Search Results - "Bains, Jaideep S."

Neurobiological Interactions Between Stress and the Endocannabinoid System by Morena, Maria, Patel, Sachin, Bains, Jaideep S, Hill, Matthew N

“…Stress affects a constellation of physiological systems in the body and evokes a rapid shift in many neurobehavioral processes. A growing body of work…”
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Stress‐induced structural and functional modifications of astrocytes—Further implicating glia in the central response to stress by Murphy‐Royal, Ciaran, Gordon, Grant R., Bains, Jaideep S.

“…An organism's response to stress requires activation of multiple brain regions. This can have long‐lasting effects on synaptic transmission and plasticity that…”
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Hypothalamic CRH neurons orchestrate complex behaviours after stress by Füzesi, Tamás, Daviu, Nuria, Wamsteeker Cusulin, Jaclyn I., Bonin, Robert P., Bains, Jaideep S.

“…All organisms possess innate behavioural and physiological programmes that ensure survival. In order to have maximum adaptive benefit, these programmes must be…”
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Social transmission and buffering of synaptic changes after stress by Sterley, Toni-Lee, Baimoukhametova, Dinara, Füzesi, Tamás, Zurek, Agnieszka A., Daviu, Nuria, Rasiah, Neilen P., Rosenegger, David, Bains, Jaideep S.

“…Stress can trigger enduring changes in neural circuits and synapses. The behavioral and hormonal consequences of stress can also be transmitted to others, but…”
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Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes by Romanov, Roman A, Zeisel, Amit, Bakker, Joanne, Girach, Fatima, Hellysaz, Arash, Tomer, Raju, Alpár, Alán, Mulder, Jan, Clotman, Frédéric, Keimpema, Erik, Hsueh, Brian, Crow, Ailey K, Martens, Henrik, Schwindling, Christian, Calvigioni, Daniela, Bains, Jaideep S, Máté, Zoltán, Szabó, Gábor, Yanagawa, Yuchio, Zhang, Ming-Dong, Rendeiro, Andre, Farlik, Matthias, Uhlén, Mathias, Wulff, Peer, Bock, Christoph, Broberger, Christian, Deisseroth, Karl, Hökfelt, Tomas, Linnarsson, Sten, Horvath, Tamas L, Harkany, Tibor

“…The hypothalamus is a brain region rich in functionally segregated neurons. Here Romanov and colleagues use single-cell RNA sequencing to distinguish 62…”
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Stress gates an astrocytic energy reservoir to impair synaptic plasticity by Murphy-Royal, Ciaran, Johnston, April D., Boyce, Andrew K. J., Diaz-Castro, Blanca, Institoris, Adam, Peringod, Govind, Zhang, Oliver, Stout, Randy F., Spray, David C., Thompson, Roger J., Khakh, Baljit S., Bains, Jaideep S., Gordon, Grant R.

“…Astrocytes support the energy demands of synaptic transmission and plasticity. Enduring changes in synaptic efficacy are highly sensitive to stress, yet…”
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Characterization of corticotropin-releasing hormone neurons in the paraventricular nucleus of the hypothalamus of Crh-IRES-Cre mutant mice by Wamsteeker Cusulin, Jaclyn I, Füzesi, Tamás, Watts, Alan G, Bains, Jaideep S

“…Corticotropin-releasing hormone (CRH)-containing neurons in the paraventricular nucleus of the hypothalamus (PVN) initiate and control neuroendocrine responses…”
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Characterization of A11 neurons projecting to the spinal cord of mice by Koblinger, Kathrin, Füzesi, Tamás, Ejdrygiewicz, Jillian, Krajacic, Aleksandra, Bains, Jaideep S, Whelan, Patrick J

“…The hypothalamic A11 region has been identified in several species including rats, mice, cats, monkeys, zebrafish, and humans as the primary source of…”
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Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents by Burma, Nicole E, Bonin, Robert P, Leduc-Pessah, Heather, Baimel, Corey, Cairncross, Zoe F, Mousseau, Michael, Shankara, Jhenkruthi Vijaya, Stemkowski, Patrick L, Baimoukhametova, Dinara, Bains, Jaideep S, Antle, Michael C, Zamponi, Gerald W, Cahill, Catherine M, Borgland, Stephanie L, De Koninck, Yves, Trang, Tuan

“…The release of ATP from spinal microglia via pannexin-1 channels is required for withdrawal symptoms after termination of chronic opioid treatment in rodents,…”
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A genetically encoded fluorescent biosensor for extracellular l-lactate by Nasu, Yusuke, Murphy-Royal, Ciaran, Wen, Yurong, Haidey, Jordan N., Molina, Rosana S., Aggarwal, Abhi, Zhang, Shuce, Kamijo, Yuki, Paquet, Marie-Eve, Podgorski, Kaspar, Drobizhev, Mikhail, Bains, Jaideep S., Lemieux, M. Joanne, Gordon, Grant R., Campbell, Robert E.

“…l -Lactate, traditionally considered a metabolic waste product, is increasingly recognized as an important intercellular energy currency in mammals. To enable…”
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Presynaptic mGluRs Control the Duration of Endocannabinoid-Mediated DSI by Colmers, Phillip L W, Bains, Jaideep S

“…GABA synapses in the brain undergo depolarization-induced suppression of inhibition (DSI) that requires activation of presynaptic cannabinoid type 1 receptors…”
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MicroSweat: A Wearable Microfluidic Patch for Noninvasive and Reliable Sweat Collection Enables Human Stress Monitoring by Shajari, Shaghayegh, Salahandish, Razieh, Zare, Azam, Hassani, Mohsen, Moossavi, Shirin, Munro, Emily, Rashid, Ruba, Rosenegger, David, Bains, Jaideep S., Sanati Nezhad, Amir

“…Stress affects cognition, behavior, and physiology, leading to lasting physical and mental illness. The ability to detect and measure stress, however, is poor…”
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Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output by Hill, Matthew N, Patel, Sachin, Campolongo, Patrizia, Tasker, Jeffrey G, Wotjak, Carsten T, Bains, Jaideep S

“…Endocannabinoid signaling is distributed throughout the brain, regulating synaptic release of both excitatory and inhibitory neurotransmitters. The presence of…”
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Subcellular specificity of cannabinoid effects in striatonigral circuits by Soria-Gomez, Edgar, Pagano Zottola, Antonio C., Mariani, Yamuna, Desprez, Tifany, Barresi, Massimo, Bonilla-del Río, Itziar, Muguruza, Carolina, Le Bon-Jego, Morgane, Julio-Kalajzić, Francisca, Flynn, Robyn, Terral, Geoffrey, Fernández-Moncada, Ignacio, Robin, Laurie M., Oliveira da Cruz, José F., Corinti, Simone, Amer, Yasmine Ould, Goncalves, Julia, Varilh, Marjorie, Cannich, Astrid, Redon, Bastien, Zhao, Zhe, Lesté-Lasserre, Thierry, Vincent, Peggy, Tolentino-Cortes, Tarson, Busquets-García, Arnau, Puente, Nagore, Bains, Jaideep S., Hebert-Chatelain, Etienne, Barreda-Gómez, Gabriel, Chaouloff, Francis, Lohman, Alexander W., Callado, Luis F., Grandes, Pedro, Baufreton, Jerome, Marsicano, Giovanni, Bellocchio, Luigi

“…Recent advances in neuroscience have positioned brain circuits as key units in controlling behavior, implying that their positive or negative modulation…”
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Neurotransmitter diversity in pre‐synaptic terminals located in the parvicellular neuroendocrine paraventricular nucleus of the rat and mouse hypothalamus by Johnson, Caroline S., Bains, Jaideep S., Watts, Alan G.

“…Virtually all rodent neuroendocrine corticotropin‐releasing‐hormone (CRH) neurons are in the dorsal medial parvicellular (mpd) part of the paraventricular…”
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Olfactory bulb astrocytes link social transmission of stress to cognitive adaptation in male mice by Gómez-Sotres, Paula, Skupio, Urszula, Dalla Tor, Tommaso, Julio-Kalajzic, Francisca, Cannich, Astrid, Gisquet, Doriane, Bonilla-Del Rio, Itziar, Drago, Filippo, Puente, Nagore, Grandes, Pedro, Bellocchio, Luigi, Busquets-Garcia, Arnau, Bains, Jaideep S., Marsicano, Giovanni

“…Emotions and behavior can be affected by social chemosignals from conspecifics. For instance, olfactory signals from stressed individuals induce stress-like…”
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Hypothalamic CRH neurons represent physiological memory of positive and negative experience by Füzesi, Tamás, Rasiah, Neilen P., Rosenegger, David G., Rojas-Carvajal, Mijail, Chomiak, Taylor, Daviu, Núria, Molina, Leonardo A., Simone, Kathryn, Sterley, Toni-Lee, Nicola, Wilten, Bains, Jaideep S.

“…Recalling a salient experience provokes specific behaviors and changes in the physiology or internal state. Relatively little is known about how physiological…”
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Repeated stress impairs endocannabinoid signaling in the paraventricular nucleus of the hypothalamus by Wamsteeker, Jaclyn I, Kuzmiski, J Brent, Bains, Jaideep S

“…Endocannabinoids (eCBs) are ubiquitous retrograde signaling molecules in the nervous system that are recruited in response to robust neuronal activity or the…”
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Endocannabinoids Gate State-Dependent Plasticity of Synaptic Inhibition in Feeding Circuits by Crosby, Karen M., Inoue, Wataru, Pittman, Quentin J., Bains, Jaideep S.

“…Changes in food availability alter the output of hypothalamic nuclei that underlie energy homeostasis. Here, we asked whether food deprivation impacts the…”
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Asynchronous presynaptic glutamate release enhances neuronal excitability during the post‐spike refractory period by Iremonger, Karl J., Bains, Jaideep S.

“…Key Points Many excitatory synapses in the brain release glutamate with both synchronous and asynchronous components. Immediately following an action…”
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