Search Results - "Bailey, Timothy"

STREME: accurate and versatile sequence motif discovery by Bailey, Timothy L

“…Sequence motif discovery algorithms can identify novel sequence patterns that perform biological functions in DNA, RNA and protein sequences-for example, the…”
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DREME: motif discovery in transcription factor ChIP-seq data by BAILEY, Timothy L

“…Transcription factor (TF) ChIP-seq datasets have particular characteristics that provide unique challenges and opportunities for motif discovery. Most existing…”
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Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data by McLeay, Robert C, Bailey, Timothy L

“…A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine…”
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MEME-ChIP: motif analysis of large DNA datasets by MACHANICK, Philip, BAILEY, Timothy L

“…Advances in high-throughput sequencing have resulted in rapid growth in large, high-quality datasets including those arising from transcription factor (TF)…”
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Defining the RGG/RG Motif by Thandapani, Palaniraja, O’Connor, Timothy R., Bailey, Timothy L., Richard, Stéphane

“…Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or…”
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Inferring direct DNA binding from ChIP-seq by Bailey, Timothy L, Machanick, Philip

“…Genome-wide binding data from transcription factor ChIP-seq experiments is the best source of information for inferring the relative DNA-binding affinity of…”
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Statistical confidence estimation for Hi-C data reveals regulatory chromatin contacts by Ay, Ferhat, Bailey, Timothy L, Noble, William Stafford

“…Our current understanding of how DNA is packed in the nucleus is most accurate at the fine scale of individual nucleosomes and at the large scale of chromosome…”
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The MEME Suite by Bailey, Timothy L, Johnson, James, Grant, Charles E, Noble, William S

“…The MEME Suite is a powerful, integrated set of web-based tools for studying sequence motifs in proteins, DNA and RNA. Such motifs encode many biological…”
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FIMO: scanning for occurrences of a given motif by GRANT, Charles E, BAILEY, Timothy L, STAFFORD NOBLE, William

“…A motif is a short DNA or protein sequence that contributes to the biological function of the sequence in which it resides. Over the past several decades, many…”
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Switching on sex: transcriptional regulation of the testis-determining gene Sry by Larney, Christian, Bailey, Timothy L, Koopman, Peter

“…Mammalian sex determination hinges on the development of ovaries or testes, with testis fate being triggered by the expression of the transcription factor…”
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Options for Combination Therapy in Type 2 Diabetes: Comparison of the ADA/EASD Position Statement and AACE/ACE Algorithm by Bailey, Timothy, MD

“…Abstract Treating patients with diabetes is one of the most challenging and important activities a physician (primary care physician or specialist) can…”
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MoMo: discovery of statistically significant post-translational modification motifs by Cheng, Alice, Grant, Charles E, Noble, William S, Bailey, Timothy L

“…Post-translational modifications (PTMs) of proteins are associated with many significant biological functions and can be identified in high throughput using…”
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GT-Scan: identifying unique genomic targets by O'Brien, Aidan, Bailey, Timothy L

“…A number of technologies, including CRISPR/Cas, transcription activator-like effector nucleases and zinc-finger nucleases, allow the user to target a chosen…”
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Clinical Accuracy of a Continuous Glucose Monitoring System With an Advanced Algorithm by Bailey, Timothy S., Chang, Anna, Christiansen, Mark

“…Background: We assessed the performance of a modified Dexcom G4 Platinum system with an advanced algorithm, in comparison with frequent venous samples measured…”
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Landscape of Continuous Glucose Monitoring (CGM) and Integrated CGM: Accuracy Considerations by Bailey, Timothy S, Alva, Shridhara

“…Continuous glucose monitoring devices have significantly improved in many respects compared with earlier versions. As sensor accuracy improved, U.S. Food and…”
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Clinical Implications of Accuracy Measurements of Continuous Glucose Sensors by Bailey, Timothy S

“…The accuracy of a continuous glucose monitor (CGM) now supports its use by persons with diabetes and clinicians caring for them. This article reviews measures…”
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Quantifying similarity between motifs by Gupta, Shobhit, Stamatoyannopoulos, John A, Bailey, Timothy L, Noble, William Stafford

“…A common question within the context of de novo motif discovery is whether a newly discovered, putative motif resembles any previously discovered motif in an…”
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Motif-based analysis of large nucleotide data sets using MEME-ChIP by Ma, Wenxiu, Noble, William S, Bailey, Timothy L

“…This protocol enables users to perform de novo motif discovery, motif enrichment analysis, motif location analysis, and motif clustering, providing a…”
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Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity: The STEP 3 Randomized Clinical Trial by Wadden, Thomas A, Bailey, Timothy S, Billings, Liana K, Davies, Melanie, Frias, Juan P, Koroleva, Anna, Lingvay, Ildiko, O’Neil, Patrick M, Rubino, Domenica M, Skovgaard, Dorthe, Wallenstein, Signe O. R, Garvey, W. Timothy

“…IMPORTANCE: Weight loss improves cardiometabolic risk factors in people with overweight or obesity. Intensive lifestyle intervention and pharmacotherapy are…”
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The Performance and Usability of a Factory-Calibrated Flash Glucose Monitoring System by Bailey, Timothy, Bode, Bruce W, Christiansen, Mark P, Klaff, Leslie J, Alva, Shridhara

“…The purpose of the study was to evaluate the performance and usability of the FreeStyle(®) Libre™ Flash glucose monitoring system (Abbott Diabetes Care,…”
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