Search Results - "Bailin, Samuel"

The many landscapes of recombination in Drosophila melanogaster by Comeron, Josep M, Ratnappan, Ramesh, Bailin, Samuel

“…Recombination is a fundamental biological process with profound evolutionary implications. Theory predicts that recombination increases the effectiveness of…”
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Obesity and Weight Gain in Persons with HIV by Bailin, Samuel S., Gabriel, Curtis L., Wanjalla, Celestine N., Koethe, John R.

“…Purpose of Review The proportion of overweight and obese persons with HIV (PWH) has increased since the introduction of antiretroviral therapy (ART). We aim to…”
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Weight Gain and Antiretroviral Therapy by Bailin, Samuel S., Koethe, John R.

“…Antiretroviral therapy (ART) agents as a determinant of body weight in ART-naïve and ART-experienced persons with human immunodeficiency virus (HIV) (PWH) has…”
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Diabetes in HIV: the Link to Weight Gain by Bailin, Samuel S., Koethe, John R.

“…Purpose of Review The burden of metabolic diseases, including type 2 diabetes mellitus (T2DM), is rising among persons with HIV (PWH) on antiretroviral therapy…”
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Update on fungal infections of the central nervous system: emerging pathogens and emerging diagnostics by Bloch, Karen C, Bailin, Samuel S

“…PURPOSE OF REVIEWFungal infections of the central nervous system (CNS) are relatively uncommon but associated with significant morbidity and mortality. We…”
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The pathogenesis of obesity in people living with HIV by Bailin, Samuel S, Koethe, John R, Rebeiro, Peter F

“…The public health challenge of overweight and obesity increasingly affects people living with HIV (PWH). These effects have also accelerated as the prevalence…”
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Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis by Gibson, Andrew, Ram, Ramesh, Gangula, Rama, Li, Yueran, Mukherjee, Eric, Palubinsky, Amy M., Campbell, Chelsea N., Thorne, Michael, Konvinse, Katherine C., Choshi, Phuti, Deshpande, Pooja, Pedretti, Sarah, Fear, Mark W., Wood, Fiona M., O’Neil, Richard T., Wanjalla, Celestine N., Kalams, Spyros A., Gaudieri, Silvana, Lehloenya, Rannakoe J., Bailin, Samuel S., Chopra, Abha, Trubiano, Jason A., Peter, Jonny G., Mallal, Simon A., Phillips, Elizabeth J.

“…Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen…”
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Circulating CD4+ TEMRA and CD4+ CD28− T cells and incident diabetes among persons with and without HIV by Bailin, Samuel S., Kundu, Suman, Wellons, Melissa, Freiberg, Matthew S., Doyle, Margaret F., Tracy, Russell P., Justice, Amy C., Wanjalla, Celestine N., Landay, Alan L., So-Armah, Kaku, Mallal, Simon, Kropski, Jonathan A., Koethe, John R.

“…A higher proportion of circulating memory CD4+ T cells is associated with prevalent diabetes mellitus in persons with HIV (PWH) and HIV-negative persons. We…”
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Cytokine and chemokine receptor profiles in adipose tissue vasculature unravel endothelial cell responses in HIV by Obare, Laventa M., Priest, Stephen, Ismail, Anas, Mashayekhi, Mona, Zhang, Xiuqi, Stolze, Lindsey K., Sheng, Quanhu, Nthenge, Kisyua, Vue, Zer, Neikirk, Kit, Beasley, Heather K., Gabriel, Curtis, Temu, Tecla, Gianella, Sara, Mallal, Simon A., Koethe, John R., Hinton, Antentor, Bailin, Samuel S., Wanjalla, Celestine N.

“…Chronic systemic inflammation significantly increases myocardial infarction risk in people living with HIV (PLWH). Endothelial cell dysfunction disrupts…”
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Single-Cell Analysis of Subcutaneous Fat Reveals Profibrotic Cells That Correlate With Visceral Adiposity in HIV by Bailin, Samuel S, Gabriel, Curtis L, Gangula, Rama D, Hannah, LaToya, Nair, Sangeeta, Carr, John Jeffrey, Terry, James G, Silver, Heidi J, Simmons, Joshua D, Mashayekhi, Mona, Kalams, Spyros A, Mallal, Simon, Kropski, Jonathan A, Wanjalla, Celestine N, Koethe, John R

“…Abstract Context Cardiometabolic diseases are common in persons with HIV (PWH) on antiretroviral therapy (ART), which has been attributed to preferential lipid…”
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Changes in subcutaneous white adipose tissue cellular composition and molecular programs underlie glucose intolerance in persons with HIV by Bailin, Samuel S, Kropski, Jonathan A, Gangula, Rama D, Hannah, LaToya, Simmons, Joshua D, Mashayekhi, Mona, Ye, Fei, Fan, Run, Mallal, Simon, Warren, Christian M, Kalams, Spyros A, Gabriel, Curtis L, Wanjalla, Celestine N, Koethe, John R

“…Subcutaneous adipose tissue (SAT) is a critical regulator of systemic metabolic homeostasis. Persons with HIV (PWH) have an increased risk of metabolic…”
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T Lymphocyte Subsets Associated With Prevalent Diabetes in Veterans With and Without Human Immunodeficiency Virus by Bailin, Samuel S, McGinnis, Kathleen A, McDonnell, Wyatt J, So-Armah, Kaku, Wellons, Melissa, Tracy, Russell P, Doyle, Margaret F, Mallal, Simon, Justice, Amy C, Freiberg, Matthew S, Landay, Alan L, Wanjalla, Celestine, Koethe, John R

“…Abstract Background A higher proportion of circulating memory CD4+ T cells is associated with prevalent diabetes mellitus in the general population. Given the…”
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Mean Coronary Cross-Sectional Area as a Measure of Arterial Remodeling Using Noncontrast CT Imaging in Persons With HIV by Werede, Ayoda T, Terry, James G, Nair, Sangeeta, Temu, Tecla M, Shepherd, Bryan E, Bailin, Samuel S, Mashayekhi, Mona, Gabriel, Curtis L, Lima, Morgan, Woodward, Beverly Owen, Hannah, LaToya, Mallal, Simon A, Beckman, Joshua A, Li, Jonathan Z, Fajnzylber, Jesse, Harrison, David G, Carr, John Jeffrey, Koethe, John R, Wanjalla, Celestine N

“…Background Persons with HIV have a higher prevalence of coronary artery disease compared with their HIV-negative counterparts. Earlier identification of…”
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Relationship of Subcutaneous Adipose Tissue Inflammation–Related Gene Expression With Ectopic Lipid Deposition in Persons With HIV by Bailin, Samuel S., Gabriel, Curtis L., Fan, Run, Ye, Fei, Nair, Sangeeta, Terry, James G., Carr, John J., Silver, Heidi, Wanjalla, Celestine N., Mashayekhi, Mona, Lima, Morgan, Woodward, Beverly, Hannah, LaToya, Fuseini, Hubaida, Ferguson, Jane F., Kropski, Jonathan A., Koethe, John R.

“…Fat redistribution from subcutaneous adipose tissue (SAT) to the abdominal viscera, pericardium, liver, and skeletal muscle contributes to the rising burden of…”
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CD4 + T cells expressing CX3CR1, GPR56, with variable CD57 are associated with cardiometabolic diseases in persons with HIV by Wanjalla, Celestine N, Gabriel, Curtis L, Fuseini, Hubaida, Bailin, Samuel S, Mashayekhi, Mona, Simmons, Joshua, Warren, Christopher M, Glass, David R, Oakes, Jared, Gangula, Rama, Wilfong, Erin, Priest, Stephen, Temu, Tecla, Newell, Evan W, Pakala, Suman, Kalams, Spyros A, Gianella, Sara, Smith, David, Harrison, David G, Mallal, Simon A, Koethe, John R

“…Persons with HIV (PWH) on long-term antiretroviral therapy (ART) have a higher incidence and prevalence of cardiometabolic diseases attributed, in part, to…”
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The subcutaneous adipose transcriptome identifies a molecular signature of insulin resistance shared with visceral adipose by Mashayekhi, Mona, Sheng, Quanhu, Bailin, Samuel S., Massier, Lucas, Zhong, Jiawei, Shi, Mingjian, Wanjalla, Celestine N., Wang, Thomas J., Ikizler, T. Alp, Niswender, Kevin D., Gabriel, Curtis L., Palacios, Julia, Turgeon‐Jones, Rachel, Reynolds, Cassandra F., Luther, James M., Brown, Nancy J., Das, Saumya, Dahlman, Ingrid, Mosley, Jonathan D., Koethe, John R., Rydén, Mikael, Bachmann, Katherine N., Shah, Ravi V.

“…Objective The objective of this study was to identify the transcriptional landscape of insulin resistance (IR) in subcutaneous adipose tissue (SAT) in humans…”
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Leptin Promotes Greater Ki67 Expression in CD4 + T Cells From Obese Compared to Lean Persons Living With HIV by Fuseini, Hubaida, Smith, Rita, Nochowicz, Cindy H, Simmons, Joshua D, Hannah, LaToya, Wanjalla, Celestine N, Gabriel, Curtis L, Mashayekhi, Mona, Bailin, Samuel S, Castilho, Jessica L, Hasty, Alyssa H, Koethe, John R, Kalams, Spyros A

“…While antiretroviral therapy (ART) has proven effective in suppressing viremia and disease progression among people living with human immunodeficiency virus…”
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The soluble epoxide hydrolase inhibitor GSK2256294 decreases the proportion of adipose pro-inflammatory T cells by Mashayekhi, Mona, Wanjalla, Celestine N., Warren, Christian M., Simmons, Joshua D., Ghoshal, Kakali, Pilkinton, Mark, Bailin, Samuel S., Gabriel, Curtis L., Pozzi, Ambra, Koethe, John R., Brown, Nancy J., Kalams, Spyros A., Luther, J. Matthew

“…•sEH inhibition decreases adipose tissue IFNγ-producing T helper cells and secreted TNFα.•sEH inhibition does not affect adipose tissue IL-17A…”
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Lower Concentrations of Circulating Medium and Long-Chain Acylcarnitines Characterize Insulin Resistance in Persons with HIV by Bailin, Samuel S, Jenkins, Cathy A, Petucci, Christopher, Culver, Jeffrey A, Shepherd, Bryan E, Fessel, Joshua P, Hulgan, Todd, Koethe, John R

“…In human immunodeficiency virus (HIV)-negative individuals, a plasma metabolite profile, characterized by higher levels of branched-chain amino acids (BCAA),…”
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Toxoplasmosis: The Heart of the Diagnosis by England, James H, Bailin, Samuel S, Gehlhausen, Jeffrey R, Rubin, Donald H

“…Abstract Toxoplasma gondii is a common parasite that infects warm-blooded animals, including humans, and is a foodborne pathogen. We report a case of acute…”
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