Search Results - "Baker, Ruth E."

Vertex Models of Epithelial Morphogenesis by Fletcher, Alexander G., Osterfield, Miriam, Baker, Ruth E., Shvartsman, Stanislav Y.

“…The dynamic behavior of epithelial cell sheets plays a central role during numerous developmental processes. Genetic and imaging studies of epithelial…”
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Mechanistic models versus machine learning, a fight worth fighting for the biological community? by Baker, Ruth E., Peña, Jose-Maria, Jayamohan, Jayaratnam, Jérusalem, Antoine

“…Ninety per cent of the world's data have been generated in the last 5 years (Machine learning: the power and promise of computers that learn by example. Report…”
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Mechanocellular models of epithelial morphogenesis by Fletcher, Alexander G., Cooper, Fergus, Baker, Ruth E.

“…Embryonic epithelia achieve complex morphogenetic movements, including in-plane reshaping, bending and folding, through the coordinated action and…”
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Biologically-informed neural networks guide mechanistic modeling from sparse experimental data by Lagergren, John H, Nardini, John T, Baker, Ruth E, Simpson, Matthew J, Flores, Kevin B

“…Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying…”
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Efficient Bayesian inference for mechanistic modelling with high-throughput data by Martina Perez, Simon, Sailem, Heba, Baker, Ruth E.

“…Bayesian methods are routinely used to combine experimental data with detailed mathematical models to obtain insights into physical phenomena. However, the…”
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Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells by Lei, Mingxing, Schumacher, Linus J., Lai, Yung-Chih, Juan, Wen-Tau, Yeh, Chao-Yuan, Wu, Ping, Jiang, Ting-Xin, Baker, Ruth E., Widelitz, Randall Bruce, Yang, Li, Chuong, Cheng-Ming

“…Organoids made from dissociated progenitor cells undergo tissue-like organization. This in vitro self-organization process is not identical to embryonic organ…”
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An automatic adaptive method to combine summary statistics in approximate Bayesian computation by Harrison, Jonathan U, Baker, Ruth E

“…To infer the parameters of mechanistic models with intractable likelihoods, techniques such as approximate Bayesian computation (ABC) are increasingly being…”
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Impact of implementation choices on quantitative predictions of cell-based computational models by Kursawe, Jochen, Baker, Ruth E., Fletcher, Alexander G.

“…‘Cell-based’ models provide a powerful computational tool for studying the mechanisms underlying the growth and dynamics of biological tissues in health and…”
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A random cell motility gradient downstream of FGF controls elongation of an amniote embryo by Denans, Nicolas, Little, Charles D, Francois, Paul, Bénazéraf, Bertrand, Baker, Ruth E, Pourquié, Olivier

“…Vertebrate embryos are characterized by an elongated antero-posterior (AP) body axis, which forms by progressive cell deposition from a posterior growth zone…”
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Multiscale mechanisms of cell migration during development: theory and experiment by McLennan, Rebecca, Dyson, Louise, Prather, Katherine W, Morrison, Jason A, Baker, Ruth E, Maini, Philip K, Kulesa, Paul M

“…Long-distance cell migration is an important feature of embryonic development, adult morphogenesis and cancer, yet the mechanisms that drive subpopulations of…”
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Multi-cellular rosettes in the mouse visceral endoderm facilitate the ordered migration of anterior visceral endoderm cells by Trichas, Georgios, Smith, Aaron M, White, Natalia, Wilkins, Vivienne, Watanabe, Tomoko, Moore, Abigail, Joyce, Bradley, Sugnaseelan, Jacintha, Rodriguez, Tristan A, Kay, David, Baker, Ruth E, Maini, Philip K, Srinivas, Shankar

“…The visceral endoderm (VE) is a simple epithelium that forms the outer layer of the egg-cylinder stage mouse embryo. The anterior visceral endoderm (AVE), a…”
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Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells by Plikus, Maksim V., Baker, Ruth E., Chen, Chih-Chiang, Fare, Clyde, de la Cruz, Damon, Andl, Thomas, Maini, Philip K., Millar, Sarah E., Widelitz, Randall, Chuong, Cheng-Ming

“…Stem cells cycle through active and quiescent states. Large populations of stem cells in an organ may cycle randomly or in a coordinated manner. Although stem…”
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Neural crest cells bulldoze through the microenvironment using Aquaporin 1 to stabilize filopodia by McLennan, Rebecca, McKinney, Mary C, Teddy, Jessica M, Morrison, Jason A, Kasemeier-Kulesa, Jennifer C, Ridenour, Dennis A, Manthe, Craig A, Giniunaite, Rasa, Robinson, Martin, Baker, Ruth E, Maini, Philip K, Kulesa, Paul M

“…Neural crest migration requires cells to move through an environment filled with dense extracellular matrix and mesoderm to reach targets throughout the…”
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Dynamic fibronectin assembly and remodeling by leader neural crest cells prevents jamming in collective cell migration by Martinson, William Duncan, McLennan, Rebecca, Teddy, Jessica M, McKinney, Mary C, Davidson, Lance A, Baker, Ruth E, Byrne, Helen M, Kulesa, Paul M, Maini, Philip K

“…Collective cell migration plays an essential role in vertebrate development, yet the extent to which dynamically changing microenvironments influence this…”
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Capabilities and Limitations of Tissue Size Control through Passive Mechanical Forces by Kursawe, Jochen, Brodskiy, Pavel A, Zartman, Jeremiah J, Baker, Ruth E, Fletcher, Alexander G

“…Embryogenesis is an extraordinarily robust process, exhibiting the ability to control tissue size and repair patterning defects in the face of environmental…”
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Simplified method for including spatial correlations in mean-field approximations by Markham, Deborah C, Simpson, Matthew J, Baker, Ruth E

“…Biological systems involving proliferation, migration, and death are observed across all scales. For example, they govern cellular processes such as wound…”
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Turing's model for biological pattern formation and the robustness problem by Maini, Philip K., Woolley, Thomas E., Baker, Ruth E., Gaffney, Eamonn A., Lee, S. Seirin

“…One of the fundamental questions in developmental biology is how the vast range of pattern and structure we observe in nature emerges from an almost uniformly…”
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The impact of temporal sampling resolution on parameter inference for biological transport models by Harrison, Jonathan U, Baker, Ruth E

“…Imaging data has become an essential tool to explore key biological questions at various scales, for example the motile behaviour of bacteria or the transport…”
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Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model by Mort, Richard L., Ross, Robert J. H., Hainey, Kirsten J., Harrison, Olivia J., Keighren, Margaret A., Landini, Gabriel, Baker, Ruth E., Painter, Kevin J., Jackson, Ian J., Yates, Christian A.

“…Bands of colour extending laterally from the dorsal to ventral trunk are a common feature of mouse chimeras. These stripes were originally taken as evidence of…”
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Interactions between Shh, Sostdc1 and Wnt signaling and a new feedback loop for spatial patterning of the teeth by Cho, Sung-Won, Kwak, Sungwook, Woolley, Thomas E, Lee, Min-Jung, Kim, Eun-Jung, Baker, Ruth E, Kim, Hee-Jin, Shin, Jeon-Soo, Tickle, Cheryll, Maini, Philip K, Jung, Han-Sung

“…Each vertebrate species displays specific tooth patterns in each quadrant of the jaw: the mouse has one incisor and three molars, which develop at precise…”
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