Search Results - "Bairwa, Khemraj"

Pharmaceutical perspective on bioactives from Alstonia scholaris: ethnomedicinal knowledge, phytochemistry, clinical status, patent space, and future directions by Pandey, Komal, Shevkar, Chaitrali, Bairwa, Khemraj, Kate, Abhijeet S.

“…Alstonia scholaris (L.) R. Br (Apocynaceae), a tropical tree native to Indian subcontinent, Australasia, and Malay Peninsula is well documented in Traditional…”
Get full text

Leveraging Superficially Porous Particle Technology to Develop High-Throughput HPLC Methods for Small-Molecule Drug Discovery by Tellakula, Nancharaiah, Guna, Mallikarjuna, Das, Mitalee, Bane, Vaishali, Chauthe, Siddheshwar Kisan, Mathur, Arvind, Bagadi, Muralidhararao, Bairwa, Khemraj, Roy, Amrita

“…Superficially porous particle (SPP) columns have gained considerable momentum over fully porous particle (FPP) columns among many chromatographers. However,…”
Get full text

Development and optimisation of 3-Acetyl-11-keto-β-boswellic acid loaded poly-lactic-co-glycolic acid-nanoparticles with enhanced oral bioavailability and in-vivo anti-inflammatory activity in rats by Bairwa, Khemraj, Jachak, Sanjay Madhukar

“…Objectives 3‐Acetyl‐11‐keto‐β‐boswellic acid (AKBA) is a potent anti‐inflammatory compound of Boswellia serrata. However, anti‐inflammatory activity of AKBA is…”
Get full text

Nanoparticle formulation of 11-keto-β-boswellic acid (KBA): anti-inflammatory activity and in vivo pharmacokinetics by Bairwa, Khemraj, Jachak, Sanjay Madhukar

“…Context: The oleo-gum-resin of Boswellia serrata Roxb. (Burseraceae) is widely used for the treatment of inflammatory diseases such as osteoarthritis,…”
Get full text

Anti-inflammatory potential of a lipid-based formulation of a rotenoid-rich fraction prepared from Boerhavia diffusa by Bairwa, Khemraj, Jachak, Sanjay Madhukar

“…Boerhavia diffusa L. (Nyctaginaceae) roots are used in Ayurveda for treating inflammatory diseases. Generally poor oral bioavailability is a major problem…”
Get more information

Herbal nanomedicines: Recent advancements, challenges, opportunities and regulatory overview by Teja, Parusu Kavya, Mithiya, Jinal, Kate, Abhijeet S., Bairwa, Khemraj, Chauthe, Siddheshwar K

“…Herbal Nano Medicines (HNMs) are nano-sized medicine containing herbal drugs as extracts, enriched fractions or biomarker constituents. HNMs have certain…”
Get full text

Development and optimisation of 3-Acetyl-11-keto-[beta]-boswellic acid loaded poly-lactic-co-glycolic acid-nanoparticles with enhanced oral bioavailability and in-vivo anti-inflammatory activity in rats by Bairwa, Khemraj, Jachak, Sanjay Madhukar

“…Objectives 3-Acetyl-11-keto-[beta]-boswellic acid (AKBA) is a potent anti-inflammatory compound of Boswellia serrata. However, anti-inflammatory activity of…”
Get full text

Quantitative Analysis of Boeravinones in the Roots of Boerhaavia Diffusa by UPLC/PDA by Bairwa, Khemraj, Srivastava, Amit, Jachak, Sanjay Madhukar

“…INTRODUCTION: Boerhaavia diffusa is a perennial herb belonging to Nyctaginaceae. Various classes of chemical constituents such as phenolics (boeravinones),…”
Get full text

Identification and characterisation of a novel amino acid conjugate; ergothioneine conjugate of raloxifene through in vitro and in vivo studies by Vachaspati, Prakash R., Rao, Abhijth P., Putluru, Sivaprasad, Eapen, Prasanth, Kumar, Hemantha, Landage, Raviraj, Sridhar, Srikanth, Chacko, Silvi, Bairwa, Khemraj, Sinz, Micheal, Mariappan, T. Thanga

Get full text

Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors by Grover, Jagdeep, Kumar, Vivek, Singh, Vikram, Bairwa, Khemraj, Sobhia, M. Elizabeth, Jachak, Sanjay M.

“…Nepodin and chrysophanol, isolated from Rumex nepalensis roots, showed significant cyclooxygenase (COX) inhibitory activity. To further optimize these lead…”
Get full text

High throughput and cost-effective purification of small molecules using superficially porous stationary phase columns: An environment friendly approach by Guna, Mallikarjuna, Bairwa, Khemraj, Das, Mitalee, Panda, Samikshya, Tellakula, Nancharaiah, Bagadi, Muralidhararao, Duche, Sharad, Mathur, Arvind, Roy, Amrita

“…•A solvent efficient and high throughput purification method was developed leveraging the superficially porous particle (SPP) column technology.•The results…”
Get full text

Rotenoids from Boerhaavia diffusa as Potential Anti-inflammatory Agents by Bairwa, Khemraj, Singh, Ishwari N, Roy, Somendu K, Grover, Jagdeep, Srivastava, Amit, Jachak, Sanjay M

“…Five new (2, 3, 5, 7, and 9) and four known rotenoids (1, 4, 6, and 8) were isolated from a methanol extract of Boerhaavia diffusa roots. The structures of the…”
Get full text

2'-Hydroxy flavanone derivatives as an inhibitors of pro-inflammatory mediators: Experimental and molecular docking studies by Patel, Neeraj K, Bairwa, Khemraj, Gangwal, Rahul, Jaiswal, Gaurav, Jachak, Sanjay M, Sangamwar, Abhay T, Bhutani, Kamlesh K

“…2'-Hydroxy flavanone (1) was previously isolated from Mimosa pudica (L.) whole plant and was found to exhibit anti-inflammatory effects in vitro. There are…”
Get full text

Determination of negundoside and agnuside in Vitex negundo by qNMR and method validation by Roy, Somendu Kumar, Bairwa, Khemraj, Grover, Jagdeep, Srivastava, Amit, Jachak, Sanjay Madhukar

“…Negundoside and agnuside are reported as marker constituents for standardization of Vitex negundo (V. negundo) leaves. This is the first report on…”
Get full text

Correction to Rotenoids from Boerhaavia diffusa as Potential Anti-inflammatory Agents by Bairwa, Khemraj, Singh, Ishwari N, Roy, Somendu K, Grover, Jagdeep, Srivastava, Amit, Jachak, Sanjay M

Get full text

Analysis of flavonoids and iridoids in Vitex negundo by HPLC-PDA and method validation by Roy, Somendu K, Bairwa, Khemraj, Grover, Jagdeep, Srivastava, Amit, Jachak, Sanjay M

“…The leaves of Vitex negundo have been reported to contain various bioactive constituents including iridoids and flavonoids. This is the first report on the…”
Get more information