Search Results - "Baji, Ádám"

Dihydrotestosterone-based A-ring-fused pyridines: Microwave-assisted synthesis and biological evaluation in prostate cancer cells compared to structurally related quinolines by Kiss, Márton A., Peřina, Miroslav, Bereczki, Laura, Baji, Ádám, Bělíček, Jakub, Jorda, Radek, Frank, Éva

“…Dysfunction of the androgen receptor (AR) signalling axis plays a pivotal role in the development and progression of prostate cancer (PCa). Steroidal and…”
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Synthesis of dihydrotestosterone derivatives modified in the A-ring with (hetero)arylidene, pyrazolo[1,5-a]pyrimidine and triazolo[1,5-a]pyrimidine moieties and their targeting of the androgen receptor in prostate cancer by Kiss, Márton A., Peřina, Miroslav, Bazgier, Václav, May, Nóra V., Baji, Ádám, Jorda, Radek, Frank, Éva

“…[Display omitted] •Novel 2-arylidene derivatives of 5α-dihydrotestosterone have been synthesized.•Heterocyclizations of the α,β-enones were performed with…”
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Androstano-arylpyrimidines: Novel small molecule inhibitors of MDR1 for sensitizing multidrug-resistant breast cancer cells by Gopisetty, Mohana Krishna, Adamecz, Dóra Izabella, Nagy, Ferenc István, Baji, Ádám, Lathira, Vasiliki, Szabó, Márton Richárd, Gáspár, Renáta, Csont, Tamás, Frank, Éva, Kiricsi, Mónika

“…•all of the acetylated androstano-arylpyrimidines inhibited MDR1 efflux activity.•inhibition of MDR1 efflux was not associated with the regulation of its…”
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Semi-Synthetic Dihydrotestosterone Derivatives Modulate Inherent Multidrug Resistance and Sensitize Colon Cancer Cells to Chemotherapy by Nagy, Ferenc István, Adamecz, Dóra Izabella, Baji, Ádám, Kiricsi, Ágnes, Huliák, Ildikó, Rónavári, Andrea, Kónya, Zoltán, Frank, Éva, Gopisetty, Mohana Krishna, Kiricsi, Mónika

“…Multidrug resistance (MDR) is a serious hurdle to successful cancer therapy. Here, we examined the efficiency of novel semi-synthetic dihydrotestosterone…”
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Multicomponent access to androstano-arylpyrimidines under microwave conditions and evaluation of their anti-cancer activity in vitro by Baji, Ádám, Kiss, Tamás, Wölfling, János, Kovács, Dávid, Igaz, Nóra, Gopisetty, Mohana Krishna, Kiricsi, Mónika, Frank, Éva

“…[Display omitted] •Microwave-assisted one-pot multicomponent reactions were carried out.•Pyrimidine heteroring was introduced into rings D and A of the sterane…”
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Investigation of pH and substituent effects on the distribution ratio of novel steroidal ring D- and A-fused arylpyrazole regioisomers and evaluation of their cell-growth inhibitory effects in vitro by Baji, Ádám, Kovács, Ferenc, Mótyán, Gergő, Schneider, Gyula, Wölfling, János, Sinka, Izabella, Zupkó, István, Ocsovszki, Imre, Frank, Éva

“…[Display omitted] •Knorr reactions of steroidal β-ketoaldehydes with arylhydrazines were carried out.•Pyrazole heteroring was introduced into rings D and A of…”
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Regio- and stereoselective synthesis of pregnane-fused isoxazolines by nitril-oxide/alkene 1,3-dipolar cycloaddition and an evaluation of their cell-growth inhibitory effect in vitro by Motyan, Gergo, Baji, Adam, Zupko, Istvan, Frank, Eva

“…Efficient syntheses of some pregnane-fused isoxazolines from 16-dehydropregnenolone acetate with different arylnitrile oxides were carried out by 1,3-dipolar…”
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Microwave-Assisted Synthesis, Proton Dissociation Processes, and Anticancer Evaluation of Novel D-Ring-Fused Steroidal 5-Amino-1-Arylpyrazoles by Mótyán, Gergő, Baji, Ádám, Marć, Małgorzata Anna, Gopisetty, Mohana Krishna, Adamecz, Dóra I., Kiricsi, Mónika, Enyedy, Éva A., Frank, Éva

“…Taking into account the pharmacological relevance of heterocycle-fused natural steroids, the objective of the current study was to develop a multistep reaction…”
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Efficient approach to novel 1α-triazolyl-5α-androstane derivatives as potent antiproliferative agents by Kádár, Zalán, Baji, Ádám, Zupkó, István, Bartók, Tibor, Wölfling, János, Frank, Éva

“…Stereoselective 1,4-Michael addition of azoimide to 17β-acetoxy-5α-adrost-1-en-3-one was carried out to furnish a 1α-azido-3-ketone, which was reduced to give…”
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