Search Results - "Baiocchi, R."

PRMT5–PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells by Banasavadi-Siddegowda, Y K, Russell, L, Frair, E, Karkhanis, V A, Relation, T, Yoo, J Y, Zhang, J, Sif, S, Imitola, J, Baiocchi, R, Kaur, B

“…Glioblastoma (GBM) represents the most common and aggressive histologic subtype among malignant astrocytoma and is associated with poor outcomes because of…”
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The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation by Tarighat, S S, Santhanam, R, Frankhouser, D, Radomska, H S, Lai, H, Anghelina, M, Wang, H, Huang, X, Alinari, L, Walker, A, Caligiuri, M A, Croce, C M, Li, L, Garzon, R, Li, C, Baiocchi, R A, Marcucci, G

“…Changes in the enzymatic activity of protein arginine methyltransferase (PRMT) 5 have been associated with cancer; however, the protein’s role in acute myeloid…”
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A phase 1 trial of Vorinostat in combination with concurrent chemoradiation therapy in the treatment of advanced staged head and neck squamous cell carcinoma by Teknos, Theodoros N., Grecula, J., Agrawal, A., Old, M. O., Ozer, E., Carrau, R., Kang, S., Rocco, J., Blakaj, D., Diavolitsis, V., Kumar, B., Kumar, P., Pan, Q., Palettas, M., Wei, L., Baiocchi, R., Savvides, P.

“…Summary Purpose Vorinostat is a potent HDAC inhibitor that sensitizes head and neck squamous cell carcinoma (HNSCC) to cytotoxic therapy while sparing normal…”
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DARATUMUMAB AND EPOCH FOR HIV+/‐ PLASMABLASTIC LYMPHOMA: A FEASIBILITY STUDY OF THE AIDS MALIGNANCY CONSORTIUM (AMC 105) by Noy, A., Barta, S. K., Tan, C. R., Kwon, D., Baiocchi, R., Rubinstein, P., Ambinder, R.

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A SINGLE‐CENTER RETROSPECTIVE ANALYSIS OF THE TOXICITY OF HIGH‐DOSE METHOTREXATE (HDMTX) ADMINISTERED ON THE FIRST DAY OF (R)CHOP IN AGGRESSIVE NONHODGKIN LYMPHOMAS (ANHLS) by Fleming, M, Huang, Y, Dotson, E, Bond, D. A, Reneau, J, Epperla, N, Alinari, L, Brammer, J, Christian, B, Baiocchi, R. A, Maddocks, K, Sawalha, Y

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Alemtuzumab (Campath-1H) in the treatment of chronic lymphocytic leukemia by Alinari, L, Lapalombella, R, Andritsos, L, Baiocchi, R A, Lin, T S, Byrd, J C

“…Alemtuzumab (Campath-1H) is a humanized IgG1 monoclonal antibody that targets the human CD52 antigen. CD52 is expressed by a variety of lymphoid neoplasms and…”
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The Epstein-Barr Virus (EBV) in T Cell and NK Cell Lymphomas: Time for a Reassessment by Gru, A. A., Haverkos, B. H., Freud, A. G., Hastings, J., Nowacki, N. B., Barrionuevo, C., Vigil, C. E., Rochford, R., Natkunam, Y., Baiocchi, R. A., Porcu, P.

“…While Epstein-Barr virus (EBV) was initially discovered and characterized as an oncogenic virus in B cell neoplasms, it also plays a complex and multifaceted…”
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Combination of the PD‐1 inhibitor Nivolumab and Immunomodulatory Drug Lenalidomide in Relapsed Hodgkin and Large B‐cell Lymphoma: Results from a Phase I/II Study by Bond, D. A., Wei, L., Yildiz, V., Reneau, J., Sawalha, Y., Christian, B., Brammer, J., Epperla, N., Koff, J., Dendorfer, A., Yang, L., Baiocchi, R., Voorhees, T., Sigmund, A. M., Hanel, W., Shindiapina, P., Denlinger, N., Penza, S., Jaglowski, S., Bezerra, E., Alinari, L., Blum, K. A, Maddocks, K.

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PRMT5 INHIBITION RESTARTS A PRO‐APOPTOTIC PROGRAM AND CREATES VULNERABILITY TO COMBINATION TREATMENT WITH BCL‐2 INHIBITOR VENETOCLAX IN MANTLE CELL LYMPHOMA by Brown, F, Hwang, I, Sloan, S, Hinterschied, C, Helmig‐Mason, J, Long, M, Youssef, Y, Chan, W, Prouty, A, Chung, J, Zhang, Y, Chen‐Kiang, S, DiLiberto, M, Elemento, O, Sehgal, L, Alinari, L, Scherle, P, Vaddi, K, Lapalombella, R, Paik, J, Baiocchi, R. A

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CLINICAL OUTCOMES IN PATIENTS WITH EPSTEIN‐BARR VIRUS (EBV)‐POSITIVE NON‐B CELL LYMPHOMA AT THE OHIO STATE UNIVERSITY JAMES COMPREHENSIVE CANCER CENTER (OSU JAMES CCC) by Brammer, J.E., Shindiapina, P., Freud, A., Weigel, C., Oakes, C., Mishra, A., Mundy‐Bosse, B., Porcu, P., Baiocchi, R.

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CLINICAL OUTCOMES OF PATIENTS WITH T‐CELL LARGE GRANULAR LYMPHOCYTIC LEUKEMIA (T‐LGLL) AT THE OHIO STATE UNIVERSITY JAMES COMPREHENSIVE CANCER CENTER (OSU JAMES‐CCC) by Brammer, J.E., Braunstein, Z., Mishra, A., Byrd, J., Staub, A., Freud, A., Baiocchi, R., Porcu, P.

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A PHASE II TRIAL OF BRENTUXIMAB VEDOTIN (BV) AND LENALIDOMIDE (LEN) IN RELAPSED AND REFRACTORY (R/R) CUTANEOUS (CTCL) AND PERIPHERAL (PTCL) T‐CELL LYMPHOMAS: PRELIMINARY RESULTS OF A PHASE II TRIAL by William, B.M., Abbasi, A., Huang, Y., Larbi, R., Giali, R., Yang, L., Brammer, J., Grantier, C., Hoffman, C., Ayyappan, S., Baiocchi, R., Epperla, N., Christian, B., Alinari, L., Maddocks, K., Chung, C.

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Association of pre-transplantation positron emission tomography/computed tomography and outcome in mantle cell lymphoma by Cohen, J B, Hall, N C, Ruppert, A S, Jones, J A, Porcu, P, Baiocchi, R, Christian, B A, Penza, S, Benson, D M, Flynn, J, Andritsos, L A, Devine, S M, Blum, K A

“…Positron emission tomography/computed tomography (PET/CT)-positive findings before autologous SCT (auto-SCT) are associated with inferior PFS and OS in…”
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A PHASE 1B/2 STUDY OF ORAL NANATINOSTAT (N) AND VALGANCICLOVIR (VG) IN SUBJECTS WITH EPSTEIN‐BARR VIRUS (EBV)‐ASSOCIATED LYMPHOMAS by Porcu, P., Haverkos, B., Brem, E., Vallurupalli, A., Feldman, T., Alpdogan, O., Brammer, J., Bryan, L.J., Barta, S., Schriefer, A., Obrzut, S., Shen, H., Rochford, R., Baiocchi, R., Casper, C., Gutheil, J., Melink, T., Kearns, C., Burner, D., McRae, R., Daniels, P., Warren, M.S., Woody, J., Royston, I., Faller, D.

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Protein Arginine Methyltransferase-5 as a Novel Epigenetic Target in Lung Cancer by Welliver, M.X, Shilo, K, Sharma, S, Wu, X, Sif, S, Chakravarti, A, Li, C, Baiocchi, R, Otterson, G.A

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PHASE I DOSE‐ESCALATION STUDY OF VENETOCLAX PLUS BEAM FOLLOWED BY AUTOLOGOUS STEM CELL TRANSPLANT (ASCT) FOR CHEMORESISTANT, RELAPSED/REFRACTORY, OR HIGH‐RISK NON‐HODGKIN'S LYMPHOMA (NHL); PRELIMINARY RESULTS by Maakaron, J., Zhao, Q., Puto, M., Von Derau, R., Robinson, J., Brammer, J., Penza, S., Baiocchi, R., Christian, B., Maddocks, K., Saad, A., Wall, S., Benson, D., Efebera, Y., Rosko, A., Ayyappan, S., Grieselhuber, N., Vasu, S., Larkin, K., Epperla, N., Devarakonda, S., Choe, H., Chaudhry, M., Blaser, B., Blachly, J., Bhatnagar, B., Alinari, L., Mims, A., Jaglowski, S., William, B.M.

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557 PRMT5, a Novel Epigenetic Target in Lung Cancers by Otterson, G.A, Wu, X, Welliver, M, Sharma, S, Shilo, K, Hitchcock, C, Li, C, Baiocchi, R

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Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro by Carson, W E, Ross, M E, Baiocchi, R A, Marien, M J, Boiani, N, Grabstein, K, Caligiuri, M A

“…Natural killer (NK) cells are large granular lymphocytes that constitutively express functional IL-2 receptors. We have shown that recombinant human IL-15 uses…”
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P1250: EU‐SOX11CCND1: A NOVEL IMMUNOCOMPETENT MURINE MODEL OF MANTLE CELL LYMPHOMA by Brown, F., Sloan, S., Helmig‐Mason, J., Hinterschied, C., Long, M., Chan, W. K., Shindiapina, P., Leshchenko, V., Edwards, D., Vaddi, K., Scherle, P., Lapalombella, R., Alinari, L., Parekh, S., Baiocchi, R. A.

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P1244: ROLE OF SELECT T HELPER CELL MONONUCLEAR CELL SUBSETS PROMOTING EPSTEIN‐BARR VIRUS‐DRIVEN LYMPHOPROLIFERATIVE DISEASE IN THE HU‐PBL‐SCID MODEL by Ahmed, E. H., Lustberg, M., Hale, C., Sloan, S., Mao, C., Zhang, X., Ozer, H. G., Schlotter, S., Jeney, F., Chan, W., Harrington, B., Weigel, C., Alinari, L., Oakes, C., Abebe, T., Behbehani, G. K., Shindiapina, P., Caligiuri, M. A., Baiocchi, R. A.

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