Search Results - "Bakal, Ravindra"

QSAR, Molecular Docking, MD Simulation and MMGBSA Calculations Approaches to Recognize Concealed Pharmacophoric Features Requisite for the Optimization of ALK Tyrosine Kinase Inhibitors as Anticancer Leads by Jawarkar, Rahul D, Sharma, Praveen, Jain, Neetesh, Gandhi, Ajaykumar, Mukerjee, Nobendu, Al-Mutairi, Aamal A, Zaki, Magdi E A, Al-Hussain, Sami A, Samad, Abdul, Masand, Vijay H, Ghosh, Arabinda, Bakal, Ravindra L

“…ALK tyrosine kinase ALK TK is an important target in the development of anticancer drugs. In the present work, we have performed a QSAR analysis on a dataset…”
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QSAR Evaluations to Unravel the Structural Features in Lysine-Specific Histone Demethylase 1A Inhibitors for Novel Anticancer Lead Development Supported by Molecular Docking, MD Simulation and MMGBSA by Jawarkar, Rahul D., Bakal, Ravindra L., Mukherjee, Nobendu, Ghosh, Arabinda, Zaki, Magdi E. A., AL-Hussain, Sami A., Al-Mutairi, Aamal A., Samad, Abdul, Gandhi, Ajaykumar, Masand, Vijay H.

“…Using 84 structurally diverse and experimentally validated LSD1/KDM1A inhibitors, quantitative structure–activity relationship (QSAR) models were built by OECD…”
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Repurposing food molecules as a potential BACE1 inhibitor for Alzheimer’s disease by Mukerjee, Nobendu, Das, Anubhab, Jawarkar, Rahul D., Maitra, Swastika, Das, Padmashree, Castrosanto, Melvin A., Paul, Soumyadip, Samad, Abdul, Zaki, Magdi E. A., Al-Hussain, Sami A., Masand, Vijay H., Hasan, Mohammad Mehedi, Bukhari, Syed Nasir Abbas, Perveen, Asma, Alghamdi, Badrah S., Alexiou, Athanasios, Kamal, Mohammad Amjad, Dey, Abhijit, Malik, Sumira, Bakal, Ravindra L., Abuzenadah, Adel Mohammad, Ghosh, Arabinda, Md Ashraf, Ghulam

“…Alzheimer’s disease (AD) is a severe neurodegenerative disorder of the brain that manifests as dementia, disorientation, difficulty in speech, and progressive…”
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Identification of potent aldose reductase inhibitors as antidiabetic (Anti-hyperglycemic) agents using QSAR based virtual Screening, molecular Docking, MD simulation and MMGBSA approaches by Bakal, Ravindra L., Jawarkar, Rahul D., Manwar, J.V., Jaiswal, Minal S., Ghosh, Arabinda, Gandhi, Ajaykumar, Zaki, Magdi E.A., Al-Hussain, Sami, Samad, Abdul, Masand, Vijay H., Mukerjee, Nobendu, Nasir Abbas Bukhari, Syed, Sharma, Praveen, Lewaa, Israa

“…The aldose reductase (AR) enzyme is an important target enzyme in the development of therapeutics against hyperglycaemia induced health complications such as…”
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Ultrasound-Assisted Facile Synthesis of Nanostructured Hybrid Vesicle for the Nasal Delivery of Indomethacin: Response Surface Optimization, Microstructure, and Stability by Patil, Suraj S., Kumbhar, Dipak D., Manwar, Jagdish V., Jadhao, Rajesh G., Bakal, Ravindra L., Wakode, Sharad

“…This work is devoted to design a novel nanostructured hybrid vesicle (NHV) made of lecithin and an acrylate/C10-C30 alkyl acrylate for the nasal delivery of a…”
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Role of phytochemicals as potential radioprotectants by Chavhan, Sarin A., Bakal, Ravindra L., Jawarkar, Rahul D., Gandhi, Roshani P., Chandak, Mayuri P., Lewaa, Israa

“…Background Ionizing radiations causes harm to living organisms and the rapid technological progress has increased human exposure to ionizing radiations…”
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Exploring the use of herbal drugs and advanced supporting techniques for wound healing by Jain, Chetan M., Bakal, Ravindra L., Burange, Prashant J., Kochar, Nitin I., Manwar, Jagdish V., Jawarkar, Rahul D., Jaiswal, Minal S., Lewaa, Israa

“…Background A wound may define as an interruption within the continuity of the epithelial lining of the skin or mucosa that occurs as a result of physical or…”
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Development of a Single Ion Pair HPLC Method for Analysis of Terbinafine, Ofloxacin, Ornidazole, Clobetasol, and Two Preservatives in a Cream Formulation: Application to In Vitro Drug Release in Topical Simulated Media-Phosphate Buffer Through Rat Skin by Dewani, Anil P, Bakal, Ravindra L, Kokate, Pranjali G, Chandewar, Anil V, Patra, Srdhanjali

“…Present work reports an HPLC method with UV detection for quantification of terbinafine, ofloxacin, ornidazole, and clobetasol in a cream formulation along…”
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Modulation of serratiopeptidase transdermal patch by lipid-based transfersomes by Shende, Pravin K., Bakal, Ravindra L., Gaud, R.S., Batheja, Kiran N., Kawadiwale, Madhugandha S.

“…Serratiopeptidase is a proteolytic enzyme obtained from serratia marcescens strain E-15 and used as anti-inflammatory and analgesic drug. Serratiopeptidase…”
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Response surface based co-optimization of release kinetics and mucoadhesive strength for an oral mucoadhesive tablet of cefixime trihydrate by Manwar, Jagdish, Kumbhar, Dipak D., Bakal, Ravindra, Baviskar, Swati, Manmode, Rahul

“…[Display omitted] •We designed a robust matrix system for an oral delivery of cefixime trihydrate.•Carbopol (CP) 974P was main variable influencing…”
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Nitric Oxide and the Gastrointestinal Tract by Kochar, Nitin I., Chandewal, Anil V., Bakal, Ravindra L., Kochar, Priya N.

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Response surface based optimization of system variables for liquid chromatographic analysis of candesartan cilexetil by Manwar, Jagdish V., Vispute, Snehal S., Kumbhar, Dipak D., Manmode, Rahul S., Bakal, Ravindra L., Jadhao, Rajesh G., Jogdand, Shreyas D.

“…A statistical optimization method was successfully employed to study the effect of system variables on the chromatographic analysis of candesartan cilexetil…”
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Effect of inclusion complexation of meloxicam with β-cyclodextrin- and β-cyclodextrin-based nanosponges on solubility, in vitro release and stability studies by Shende, Pravin K., Gaud, R.S., Bakal, Ravindra, Patil, Dipmala

“…Mechanisms of inclusion complexation [Display omitted] •Pyromellitic dianhydride (PMDA) cross-linked β-cyclodextrin-based nanosponges acted as carriers to…”
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