Search Results - "Bajpai, Apratim"

Microskeletal stiffness promotes aortic aneurysm by sustaining pathological vascular smooth muscle cell mechanosensation via Piezo1 by Qian, Weiyi, Hadi, Tarik, Silvestro, Michele, Ma, Xiao, Rivera, Cristobal F., Bajpai, Apratim, Li, Rui, Zhang, Zijing, Qu, Hengdong, Tellaoui, Rayan Sleiman, Corsica, Annanina, Zias, Ariadne L., Garg, Karan, Maldonado, Thomas, Ramkhelawon, Bhama, Chen, Weiqiang

“…Mechanical overload of the vascular wall is a pathological hallmark of life-threatening abdominal aortic aneurysms (AAA). However, how this mechanical stress…”
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Single-Cell Analysis of Contractile Forces in iPSC-Derived Cardiomyocytes: Paving the Way for Precision Medicine in Cardiovascular Disease by Turnbull, Irene C, Bajpai, Apratim, Jankowski, Katherine B, Gaitas, Angelo

“…Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) hold enormous potential in cardiac disease modeling, drug screening, and regenerative medicine…”
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The cellular mechanobiology of aging: from biology to mechanics by Bajpai, Apratim, Li, Rui, Chen, Weiqiang

“…Aging is a chronic, complicated process that leads to degenerative physical and biological changes in living organisms. Aging is associated with permanent,…”
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The Interplay Between Cell-Cell and Cell-Matrix Forces Regulates Cell Migration Dynamics by Bajpai, Apratim, Tong, Jie, Qian, Weiyi, Peng, Yansong, Chen, Weiqiang

“…Cells in vivo encounter and exert forces as they interact with the extracellular matrix (ECM) and neighboring cells during migration. These mechanical forces…”
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Probing the biophysical mechanisms underlying aging-associated decline in vascular cell mechanosensation using a novel ultrasound-tweezers system by Bajpai, Apratim, Luu, Ngoc, Qian, Weiyi, Li, Rui, Chen, Weiqiang

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Surface decoration of biomimetic Wnt5a ligands promotes cytotoxic T-cell mechanotransduction and activation by Li, Rui, Ali, Walida, Luu, Ngoc, Bajpai, Apratim, Chen, Weiqiang

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Aging‐associated decline in vascular smooth muscle cell mechanosensation is mediated by Piezo1 channel by Luu, Ngoc, Bajpai, Apratim, Li, Rui, Park, Seojin, Noor, Mahad, Ma, Xiao, Chen, Weiqiang

“…Aging of the vasculature is associated with detrimental changes in vascular smooth muscle cell (VSMC) mechanosensitivity to extrinsic forces in their…”
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Featured Cover by Luu, Ngoc, Bajpai, Apratim, Li, Rui, Park, Seojin, Noor, Mahad, Ma, Xiao, Chen, Weiqiang

“…Cover legend: The cover image is based on the Research Article Aging‐associated decline in vascular smooth muscle cell mechanosensation is mediated by Piezo1…”
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Integrated Micromechanical System for Investigating the Mechanisms of Vascular Cell Mechanobiology by Bajpai, Apratim

“…Vascular cell mechanobiology is an interdisciplinary area of research focusing on the interaction between vascular cells and the external inputs that the cells…”
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Energy‐Mediated Machinery Drives Cellular Mechanical Allostasis by Wang, Qianbin, Qian, Weiyi, Xu, Xiaoyu, Bajpai, Apratim, Guan, Kevin, Zhang, Zijing, Chen, Roy, Flamini, Vittoria, Chen, Weiqiang

“…Allostasis is a fundamental biological process through which living organisms achieve stability via physiological or behavioral changes to protect against…”
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Cellogram: On-the-Fly Traction Force Microscopy by Lendenmann, Tobias, Schneider, Teseo, Dumas, Jérémie, Tarini, Marco, Giampietro, Costanza, Bajpai, Apratim, Chen, Weiqiang, Gerber, Julia, Poulikakos, Dimos, Ferrari, Aldo, Panozzo, Daniele

“…Traction force microscopy (TFM) derives maps of cell-generated forces, typically in the nanonewton range, transmitted to the extracellular environment upon…”
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Nanotopographic Regulation of Human Mesenchymal Stem Cell Osteogenesis by Qian, Weiyi, Gong, Lanqi, Cui, Xin, Zhang, Zijing, Bajpai, Apratim, Liu, Chao, Castillo, Alesha B, Teo, Jeremy C. M, Chen, Weiqiang

“…Mesenchymal stem cell (MSC) differentiation can be manipulated by nanotopographic interface providing a unique strategy to engineering stem cell therapy and…”
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Mechanical Forces Regulate Asymmetric Vascular Cell Alignment by Cui, Xin, Tong, Jie, Yau, Jimmy, Bajpai, Apratim, Yang, Jing, Peng, Yansong, Singh, Mrinalini, Qian, Weiyi, Ma, Xiao, Chen, Weiqiang

“…Mechanical forces between cells and their microenvironment critically regulate the asymmetric morphogenesis and physiological functions in vascular systems…”
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Surface presentation of the noncanonical Wnt5a motif to cytotoxic CD8 + T-cells promotes their mechanotransduction and activation by Li, Rui, Ali, Walida, Ma, Chao, Bajpai, Apratim, Luu, Ngoc, Varshney, Aarushi, Rowe, Camden Riley, Chen, Weiqiang

“…We report here strategic functionalization of the Wnt5a mimetic peptide ligand Foxy5 on a polydimethylsiloxane elastomer substrate to enhance the…”
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