Search Results - "Bajaj, Teena"
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Crystal structure of the kinase domain of a receptor tyrosine kinase from a choanoflagellate, Monosiga brevicollis
Published in PloS one (13-06-2023)“…Genomic analysis of the unicellular choanoflagellate, Monosiga brevicollis (MB), revealed the remarkable presence of cell signaling and adhesion protein…”
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Elevated Serum SIRT 2 May Differentiate Parkinson's Disease From Atypical Parkinsonian Syndromes
Published in Frontiers in molecular neuroscience (12-06-2019)“…Atypical Parkinson syndromes (APSs) often have symptoms that overlap with those of Parkinson's disease (PD), especially early in the disease, making these…”
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3
Meta-Analysis of the Expansion in the Field of Structural Biology of ABC Transporters
Published in Biodesign research (2022)“…ABC transporters are molecular machines which power the solute transport using ATP hydrolysis. The structural biology of ABC transporters has been exploding…”
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4
Developing drugs against essential proteins of SARS-CoV-2 for the treatment of COVID-19
Published in Biophysical journal (11-02-2022)Get full text
Journal Article -
5
Introducing Chemically Modified Nucleotides to Improve mRNA-Based Therapeutics
Published in Biophysical journal (12-02-2021)Get full text
Journal Article -
6
Crystal structure of the kinase domain of a receptor tyrosine kinase from a choanoflagellate, Monosiga brevicollis
Published in PloS one (13-06-2023)“…Genomic analysis of the unicellular choanoflagellate,Monosiga brevicollis(MB), revealed the remarkable presence of cell signaling and adhesion protein domains…”
Get full text
Journal Article -
7
Discovery of Small Molecule Drugs Against Crucial Proteins, Papain-Like Protease (PLpro) and Non-Structural Protein 15 (Nsp15), From SARS-CoV-2 Virus
Published 01-01-2024“…The emergence and rapid spread of the severe acute respiratory syndrome coronavirus 2, SARS-CoV-2 (SCoV-2) caused catastrophic levels of morbidity in the world…”
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Dissertation -
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Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication
Published in RSC advances (09-06-2023)“…The papain-like protease (PLpro) plays a critical role in SARS-CoV-2 (SCoV-2) pathogenesis and is essential for viral replication and for allowing the virus to…”
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Journal Article -
9
Serum Mortalin Correlated with α-Synuclein as Serum Markers in Parkinson’s Disease: A Pilot Study
Published in Neuromolecular medicine (01-03-2018)“…Mortalin, a mitochondrial chaperone, plays a crucial role in reducing toxicity of Lewy bodies. Earlier studies had reported that Mortalin level gets…”
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10
A covalent inhibitor targeting the papain-like protease from SARS-CoV-2 inhibits viral replication
Published in RSC advances (03-04-2023)“…Covalent inhibitors of the papain-like protease (PLpro) from SARS-CoV-2 have great potential as antivirals, but their non-specific reactivity with thiols has…”
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Journal Article -
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Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV‑2
Published in ACS infectious diseases (13-08-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has emerged as a major global health…”
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Journal Article