Search Results - "Bakari, M"
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Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults
Published in Clinical infectious diseases (31-12-2020)“…Abstract Background A vaccine would be an ideal tool for reducing malaria’s impact. PfSPZ Vaccine (radiation attenuated, aseptic, purified, cryopreserved…”
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Safety and Differential Antibody and T-Cell Responses to the Plasmodium falciparum Sporozoite Malaria Vaccine, PfSPZ Vaccine, by Age in Tanzanian Adults, Adolescents, Children, and Infants
Published in The American journal of tropical medicine and hygiene (01-01-2019)“…In 2016, there were more cases and deaths caused by malaria globally than in 2015. An effective vaccine would be an ideal additional tool for reducing…”
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Safety and protective efficacy of PfSPZ Vaccine administered to HIV-negative and -positive Tanzanian adults
Published in The Journal of clinical investigation (15-03-2024)“…BACKGROUNDSanaria PfSPZ Vaccine, composed of attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), protects against malaria. We conducted this clinical…”
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Population Pharmacokinetics of Antimalarial Naphthoquine in Combination with Artemisinin in Tanzanian Children and Adults: Dose Optimization
Published in Antimicrobial agents and chemotherapy (17-05-2022)“…The combination antimalarial therapy of artemisinin-naphthoquine (ART-NQ) was developed as a single-dose therapy, aiming to improve adherence relative to the…”
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Design of a Hybrid Energy System with Energy Storage for Standalone DC Microgrid Application
Published in Energies (Basel) (01-09-2021)“…This paper presents microgrid-distributed energy resources (DERs) for a rural standalone system. It is made up of a solar photovoltaic (solar PV) system,…”
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Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults
Published in The American journal of tropical medicine and hygiene (01-01-2018)“…We are using controlled human malaria infection (CHMI) by direct venous inoculation (DVI) of cryopreserved, infectious (Pf) sporozoites (SPZ) (PfSPZ Challenge)…”
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Randomized, controlled trial of a protein-calorie supplement for women coinfected with HIV-TB
Published in The international journal of tuberculosis and lung disease (01-08-2022)Get full text
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Motivations to participate in a Phase I/II HIV vaccine trial: A descriptive study from Dar es Salaam, Tanzania
Published in BMC public health (24-02-2016)“…The search for an efficacious HIV vaccine is a global priority. To date only one HIV vaccine trial (RV144) has shown modest efficacy in a phase III trial. With…”
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Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment
Published in Journal of antimicrobial chemotherapy (01-12-2014)“…To assess the effect of the major efavirenz metabolizing enzyme (CYP2B6) genotype and the effects of rifampicin co-treatment on induction of CYP3A by…”
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A double-blind placebo-controlled trial of azithromycin to reduce mortality and improve growth in high-risk young children with non-bloody diarrhoea in low resource settings: the Antibiotics for Children with Diarrhoea (ABCD) trial protocol
Published in Current controlled trials in cardiovascular medicine (13-01-2020)“…Acute diarrhoea is a common cause of illness and death among children in low- to middle-income settings. World Health Organization guidelines for the clinical…”
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High Rates of Clinical and Subclinical Tuberculosis among HIV-Infected Ambulatory Subjects in Tanzania
Published in Clinical infectious diseases (15-05-2005)“…Background We sought to determine the prevalence of active tuberculosis among ambulatory HIV-infected persons in Tanzania with CD4 cell counts of ⩾200…”
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Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4 -hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment
Published in Journal of antimicrobial chemotherapy (01-12-2014)“…To assess the effect of the major efavirenz metabolizing enzyme (CYP2B6) genotype and the effects of rifampicin co-treatment on induction of CYP3A by…”
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Disseminated tuberculosis in human immunodeficiency virus infection: ineffective immunity, polyclonal disease and high mortality
Published in The international journal of tuberculosis and lung disease (01-08-2011)“…BACKGROUND: Disseminated tuberculosis (TB) is a major cause of death in patients with the acquired immune-deficiency syndrome (AIDS), but its pathogenesis and…”
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Enhancing adherence to antiretroviral therapy at the HIV clinic in resource constrained countries; the Tanzanian experience
Published in Tropical medicine & international health (01-10-2009)“…Summary Objective To evaluate various strategies aimed at improving adherence to antiretroviral therapy (ART). Methods Patients initiated on ART at Muhimbili…”
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Completion of isoniazid preventive therapy and survival in HIV-infected, TST-positive adults in Tanzania
Published in The international journal of tuberculosis and lung disease (01-11-2011)“…SETTING: The World Health Organization recommends the use of isoniazid preventive therapy (IPT) for human immunodeficiency virus (HIV) infected patients with a…”
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Low BMI and falling BMI predict HIV-associated tuberculosis: a prospective study in Tanzania
Published in The international journal of tuberculosis and lung disease (01-11-2010)“…BACKGROUND: Low body mass index (BMI) is a known risk factor for tuberculosis (TB) in people without human immunodeficiency virus (HIV), but there are no…”
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New vaccines for the prevention of tuberculosis in human immunodeficiency virus infection [Perspectives]
Published in The international journal of tuberculosis and lung disease (01-06-2012)“…The prevention of human immunodeficiency virus (HIV) associated tuberculosis (TB) remains challenging. Several vaccines against TB have advanced to clinical…”
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Enrolment and logistical challenges in TaMoVac 01 Phase I/II HIV trial despite the completion of an earlier (HIVIS-03 trial trial) in Dar es Salaam
Published in Retrovirology (13-09-2012)“…Doc number: P153…”
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