Search Results - "Bailey, T. A."

Reconstructing aspects of human embryogenesis with pluripotent stem cells by Sozen, Berna, Jorgensen, Victoria, Weatherbee, Bailey A. T., Chen, Sisi, Zhu, Meng, Zernicka-Goetz, Magdalena

“…Understanding human development is of fundamental biological and clinical importance. Despite its significance, mechanisms behind human embryogenesis remain…”
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Developmental potential of aneuploid human embryos cultured beyond implantation by Shahbazi, Marta N., Wang, Tianren, Tao, Xin, Weatherbee, Bailey A. T., Sun, Li, Zhan, Yiping, Keller, Laura, Smith, Gary D., Pellicer, Antonio, Scott, Richard T., Seli, Emre, Zernicka-Goetz, Magdalena

“…Aneuploidy, the presence of an abnormal number of chromosomes, is a major cause of early pregnancy loss in humans. Yet, the developmental consequences of…”
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A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre by Molè, Matteo A., Coorens, Tim H. H., Shahbazi, Marta N., Weberling, Antonia, Weatherbee, Bailey A. T., Gantner, Carlos W., Sancho-Serra, Carmen, Richardson, Lucy, Drinkwater, Abbie, Syed, Najma, Engley, Stephanie, Snell, Philip, Christie, Leila, Elder, Kay, Campbell, Alison, Fishel, Simon, Behjati, Sam, Vento-Tormo, Roser, Zernicka-Goetz, Magdalena

“…Following implantation, the human embryo undergoes major morphogenetic transformations that establish the future body plan. While the molecular events…”
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Expression of SARS-CoV-2 receptor ACE2 and the protease TMPRSS2 suggests susceptibility of the human embryo in the first trimester by Weatherbee, Bailey A T, Glover, David M, Zernicka-Goetz, Magdalena

“…While initially recognized as causing respiratory disease, the SARS-CoV-2 virus also affects many other organs leading to other complications. It has emerged…”
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The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development by Aryal, Sandeep, Viet, Justine, Weatherbee, Bailey A. T., Siddam, Archana D., Hernandez, Francisco G., Gautier-Courteille, Carole, Paillard, Luc, Lachke, Salil A.

“…The homeodomain transcription factors (TFs) Pax6 (OMIM: 607108) and Prox1 (OMIM: 601546) critically regulate gene expression in lens development. While PAX6…”
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Distinct pathways drive anterior hypoblast specification in the implanting human embryo by Weatherbee, Bailey A. T., Weberling, Antonia, Gantner, Carlos W., Iwamoto-Stohl, Lisa K., Barnikel, Zoe, Barrie, Amy, Campbell, Alison, Cunningham, Paula, Drezet, Cath, Efstathiou, Panagiota, Fishel, Simon, Vindel, Sandra Gutiérrez, Lockwood, Megan, Oakley, Rebecca, Pretty, Catherine, Chowdhury, Nabiha, Richardson, Lucy, Mania, Anastasia, Weavers, Lauren, Christie, Leila, Elder, Kay, Snell, Phillip, Zernicka-Goetz, Magdalena

“…Development requires coordinated interactions between the epiblast, which generates the embryo proper; the trophectoderm, which generates the placenta; and the…”
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MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract by Aryal, Sandeep, Anand, Deepti, Hernandez, Francisco G., Weatherbee, Bailey A. T., Huang, Hongzhan, Reddy, Ashok P., Wilmarth, Phillip A., David, Larry L., Lachke, Salil A.

“…While the bioinformatics resource-tool iSyTE (integrated Systems Tool for Eye gene discovery) effectively identifies human cataract-associated genes, it is…”
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High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology by Siddam, Archana D, Duot, Matthieu, Coomson, Sarah Y, Anand, Deepti, Aryal, Sandeep, Weatherbee, Bailey A T, Audic, Yann, Paillard, Luc, Lachke, Salil A

“…Defects in the development of the ocular lens can cause congenital cataracts. To understand the various etiologies of congenital cataracts, it is important to…”
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Pluripotent stem cell-derived model of the post-implantation human embryo by Weatherbee, Bailey A. T., Gantner, Carlos W., Iwamoto-Stohl, Lisa K., Daza, Riza M., Hamazaki, Nobuhiko, Shendure, Jay, Zernicka-Goetz, Magdalena

“…The human embryo undergoes morphogenetic transformations following implantation into the uterus, but our knowledge of this crucial stage is limited by the…”
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Modeling human embryo development with embryonic and extra-embryonic stem cells by Weatherbee, Bailey A.T., Cui, Tongtong, Zernicka-Goetz, Magdalena

“…Early human post-implantation development involves extensive growth combined with a series of complex morphogenetic events. The lack of precise spatial and…”
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An in vitro stem cell model of human epiblast and yolk sac interaction by Mackinlay, Kirsty Ml, Weatherbee, Bailey At, Souza Rosa, Viviane, Handford, Charlotte E, Hudson, George, Coorens, Tim, Pereira, Lygia V, Behjati, Sam, Vallier, Ludovic, Shahbazi, Marta N, Zernicka-Goetz, Magdalena

“…Human embryogenesis entails complex signalling interactions between embryonic and extra-embryonic cells. However, how extra-embryonic cells direct…”
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Assembly of a stem cell-derived human postimplantation embryo model by Gantner, Carlos W, Weatherbee, Bailey A T, Wang, Yuntao, Zernicka-Goetz, Magdalena

“…The embryonic and extraembryonic tissue interactions underlying human embryogenesis at implantation stages are not currently understood. We have generated a…”
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Susceptibility of fungi isolated from the respiratory tract of falcons to amphotericin B, itraconazole and voriconazole by Silvanose, C. D., Bailey, T. A., Di Somma, A.

“…The minimum inhibitory concentrations (mics) of fungi isolated from the air sacs of falcons before (group 1), and during antifungal treatment with amphotericin…”
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Publisher Correction: Pluripotent stem cell-derived model of the post-implantation human embryo by Weatherbee, Bailey A. T., Gantner, Carlos W., Iwamoto-Stohl, Lisa K., Daza, Riza M., Hamazaki, Nobuhiko, Shendure, Jay, Zernicka-Goetz, Magdalena

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Molecular characterization of the human lens epithelium-derived cell line SRA01/04 by Weatherbee, Bailey A.T., Barton, Joshua R., Siddam, Archana D., Anand, Deepti, Lachke, Salil A.

“…Cataract-associated gene discovery in human and animal models have informed on key aspects of human lens development, homeostasis and pathology. Additionally,…”
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Enhancement of tritium concentrations on uptake by marine biota: experience from UK coastal waters by Hunt, G J, Bailey, T A, Jenkinson, S B, Leonard, K S

“…Concentrations of tritium in sea water and marine biota as reported over the last approximately 10 years from monitoring programmes carried out by this…”
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Assessment of a commercial sandwich ELISA in the diagnosis of aspergillosis in falcons by Arca-Ruibal, B., Wernery, U., Zachariah, R., Bailey, T. A., Di Somma, A., Silvanose, C., McKinney, P.

“…A commercial sandwich ELISA (Platelia Aspergillus EIA; Bio-Rad) developed for the detection of galactomannan, a major cell wall constituent of Aspergillus…”
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Understanding and treating depression among cancer patients by Bailey, R K, Geyen, D J, Scott-Gurnell, K, Hipolito, M M S, Bailey, T A, Beal, J M

“…Cancer is a devastating disease. Awareness of this disorder tremendously impacts an individual's life, creating a host of changes to occur. Depression is one…”
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Matrix metalloproteinase biology applied to vitreoretinal disorders by SETHI, C S, BAILEY, T A, LUTHERT, P J, CHONG, N H V

“…[...]while we continue to tackle established vitreoretinal pathologies in the new millennium, matrix biology will be contributing significantly to our…”
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Acute phase proteins in three healthy antelope species by Baldrey, V., Verghese, R., Wernery, U., Bailey, T. A.

“…Sodium citrate was used as an anticoagulant in the samples collected for fibrinogen assay as fibrinogen is removed with the clot in serum separation resulting…”
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