Search Results - "Bakker, Alexander B. H"

Validation of the Rapid Fluorescent Focus Inhibition Test for Rabies Virus-Neutralizing Antibodies in Clinical Samples by KOSTENSE, Stefan, MOORE, Susan, COMPANJEN, Arjen, BAKER, Alexander B. H, MARISSEN, Wilfred E, EYBEN, Rie Von, WEVERLING, Gerrit Jan, HANLON, Cathleen, GOUDSMIT, Jaap

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An Activating Immunoreceptor Complex Formed by NKG2D and DAP10 by Wu, Jun, Song, Yaoli, Alexander B. H. Bakker, Bauer, Stefan, Spies, Thomas, Lanier, Lewis L., Phillips, Joseph H.

“…Many immune receptors are composed of separate ligand-binding and signal-transducing subunits. In natural killer (NK) and T cells, DAP10 was identified as a…”
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Novel Human Monoclonal Antibody Combination Effectively Neutralizing Natural Rabies Virus Variants and Individual In Vitro Escape Mutants by BAKKER, Alexander B. H, MARISSEN, Wilfred E, DIETZSCHOLD, Bernhard, RUPPRECHT, Charles E, GOUDSMIT, Jaap, KRAMER, R. Arjen, RICE, Amy B, WELDON, William C, NIEZGODA, Michael, HANLON, Cathleen A, THIJSSE, Sandra, BACKUS, Harold H. J, DE KRUIF, John

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Qualitative and Semiquantitative Analysis of Composite Mixtures of Antibodies by Native Mass Spectrometry by Rosati, Sara, Thompson, Natalie J, Barendregt, Arjan, Hendriks, Linda J. A, Bakker, Alexander B. H, de Kruif, John, Throsby, Mark, van Duijn, Esther, Heck, Albert J. R

“…Native mass spectrometry was evaluated for the qualitative and semiquantitative analysis of composite mixtures of antibodies representing biopharmaceutical…”
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Comparison of an Anti-Rabies Human Monoclonal Antibody Combination with Human Polyclonal Anti-Rabies Immune Globulin by Goudsmit, Jaap, Marissen, Wilfred E., Weldon, William C., Niezgoda, Michael, Hanlon, Cathleen A., Rice, Amy B., Kruif, John de, Dietzschold, Bernhard, Bakker, Alexander B. H., Rupprecht, Charles E.

“…The World Health Organization estimates human mortality from endemic canine rabies to be 55,000 deaths/year. Limited supply hampers the accessibility of…”
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Molecular and Biological Characterization of Human Monoclonal Antibodies Binding to the Spike and Nucleocapsid Proteins of Severe Acute Respiratory Syndrome Coronavirus by VAN DEN BRINK, Edward N, TER MEULEN, Jan, MARTINA, Byron E, OSTERHAUS, Albert D. M. E, PREISER, Wolfgang, DOERR, Hans Wilhelm, DE KRUIF, John, GOUDSMIT, Jaap, COX, Freek, JONGENEELEN, Mandy A. C, THIJSSE, Alexandra, THROSBY, Mark, MARISSEN, Wilfred E, ROOD, Pauline M. L, BAKKER, Alexander B. H, GELDERBLOM, Hans R

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Novel Rabies Virus-Neutralizing Epitope Recognized by Human Monoclonal Antibody: Fine Mapping and Escape Mutant Analysis by MARISSEN, Wilfred E, ARJEN KRAMER, R, JONGENEELEN, Mandy, THIJSSE, Sandra, THROSBY, Mark, DE KRUIF, John, RUPPRECHT, Charles E, DIETZSCHOLD, Bernhard, GOUDSMIT, Jaap, BAKKER, Alexander B. H, RICE, Amy, WELDON, William C, NIEZGODA, Michael, FABER, Milosz, SLOOTSTRA, Jerry W, MELOEN, Rob H, CLIJSTERS-VAN DER HORST, Marieke, VISSER, Therese J

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Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose by de Vries Schultink, Aurelia H. M., Doornbos, Robert P., Bakker, Alexander B. H., Bol, Kees, Throsby, Mark, Geuijen, Cecile, Maussang, David, Schellens, Jan H. M., Beijnen, Jos H., Huitema, Alwin D. R.

“…Summary Introduction MCLA-128 is a bispecific monoclonal antibody targeting the HER2 and HER3 receptors. Pharmacokinetics (PK) and pharmacodynamics (PD) of…”
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C-type lectin-like molecule-1: A novel myeloid cell surface marker associated with acute myeloid leukemia by BAKKER, Alexander B. H, VAN DEN OUDENRIJN, Sonja, MARISSEN, Wilfred E, RADOSEVIC, Katarina, THROSBY, Mark, SCHUURHUIS, Gerrit Jan, OSSENKOPPELE, Gert J, DE KRUIF, John, GOUDSMIT, Jaap, KRUISBEEK, Ada M, BAKKER, Arjen Q, FELLER, Nicole, VAN MEIJER, Marja, BIA, Judith A, JONGENEELEN, Mandy A. C, VISSER, Therese J, BIJL, Nora, GEUIJEN, Cecilia A. W

“…Acute myeloid leukemia (AML) has a poor prognosis due to treatment-resistant relapses. A humanized anti-CD33 antibody (Mylotarg) showed a limited response rate…”
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A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1 by De Nardis, Camilla, Hendriks, Linda J.A., Poirier, Emilie, Arvinte, Tudor, Gros, Piet, Bakker, Alexander B.H., de Kruif, John

“…Bispecific antibodies combine two different antigen-binding sites in a single molecule, enabling more specific targeting, novel mechanisms of action, and…”
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Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets by ter Meulen, Jan, Bakker, Alexander BH, van den Brink, Edward N, Weverling, Gerrit J, Martina, Byron EE, Haagmans, Bart L, Kuiken, Thijs, de Kruif, John, Preiser, Wolfgang, Spaan, Willy, Gelderblom, Hans R, Goudsmit, Jaap, Osterhaus, Albert DME

“…SARS coronavirus continues to cause sporadic cases of severe acute respiratory syndrome (SARS) in China. No active or passive immunoprophylaxis for disease…”
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A human monoclonal antibody cocktail as a novel component of rabies postexposure prophylaxis by de Kruif, John, Bakker, Alexander B H, Marissen, Wilfred E, Kramer, R Arjen, Throsby, Mark, Rupprecht, Charles E, Goudsmit, Jaap

“…The currently recommended treatment for individuals exposed to rabies virus is the combined administration of rabies vaccine and rabies immune globulin (RIG)…”
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Myeloid DAP12-Associating Lectin (MDL)-1 Is a Cell Surface Receptor Involved in the Activation of Myeloid Cells by Alexander B. H. Bakker, Baker, Elizabeth, Sutherland, Grant R., Phillips, Joseph H., Lanier, Lewis L.

“…Crosslinking of immunoreceptor tyrosine-based activation motif (ITAM)-containing receptor complexes on a variety of cells leads to their activation through the…”
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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade by Geuijen, Cecile, Tacken, Paul, Wang, Liang-Chuan, Klooster, Rinse, van Loo, Pieter Fokko, Zhou, Jing, Mondal, Arpita, Liu, Yao-bin, Kramer, Arjen, Condamine, Thomas, Volgina, Alla, Hendriks, Linda J. A., van der Maaden, Hans, Rovers, Eric, Engels, Steef, Fransen, Floris, den Blanken-Smit, Renate, Zondag-van der Zande, Vanessa, Basmeleh, Abdul, Bartelink, Willem, Kulkarni, Ashwini, Marissen, Wilfred, Huang, Cheng-Yen, Hall, Leslie, Harvey, Shane, Kim, Soyeon, Martinez, Marina, O’Brien, Shaun, Moon, Edmund, Albelda, Steven, Kanellopoulou, Chrysi, Stewart, Shaun, Nastri, Horacio, Bakker, Alexander B. H., Scherle, Peggy, Logtenberg, Ton, Hollis, Gregory, de Kruif, John, Huber, Reid, Mayes, Patrick A., Throsby, Mark

“…Immune checkpoint inhibitors demonstrate clinical activity in many tumor types, however, only a fraction of patients benefit. Combining CD137 agonists with…”
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MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis by van Loo, Pieter Fokko, Hangalapura, Basav N, Thordardottir, Soley, Gibbins, John D, Veninga, Henrike, Hendriks, Linda J A, Kramer, Arjen, Roovers, Rob C, Leenders, Marij, de Kruif, John, Doornbos, Robert P, Sirulnik, Andres, Throsby, Mark, Logtenberg, Ton, Dolstra, Harry, Bakker, Alexander B H

“…: We report the characterization of MCLA-117, a novel T cell-redirecting antibody for acute myeloid leukaemia (AML) treatment targeting CD3 on T cells and…”
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The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries by Kramer, R. Arjen, Marissen, Wilfred E., Goudsmit, Jaap, Visser, Therese J., Clijsters‐Van der Horst, Marieke, Bakker, Arjen Q., de Jong, Maureen, Jongeneelen, Mandy, Thijsse, Sandra, Backus, Harold H. J., Rice, Amy B., Weldon, William C., Rupprecht, Charles E., Dietzschold, Bernhard, Bakker, Alexander B. H., de Kruif, John

“…Antibody phage display technology was used to identify human monoclonal antibodies that neutralize rabies virus (RV). A phage repertoire was constructed using…”
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Cutting Edge: Ly-49D and Ly-49H Associate with Mouse DAP12 and Form Activating Receptors by Smith, Kathleen M, Wu, Jun, Bakker, Alexander B. H, Phillips, Joseph H, Lanier, Lewis L

“…Several members of the Ly-49 receptor family inhibit NK cell-mediated lysis of targets expressing appropriate MHC class I molecules. Ly-49D and Ly-49H, two…”
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A proteomic approach to tumour target identification using phage display, affinity purification and mass spectrometry by Geuijen, Cecilia A.W., Bijl, Nora, Smit, Renate C.M., Cox, Freek, Throsby, Mark, Visser, Therèse J., Jongeneelen, Mandy A.C., Bakker, Alexander B.H., Kruisbeek, Ada M., Goudsmit, Jaap, de Kruif, John

“…Tumour-associated cell surface markers are potential targets for antibody-based therapies. We have obtained a panel of myeloid cell binding single chain…”
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C-Type Lectin-Like Molecule-1 by Bakker, Alexander B. H., van den Oudenrijn, Sonja, Bakker, Arjen Q., Feller, Nicole, van Meijer, Marja, Bia, Judith A., Jongeneelen, Mandy A. C., Visser, Therese J., Bijl, Nora, Geuijen, Cecilia A. W., Marissen, Wilfred E., Radosevic, Katarina, Throsby, Mark, Schuurhuis, Gerrit Jan, Ossenkoppele, Gert J., de Kruif, John, Goudsmit, Jaap, Kruisbeek, Ada M.

“…Acute myeloid leukemia (AML) has a poor prognosis due to treatment-resistant relapses. A humanized anti-CD33 antibody (Mylotarg) showed a limited response rate…”
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A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G 1 by De Nardis, Camilla, Hendriks, Linda J A, Poirier, Emilie, Arvinte, Tudor, Gros, Piet, Bakker, Alexander B H, de Kruif, John

“…Bispecific antibodies combine two different antigen-binding sites in a single molecule, enabling more specific targeting, novel mechanisms of action, and…”
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