Search Results - "Bajgar, Adam"

Extracellular adenosine modulates host-pathogen interactions through regulation of systemic metabolism during immune response in Drosophila by Bajgar, Adam, Dolezal, Tomas

“…Phagocytosis by hemocytes, Drosophila macrophages, is essential for resistance to Streptococcus pneumoniae in adult flies. Activated macrophages require an…”
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On the origin of the functional versatility of macrophages by Bajgar, Adam, Krejčová, Gabriela

“…Macrophages represent the most functionally versatile cells in the animal body. In addition to recognizing and destroying pathogens, macrophages remove…”
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Extracellular adenosine mediates a systemic metabolic switch during immune response by Bajgar, Adam, Kucerova, Katerina, Jonatova, Lucie, Tomcala, Ales, Schneedorferova, Ivana, Okrouhlik, Jan, Dolezal, Tomas

“…Immune defense is energetically costly, and thus an effective response requires metabolic adaptation of the organism to reallocate energy from storage, growth,…”
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Autonomous regulation of the insect gut by circadian genes acting downstream of juvenile hormone signaling by Bajgar, Adam, Jindra, Marek, Dolezel, David

“…In temperate regions, the shortening day length informs many insect species to prepare for winter by inducing diapause. The adult diapause of the linden bug,…”
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Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense by Krejčová, Gabriela, Danielová, Adéla, Nedbalová, Pavla, Kazek, Michalina, Strych, Lukáš, Chawla, Geetanjali, Tennessen, Jason M, Lieskovská, Jaroslava, Jindra, Marek, Doležal, Tomáš, Bajgar, Adam

“…Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory…”
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The relationships among MAOA, COMT Val158Met, and 5‐HTTLPR polymorphisms, newborn stress reactivity, and infant temperament by Bajgarova, Zdenka, Bajgar, Adam

“…Introduction Variance in hypothalamic–pituitary–adrenal (HPA) axis reactivity is considered to be one of the sources of differences in infant temperament. The…”
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Glucose and trehalose metabolism through the cyclic pentose phosphate pathway shapes pathogen resistance and host protection in Drosophila by Kazek, Michalina, Chodáková, Lenka, Lehr, Katharina, Strych, Lukáš, Nedbalová, Pavla, McMullen, Ellen, Bajgar, Adam, Opekar, Stanislav, Šimek, Petr, Moos, Martin, Doležal, Tomáš

“…Activation of immune cells requires the remodeling of cell metabolism in order to support immune function. We study these metabolic changes through the…”
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Endocrine regulation of non-circadian behavior of circadian genes in insect gut by Bajgar, Adam, Dolezel, David, Hodkova, Magdalena

“…•Endocrine system strongly affected basal levels of circadian gene transcripts in the gut.•The corpus allatum (CA) was responsible for high level of Pdp1iso1…”
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Polarization of Macrophages in Insects: Opening Gates for Immuno-Metabolic Research by Bajgar, Adam, Krejčová, Gabriela, Doležal, Tomáš

“…Insulin resistance and cachexia represent severe metabolic syndromes accompanying a variety of human pathological states, from life-threatening cancer and…”
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Functional Molecular Analysis of a Circadian Clock Gene timeless Promoter from the Drosophilid Fly Chymomyza costata by Kobelková, Alena, Bajgar, Adam, Dolezel, David

“…The circadian transcription of the tim gene is tightly regulated by the protein complex dCLK/CYC, which directly interacts with a series of closely spaced…”
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The people behind the papers - Gabriela Krejčová and Adam Bajgar

“…Macrophages maintain tissue homeostasis by removing old, damaged and apoptotic cells. During metamorphosis, the fruit fly larval fat body undergoes cell death…”
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Molecular regulations of metabolism during immune response in insects by Dolezal, Tomas, Krejcova, Gabriela, Bajgar, Adam, Nedbalova, Pavla, Strasser, Paul

“…Mounting an immune response is an energy-consuming process. Activating immune functions requires the synthesis of many new molecules and the undertaking of…”
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Juvenile hormone signaling during reproduction and development of the linden bug, Pyrrhocoris apterus by Smykal, Vlastimil, Bajgar, Adam, Provaznik, Jan, Fexova, Silvie, Buricova, Marcela, Takaki, Keiko, Hodkova, Magdalena, Jindra, Marek, Dolezel, David

“…Juvenile hormone (JH), a sesquiterpenoid produced by the insect corpus allatum gland (CA), prevents metamorphosis in larvae and stimulates vitellogenesis in…”
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Macrophages play a nutritive role in post-metamorphic maturation in Drosophila by Krejčová, Gabriela, Danielová, Adéla, Sehadová, Hana, Dyčka, Filip, Kubásek, Jiří, Moos, Martin, Bajgar, Adam

“…In the body of multicellular organisms, macrophages play an indispensable role in maintaining tissue homeostasis by removing old, apoptotic and damaged cells…”
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Inhibition of mevalonate pathway by macrophage‐specific delivery of atorvastatin prevents their pro‐inflammatory polarisation by Krejčová, Gabriela, Ruphuy, Gabriela, Šalamúnová, Petra, Sonntag, Erik, Štěpánek, František, Bajgar, Adam

“…Adjustment of the cellular metabolism of pro‐inflammatory macrophages is essential for their bactericidal function; however, it underlies the development of…”
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Macrophage‐derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection by Krejčová, Gabriela, Morgantini, Cecilia, Zemanová, Helena, Lauschke, Volker M, Kovářová, Julie, Kubásek, Jiří, Nedbalová, Pavla, Kamps‐Hughes, Nick, Moos, Martin, Aouadi, Myriam, Doležal, Tomáš, Bajgar, Adam

“…The immune response is an energy‐demanding process that must be coordinated with systemic metabolic changes redirecting nutrients from stores to the immune…”
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Yeast glucan particles enable intracellular protein delivery in Drosophila without compromising the immune system by Bajgar, Adam, Saloň, Ivan, Krejčová, Gabriela, DoleŽal, Tomáš, Jindra, Marek, Štěpánek, František

“…Glucan particles derived from yeast have been recently proposed as potential drug delivery carriers. Here, we demonstrate the potential of glucan particles for…”
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Corrigendum to “Endocrine regulation of non-circadian behavior of circadian genes in insect gut” [J. Insect Physiol. 59 (2013) 881–886] by Bajgar, Adam, Dolezel, David, Hodkova, Magdalena

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Magnetic Yeast Glucan Particles for Antibody-Free Separation of Viable Macrophages from Drosophila melanogaster by Krejčová, Gabriela, Saloň, Ivan, Klimša, Vojtěch, Ulbrich, Pavel, Aysan, Ayse Beyza, Bajgar, Adam, Štěpánek, František

“…Currently available methods for cell separation are generally based on fluorescent labeling using either endogenously expressed fluorescent markers or the…”
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Extracellular Adenosine Mediates a Systemic Metabolic Switch during Immune Response: e1002135 by Bajgar, Adam, Kucerova, Katerina, Jonatova, Lucie, Tomcala, Ales, Schneedorferova, Ivana, Okrouhlik, Jan, Dolezal, Tomas

“…Immune defense is energetically costly, and thus an effective response requires metabolic adaptation of the organism to reallocate energy from storage, growth,…”
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