Search Results - "Baine, Claire"

Persistent and robust antibody responses to ChAdOx1-S Oxford-AstraZeneca (ChAdOx1-S, Covishield) SARS-CoV-2 vaccine observed in Ugandans across varied baseline immune profiles by Serwanga, Jennifer, Oluka, Gerald Kevin, Baine, Claire, Ankunda, Violet, Sembera, Jackson, Kato, Laban, Katende, Joseph Ssebwana, Odoch, Geoffrey, Auma, Betty Oliver, Gombe, Ben, Musenero, Monica, Kaleebu, Pontiano

“…Understanding SARS-CoV-2 vaccine-induced antibody responses in varied antigenic and serological prior exposures can guide optimal vaccination strategies for…”
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Sustained spike-specific IgG antibodies following CoronaVac (Sinovac) vaccination in sub-Saharan Africa, but increased breakthrough infections in baseline spike-naive individuals by Sembera, Jackson, Baine, Claire, Ankunda, Violet, Katende, Joseph Ssebwana, Oluka, Gerald Kevin, Akoli, Christine Hermilia, Kato, Laban, Odoch, Geoffrey, Ejou, Peter, Opio, Solomon, Musenero, Monica, Kaleebu, Pontiano, Serwanga, Jennifer

“…This study investigated the antibody responses to the inactivated COVID-19 vaccine, CoronaVac (Sinovac Biotech) in the African population to provide valuable…”
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The single-dose Janssen Ad26.COV2.S COVID-19 vaccine elicited robust and persistent anti-spike IgG antibody responses in a 12-month Ugandan cohort by Serwanga, Jennifer, Kato, Laban, Oluka, Gerald Kevin, Ankunda, Violet, Sembera, Jackson, Baine, Claire, Kitabye, Isaac, Namuyanja, Angela, Opio, Solomon, Katende, Joseph Ssebwana, Ejou, Peter, Kaleebu, Pontiano

“…The study investigation examined the immune response to the Janssen Ad26.COV2.S COVID-19 vaccine within a Ugandan cohort, specifically targeting antibodies…”
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The subdued post-boost spike-directed secondary IgG antibody response in Ugandan recipients of the Pfizer-BioNTech BNT162b2 vaccine has implications for local vaccination policies by Ankunda, Violet, Katende, Joseph Ssebwana, Oluka, Gerald Kevin, Sembera, Jackson, Baine, Claire, Odoch, Geoffrey, Ejou, Peter, Kato, Laban, Kaleebu, Pontiano, Serwanga, Jennifer

“…This study aimed to delineate longitudinal antibody responses to the Pfizer-BioNTech BNT162b2 COVID-19 vaccine within the Ugandan subset of the Sub-Saharan…”
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Rapid, early, and potent Spike-directed IgG, IgM, and IgA distinguish asymptomatic from mildly symptomatic COVID-19 in Uganda, with IgG persisting for 28 months by Serwanga, Jennifer, Ankunda, Violet, Sembera, Jackson, Kato, Laban, Oluka, Gerald Kevin, Baine, Claire, Odoch, Geoffrey, Kayiwa, John, Auma, Betty Oliver, Jjuuko, Mark, Nsereko, Christopher, Cotten, Matthew, Onyachi, Nathan, Muwanga, Moses, Lutalo, Tom, Fox, Julie, Musenero, Monica, Kaleebu, Pontiano

“…Understanding how spike (S)-, nucleoprotein (N)-, and RBD-directed antibody responses evolved in mild and asymptomatic COVID-19 in Africa and their…”
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Sustained S-IgG and S-IgA antibodies to Moderna's mRNA-1273 vaccine in a Sub-Saharan African cohort suggests need for booster timing reconsiderations by Serwanga, Jennifer, Ankunda, Violet, Katende, Joseph Ssebwana, Baine, Claire, Oluka, Gerald Kevin, Odoch, Geoffrey, Nantambi, Hellen, Mugaba, Susan, Namuyanja, Angella, Ssali, Ivan, Ejou, Peter, Kato, Laban, Musenero, Monica, Kaleebu, Pontiano

“…This study sought to elucidate the long-term antibody responses to the Moderna mRNA-1273 COVID-19 vaccine within a Ugandan cohort, aiming to contribute to the…”
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Spike protein is a key target for stronger and more persistent T-cell responses—a study of mild and asymptomatic SARS-CoV-2 infection by Ssali, Ivan, Mugaba, Susan, Watelo, Arthur Kalyebi, Bemanzi, Juliana, Katende, Joseph Ssebwana, Oluka, Gerald Kevin, Ankunda, Violet, Baine, Claire, Kato, Laban, Onyachi, Nathan, Muwanga, Moses, Jjuuko, Mark, Kayiwa, John, Nsereko, Christopher, Auma, Betty Oliver, Weiskopf, Daniela, Sette, Alessandro, Lutalo, Tom, Musenero, Monica, Kaleebu, Pontiano, Serwanga, Jennifer

“…•Spike-induced interferon (IFN)-γ dominates in mild and asymptomatic COVID-19.•Primary infection anti-spike clusters of differentiation (CD4) IFN-γ persists…”
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Seroprevalence and durability of antibody responses to AstraZeneca vaccination in Ugandans with prior mild or asymptomatic COVID-19: implications for vaccine policy by Serwanga, Jennifer, Baine, Claire, Mugaba, Susan, Ankunda, Violet, Auma, Betty Oliver, Oluka, Gerald Kevin, Kato, Laban, Kitabye, Isaac, Sembera, Jackson, Odoch, Geoffrey, Ejou, Peter, Nalumansi, Amina, Gombe, Ben, Musenero, Monica, Kaleebu, Pontiano

“…The duration and timing of immunity conferred by COVID-19 vaccination in sub-Saharan Africa are crucial for guiding pandemic policy interventions, but…”
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An Optimised Indirect ELISA Protocol for Detection and Quantification of Anti-viral Antibodies in Human Plasma or Serum: A Case Study Using SARS-CoV-2 by Baine, Claire, Sembera, Jackson, Kevin Oluka, Gerald, Katende, Joseph Ssebwana, Ankunda, Violet, Serwanga, Jennifer

“…Advanced immunoassays are crucial in assessing antibody responses, serving immune surveillance goals, characterising immunological responses to evolving viral…”
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Pre-pandemic SARS-CoV-2-specific IFN-γ and antibody responses were low in Ugandan samples and significantly reduced in HIV-positive specimens by Nantambi, Hellen, Sembera, Jackson, Ankunda, Violet, Ssali, Ivan, Kalyebi, Arthur Watelo, Oluka, Gerald Kevin, Kato, Laban, Ubaldo, Bahemuka, Kibengo, Freddie, Katende, Joseph Ssebwana, Gombe, Ben, Baine, Claire, Odoch, Geoffrey, Mugaba, Susan, Sande, Obondo James, Kaleebu, Pontiano, Serwanga, Jennifer

“…We investigated whether prior SARS-CoV-2-specific IFN-γ and antibody responses in Ugandan COVID-19 pre-pandemic specimens aligned to this population's low…”
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Persistent and robust antibody responses to ChAdOx1-S Oxford-AstraZeneca by Serwanga, Jennifer, Oluka, Gerald Kevin, Baine, Claire, Ankunda, Violet, Sembera, Jackson, Kato, Laban, Katende, Joseph Ssebwana, Odoch, Geoffrey, Auma, Betty Oliver, Gombe, Ben, Musenero, Monica, Kaleebu, Pontiano

“…Understanding SARS-CoV-2 vaccine-induced antibody responses in varied antigenic and serological prior exposures can guide optimal vaccination strategies for…”
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Optimisation and Validation of a conventional ELISA and cut-offs for detecting and quantifying anti-SARS-CoV-2 Spike, RBD, and Nucleoprotein IgG, IgM, and IgA antibodies in Uganda by Oluka, Gerald Kevin, Namubiru, Patricia, Kato, Laban, Ankunda, Violet, Gombe, Ben, Cotten, Matthew, Musenero, Monica, Kaleebu, Pontiano, Fox, Julie, Serwanga, Jennifer

“…There is an urgent need for better immunoassays to measure antibody responses as part of immune-surveillance activities and to profile immunological responses…”
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