Search Results - "Bajinting, Adam"
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Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model
Published in Scientific reports (02-03-2020)“…The development and physiologic role of small intestine (SI) vasculature is poorly studied. This is partly due to a lack of targetable, organ-specific markers…”
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Recombinant expression in E. coli of human FGFR2 with its transmembrane and extracellular domains
Published in PeerJ (San Francisco, CA) (29-06-2017)“…Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases containing three domains: an extracellular receptor domain, a single…”
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A Detailed Protocol for Large-scale Recombinant Expression and Validation of Human FGFR2 with Its Transmembrane and Extracellular Domains in Escherichia coli
Published in Bio-protocol (05-06-2019)“…Receptor tyrosine kinases (RTKs) are an important class of transmembrane receptors that mediate some of the most crucial biochemical pathways essential to the…”
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EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis
Published in PloS one (15-09-2020)“…Background Short bowel syndrome (SBS) results from significant loss of small intestinal length. In response to this loss, adaptation occurs, with Epidermal…”
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Antibiotic-driven intestinal dysbiosis in pediatric short bowel syndrome is associated with persistently altered microbiome functions and gut-derived bloodstream infections
Published in Gut microbes (01-01-2021)“…Surgical removal of the intestine, lifesaving in catastrophic gastrointestinal disorders of infancy, can result in a form of intestinal failure known as short…”
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Perioperative considerations in nonagenarians
Published in Surgery open science (01-10-2020)“…The nation's aging population presents novel perioperative challenges. Potential benefits of operative interventions must be scrutinized in relation to…”
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Structural studies of full-length receptor tyrosine kinases and their implications for drug design
Published in Advances in protein chemistry and structural biology (2021)“…Receptor tyrosine kinases (RTKs) are important drug targets for cancer and immunological disorders. Crystal structures of individual RTK domains have…”
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To operate or not to operate? Assessing NSQIP surgical outcomes in trisomy 18 patients
Published in Journal of pediatric surgery (01-03-2021)“…Trisomy 18 is associated with a wide range of potentially fatal congenital conditions. Historically, clinical attitudes on treatment have been ambiguous, with…”
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Extracellular Matrix Facilitates Adaptation to Small Bowel Resection
Published in Pediatrics (Evanston) (01-07-2020)Get full text
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Predictors of length of stay for simple gastroschisis: analysis of ACS NSQIP-P database
Published in Pediatric surgery international (01-10-2022)“…Purpose We aimed to assess predictors of length of stay for simple gastroschisis utilizing the NSQIP-Pediatric Database. Methods The NSQIP-P Participant Use…”
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Small Bowel Resection Alters Mucus Barrier Via Changes in the Gut Microbiota
Published in Pediatrics (Evanston) (01-03-2021)Get full text
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Su1091 – Subepithelial Microrna Expression During Adaptation to Massive Small Bowel Resection
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2019)Get full text
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An Unspoken Truth: To Operate or Not to Operate? Assessing NSQIP Surgical Outcomes in Trisomy 18 Patients
Published in Journal of the American College of Surgeons (01-10-2019)Get full text
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14
Adaptation of extracellular matrix to massive small bowel resection in mice
Published in Journal of pediatric surgery (01-06-2020)“…Extracellular matrix (ECM) affects cell behavior, and vice versa. How ECM changes after small bowel resection (SBR) to support adaptive cellular processes has…”
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Multicenter retrospective comparison of spontaneous intestinal perforation outcomes between primary peritoneal drain and primary laparotomy
Published in Journal of pediatric surgery (01-07-2020)“…The purpose of our study was to compare outcomes of infants with spontaneous intestinal perforation (SIP) treated with primary peritoneal drain versus primary…”
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EGFR in enterocytes endothelium and HIF1[alpha] in enterocytes are dispensable for massive small bowel resection induced angiogenesis
Published in PloS one (15-09-2020)“…Background Short bowel syndrome (SBS) results from significant loss of small intestinal length. In response to this loss, adaptation occurs, with Epidermal…”
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Index Admission Cholecystectomy and Recurrence of Pediatric Gallstone Pancreatitis: Multicenter Cohort Analysis
Published in Journal of the American College of Surgeons (01-03-2022)“…We aim to evaluate recurrence rates of gallstone pancreatitis in children undergoing early vs interval cholecystectomy. A multicenter, retrospective review of…”
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Pneumomediastinum: A Rare Presentation of Inflicted Injuries in Infants
Published in Journal of pediatric intensive care (01-06-2022)“…Abstract Reports of incidental pneumomediastinum in infants secondary to inflicted trauma are limited. A retrospective review of infants with pneumomediastinum…”
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Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice
Published in Cellular and molecular gastroenterology and hepatology (01-01-2019)“…Background & AimsThe small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut…”
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Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in MiceSummary
Published in Cellular and molecular gastroenterology and hepatology (01-01-2019)“…Background & Aims: The small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut…”
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