, Oostra, Ben A

“…RECENT studies have revealed that FMRP, the gene product of the fragile-X gene FMR1, is an RNA-binding protein. These and other data have led to the idea that…”
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Knockout mouse model for Fxr2: a model for mental retardation by Bontekoe, Carola J M, McIlwain, Kellie L, Nieuwenhuizen, Ingeborg M, Yuva-Paylor, Lisa A, Nellis, Anna, Willemsen, Rob, Fang, Zhe, Kirkpatrick, Laura, Bakker, Cathy E, McAninch, Robin, Cheng, Ngan Ching, Merriweather, Michelle, Hoogeveen, Andre T, Nelson, David, Paylor, Richard, Oostra, Ben A

“…Fragile X syndrome is a common form of mental retardation caused by the absence of the FMR1 protein, FMRP. Fmr1 knockout mice exhibit a phenotype with some…”
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Long-term potentiation in the hippocampus of fragile X knockout mice by Godfraind, Jean-Marie, Reyniers, Edwin, De Boulle, Kristel, D'Hooge, Rudi, De Deyn, Peter P., Bakker, Cathy E., Oostra, Ben A., Kooy, R. Frank, Willems, Patrick J.

“…To gain more insight in the physiological function of the fragile X gene (FMR1) and the mechanisms leading to fragile X syndrome, the Fmr1 gene has been…”
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Generalized glycogen storage and cardiomegaly in a knockout mouse model of Pompe disease by BIJVOET, A. G. A, VAN DE KAMP, E. H. M, VAN DER PLOEG, A. T, KROOS, M. A, DING, J.-H, YANG, B. Z, VISSER, P, BAKKER, C. E, VERBEET, M. P, OOSTRA, B. A, REUSER, A. J. J

“…Glycogen storage disease type II (GSDII; Pompe disease), caused by inherited deficiency of acid alpha-glucosidase, is a lysosomal disorder affecting heart and…”
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Corrigendum to “Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice” : [Behav. Brain Res. 117 (2000) 127–136] by Van Dam, Debby, D'Hooge, Rudi, Hauben, Ehud, Reyniers, Edwin, Gantois, Ilse, Bakker, Cathy E, Oostra, Ben A, Kooy, R Frank, De Deyn, Peter P

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Characterization of FMR1 proteins isolated from different tissues by Verheij, C, de Graaff, E, Bakker, C E, Willemsen, R, Willems, P J, Meijer, N, Galjaard, H, Reuser, A J, Oostra, B A, Hoogeveen, A T

“…FMR1 protein expression was studied in different tissues. In human, monkey and murine tissues, high molecular mass FMR1 proteins (67-80 kDa) are found, as…”
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Macroorchidism in FMR1 Knockout Mice Is Caused by Increased Sertoli Cell Proliferation during Testicular Development1 by Slegtenhorst-Eegdeman, Karin E, de Rooij, Dirk G, Verhoef-Post, Miriam, van de Kant, Henk J. G, Bakker, Cathy E, Oostra, Ben A, Grootegoed, J. Anton, Themmen, Axel P. N

“…The fragile X syndrome is the most frequent hereditary form of mental retardation. This X-linked disorder is, in most cases, caused by an unstable and…”
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Mean corpuscular hemoglobin is not increased in Fmr1 knockout mice by REYNIERS, E, VAN BOCKSTAELE, D. R, DE BOULLE, K, KOOY, R. F, BAKKER, C. E, OOSTRA, B. A, WILLEMS, P. J

“…A slight increase in mean corpuscular hemoglobin (MCH) has been reported in erythrocytes from human fragile X patients. As it is difficult to perform…”
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Transgenic mouse model for the fragile X syndrome by Kooy, R. Frank, D'Hooge, Rudi, Reyniers, Edwin, Bakker, Cathy E., Nagels, Guy, De Boulle, Kristel, Storm, Katrien, Clincke, Gilbert, De Deyn, Peter P., Oostra, Ben A., Willems, Patrick J.

“…Transgenic fragile X knockout mice have been constructed to provide an animal model to study the physiologic function of the fragile X gene (FMR1) and to gain…”
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