Search Results - "Baker, Tracie R."
-
1
Nanoplastics impact the zebrafish (Danio rerio) transcriptome: Associated developmental and neurobehavioral consequences
Published in Environmental pollution (1987) (01-11-2020)“…Microplastics (MPs) are a ubiquitous pollutant detected not only in marine and freshwater bodies, but also in tap and bottled water worldwide. While MPs have…”
Get full text
Journal Article -
2
Adult-Onset Transcriptomic Effects of Developmental Exposure to Benzene in Zebrafish ( Danio rerio ): Evaluating a Volatile Organic Compound of Concern
Published in International journal of molecular sciences (01-11-2023)“…Urban environments are afflicted by mixtures of anthropogenic volatile organic compounds (VOCs). VOC sources that drive human exposure include vehicle exhaust,…”
Get full text
Journal Article -
3
Cisplatin-induced hair cell loss in zebrafish neuromasts is accompanied by protein nitration and Lmo4 degradation
Published in Toxicology and applied pharmacology (01-01-2021)“…Generation of reactive oxygen species, a critical factor in cisplatin-induced ototoxicity, leads to the formation of peroxynitrite, which in turn results in…”
Get full text
Journal Article -
4
Developmental Dioxin Exposure Alters the Methylome of Adult Male Zebrafish Gonads
Published in Frontiers in genetics (11-01-2019)“…2,3,7,8-Tetrachlorodibenzo- -dioxin (TCDD) is a persistent environmental toxicant and endocrine disrupting compound with reproductive and developmental effects…”
Get full text
Journal Article -
5
sox9b is required in cardiomyocytes for cardiac morphogenesis and function
Published in Scientific reports (17-09-2018)“…The high mobility group transcription factor SOX9 is expressed in stem cells, progenitor cells, and differentiated cell-types in developing and mature organs…”
Get full text
Journal Article -
6
Comparative Toxicotranscriptomics of Single Cell RNA-Seq and Conventional RNA-Seq in TCDD-Exposed Testicular Tissue
Published in Frontiers in toxicology (09-05-2022)“…In this report, we compare the outcomes and limitations of two methods of transcriptomic inquiry on adult zebrafish testes exposed to…”
Get full text
Journal Article -
7
Implications of Lead (Pb)-Induced Transcriptomic and Phenotypic Alterations in the Aged Zebrafish ( Danio rerio )
Published in Toxics (Basel) (14-10-2024)“…Lead (Pb) is a well-known neurotoxin with established adverse effects on the neurological functions of children and younger adults, including motor, learning,…”
Get full text
Journal Article -
8
Multi- and Transgenerational Effects of Developmental Exposure to Environmental Levels of PFAS and PFAS Mixture in Zebrafish (Danio rerio)
Published in Toxics (Basel) (18-06-2022)“…Per- and polyfluoroalkyl substances (PFASs) are ubiquitous in the environment and are tied to myriad health effects. Despite the phasing out of the…”
Get full text
Journal Article -
9
Using Zebrafish as a Model System for Studying the Transgenerational Effects of Dioxin
Published in Toxicological sciences (01-04-2014)Get full text
Journal Article -
10
Evaluating Phenotypic and Transcriptomic Responses Induced by Low-Level VOCs in Zebrafish: Benzene as an Example
Published in Toxics (Basel) (27-06-2022)“…Urban environments are plagued by complex mixtures of anthropogenic volatile organic compounds (VOCs), such as mixtures of benzene, toluene, ethylene, and…”
Get full text
Journal Article -
11
Developmental Phenotypic and Transcriptomic Effects of Exposure to Nanomolar Levels of 4-Nonylphenol, Triclosan, and Triclocarban in Zebrafish ( Danio rerio )
Published in Toxics (Basel) (24-01-2022)“…Triclosan, triclocarban and 4-nonylphenol are all chemicals of emerging concern found in a wide variety of consumer products that have exhibited a wide range…”
Get full text
Journal Article -
12
Construction and characterization of a sox9b transgenic reporter line
Published in The International journal of developmental biology (2014)“…The transcription factor SOX9 is a member of the SRY-related high-mobility-group box (SOX) superfamily of genes. In mammals, Sox9 plays important roles in many…”
Get full text
Journal Article -
13
Unanchored ubiquitin chains do not lead to marked alterations in gene expression in Drosophila melanogaster
Published in Biology open (2019)“…The small protein modifier ubiquitin regulates various aspects of cellular biology through its chemical conjugation onto proteins. Ubiquitination of proteins…”
Get full text
Journal Article -
14
Nonlethal detection of PFAS bioaccumulation and biomagnification within fishes in an urban- and wastewater-dominant Great Lakes watershed
Published in Environmental pollution (1987) (15-03-2023)“…Per- and polyfluoroalkyl substances (PFAS) are synthetic endocrine disruptors that are particularly stable and pervasive due to strong carbon-fluorine bonds…”
Get full text
Journal Article -
15
Using zebrafish as a model system for studying the transgenerational effects of dioxin
Published in Toxicological sciences (01-04-2014)“…2,3,7,8 Tetrachlorodibenzo-p-dioxin (TCDD) has been associated with many disease states in humans. A rising concern is that exposure early in life can lead to…”
Get full text
Journal Article -
16
Exposure of Larval Zebrafish to the Insecticide Propoxur Induced Developmental Delays that Correlate with Behavioral Abnormalities and Altered Expression of hspb9 and hspb11
Published in Toxics (Basel) (21-09-2019)“…Recent studies suggest that organophosphates and carbamates affect human fetal development, resulting in neurological and growth impairment. However, these…”
Get full text
Journal Article -
17
Toxicity of microplastic fibers containing azobenzene disperse dyes to human lung epithelial cells cultured at an air-liquid interface
Published in Journal of hazardous materials (05-12-2024)“…There is growing concern surrounding the human health effects following inhalation exposure to microplastic fibers (MPFs). MPFs can harbor chemical additives,…”
Get full text
Journal Article -
18
The phenotypic and transcriptomic effects of developmental exposure to nanomolar levels of estrone and bisphenol A in zebrafish
Published in The Science of the total environment (25-02-2021)“…Estrone and BPA are two endocrine disrupting chemicals (EDCs) that are predicted to be less potent than estrogens such as 17β-estradiol and…”
Get full text
Journal Article -
19
Early dioxin exposure causes toxic effects in adult zebrafish
Published in Toxicological sciences (01-09-2013)“…The acute effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure have been well documented in many vertebrate species. However, less is known about the…”
Get full text
Journal Article -
20
Ancestral TCDD Exposure Induces Multigenerational Histologic and Transcriptomic Alterations in Gonads of Male Zebrafish
Published in Toxicological sciences (01-08-2018)“…Abstract 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), the classic aryl hydrocarbon receptor (AhR) agonist, is a potent environmental toxicant and…”
Get full text
Journal Article