Search Results - "Bakkari, Mohammed Ali"
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Characterization of cisplatin-loaded chitosan nanoparticles and rituximab-linked surfaces as target-specific injectable nano-formulations for combating cancer
Published in Scientific reports (10-01-2022)“…The present study was carried out to develop cisplatin-loaded chitosan nanoparticles (CCNP) and cisplatin-loaded chitosan nanoparticle surface linked to…”
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Formulation and evaluation of injectable dextran sulfate sodium nanoparticles as a potent antibacterial agent
Published in Scientific reports (10-05-2021)“…The purpose of this study was to develop a novel nano antibacterial formulation of dextran sulfate sodium polymer. The dextran sulfate sodium (DSS)…”
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Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals
Published in Saudi pharmaceutical journal (01-06-2023)“…The study aimed to develop cisplatin-loaded PEGylated chitosan nanoparticles. The optimal batch of cisplatin-loaded PEGylated chitosan nanoparticles had…”
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Potential bioactive secondary metabolites of Actinomycetes sp. isolated from rocky soils of the heritage village Rijal Alma, Saudi Arabia
Published in Arabian journal of chemistry (01-05-2022)“…The present study was designed to discover novel secondary antibiotic metabolites from Actinomycetes species from the soil of Rijal Almaa, Saudi Arabia. A…”
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Formulation, characterization and biological evaluation of injectable nanocrystals from stem exudate gel of Caralluma retrospiciens (Ehrenb) – Part C
Published in Arabian journal of chemistry (01-02-2022)“…The purpose of this study was to develop injectable nanocrystals (NC) from stem exudate gel (EG) from Caralluma retrospiciens (Ehrenb) using the technique of…”
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Bioactive principles in exudate gel from the leaf of Aloe fleurentiniorum, traditionally used as folkloric medicine by local people of Aridah and Fayfa mountains, Saudi Arabia
Published in Arabian journal of chemistry (01-11-2021)“…Aloe fleurentiniorum is a desert plant that is occasionally used to treat wounds by local people of Aridah and Fayfa mountains in Saudi Arabia. However,…”
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Targeted Protein-Specific Multi-Epitope-Based Vaccine Designing against Human Cytomegalovirus by Using Immunoinformatics Approaches
Published in Vaccines (Basel) (17-01-2023)“…Cytomegaloviruses are emerging pathogenic agents known to cause congenital disorders in humans. In this study, immune epitopes (CTL, B cell and HTL) were…”
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Toll-like Receptor‑4 (TLR4) Agonist-Based Intranasal Nanovaccine Delivery System for Inducing Systemic and Mucosal Immunity
Published in Molecular pharmaceutics (07-06-2021)“…Eliciting a robust immune response at mucosal sites is critical in preventing the entry of mucosal pathogens such as influenza and severe acute respiratory…”
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A Review on Asthma and Allergy: Current Understanding on Molecular Perspectives
Published in Journal of clinical medicine (27-09-2024)“…Asthma, a complex disease characterized by persistent airway inflammation, remains an urgent global health concern. We explored the critical role of allergic…”
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10
Acceptance of HPV vaccination in boys among mothers from selected churches in Accra, Ghana
Published in BMC public health (01-06-2023)“…Almost all cases of cervical and anal cancer have been linked to the human papillomavirus (HPV). However, in addition to women who develop HPV-related cervical…”
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Design and characterization of Lactotransferrin peptide-loaded dextran-docosahexaenoic acid nanoparticles: an immune modulator for hepatic damage
Published in Scientific reports (19-08-2023)“…The primary objective of this research was to create injectable delivery formulations using Lactotransferrin (LTF) peptide-loaded dextran nanoparticles coated…”
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12
Utilization of experimental design in the formulation and optimization of hyaluronic acid-based nanoemulgel loaded with a turmeric-curry leaf oil nanoemulsion for gingivitis
Published in Drug delivery (01-12-2023)“…Numerous problems affect oral health, and intensive research is focused on essential oil-based nanoemulsions that might treat prevent or these problems…”
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Production, Characterization, and In Vitro and In Vivo Studies of Nanoemulsions Containing St. John's Wort Plant Constituents and Their Potential for the Treatment of Depression
Published in Pharmaceuticals (Basel, Switzerland) (26-03-2023)“…The current project was designed to prepare an oil-in-water (oil/water) hypericin nanoemulsion using eucalyptus oil for the preparation of an oil phase with…”
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Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation
Published in Frontiers in pharmacology (07-02-2023)“…The purpose of this study was to assess the parameters of doxorubicin (DOX) loaded lipid polymer hybrid nanoparticles (LPHNs) formulation development, and then…”
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Induction of Innate and Adaptive Immune Response against Recombinant HBsAg Protein Entrapped in Docosahexaenoic Acid Nanovesicles through Biomarkers
Published in Vaccines (Basel) (01-02-2023)“…The present study focused on demonstrating the induction of humoral and cell-mediated immunity through the establishment of a cytokine network. We hypothesized…”
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Preparation and In Vitro Evaluation of Levofloxacin-Loaded Floating Tables Using Various Rate-Controlling Agents
Published in ACS omega (14-11-2023)“…Floating tablets are a new approach to extending the time a drug is in the stomach to improve therapy outcomes. Floating tablets were formulated with the drug,…”
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Design, Characterization, and Immune Augmentation of Docosahexaenoic Acid Nanovesicles as a Potential Delivery System for Recombinant HBsAg Protein
Published in Vaccines (Basel) (16-06-2022)“…Recombinant HBsAg-loaded docosahexaenoic acid nanovesicles were successfully developed, lyophilized (LRPDNV) and characterized for their physico-chemical…”
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Pathogen-mimicking vaccine delivery system designed with a bioactive polymer (inulin acetate) for robust humoral and cellular immune responses
Published in Journal of controlled release (10-09-2017)“…New and improved vaccines are needed against challenging diseases such as malaria, tuberculosis, Ebola, influenza, AIDS, and cancer. The majority of existing…”
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Site-directed non-covalent polymer-drug complexes for inflammatory bowel disease (IBD): Formulation development, characterization and pharmacological evaluation
Published in Journal of controlled release (28-11-2018)“…Inflammatory Bowel Diseases (IBD) is a debilitating condition that affects ~70,000 new people every year and has been described as “an expensive disease with…”
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Structure-based virtual screening of natural compounds as inhibitors of HCV using molecular docking and molecular dynamics simulation studies
Published in Journal of biomolecular structure & dynamics (09-12-2024)“…The hepatitis C virus (HCV), which causes hepatitis C, is a viral infection that damages the liver and causes inflammation in the liver. New potentially…”
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