Search Results - "Bailey, Sarah E R"
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Association between patient ethnicity and prostate cancer diagnosis following a prostate-specific antigen test: a cohort study of 730,000 men in primary care in the UK
Published in BMC medicine (01-03-2024)“…Black men have higher prostate-specific antigen (PSA) levels and higher prostate cancer incidence and mortality than White men, while Asian men tend to have…”
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The diagnostic performance of CA-125 for the detection of ovarian cancer in women from different ethnic groups: a cohort study of English primary care data
Published in Journal of ovarian research (26-08-2024)“…CA-125 testing is a recommended first line investigation for women presenting with possible symptoms of ovarian cancer in English primary care, to help…”
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Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank
Published in British journal of cancer (01-11-2022)“…Background Prostate cancer is highly heritable, with >250 common variants associated in genome-wide association studies. It commonly presents with non-specific…”
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The Clinical Value of Pre-Diagnostic Thrombocytosis for the Detection of Lung Cancer in Primary Care
Published in Cancers (14-03-2024)“…Thrombocytosis is a risk marker for lung cancer in primary care. We investigated whether thrombocytosis presents pre-diagnostically for all the histological…”
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Colorectal cancer risk stratification using a polygenic risk score in symptomatic primary care patients-a UK Biobank retrospective cohort study
Published in European journal of human genetics : EJHG (01-08-2024)“…Colorectal cancer (CRC) is a leading cause of cancer mortality worldwide. Accurate cancer risk assessment approaches could increase rates of early CRC…”
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How useful is thrombocytosis in predicting an underlying cancer in primary care? a systematic review
Published in Family practice (01-02-2017)“…Although the association between raised platelet count (thrombocytosis) and cancer has been reported in primary and secondary care studies, UK GPs are unaware…”
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Response to: Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis (BJC-LT3342090)
Published in British journal of cancer (16-02-2023)Get full text
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Exploring the Causes of Death Among Patients With Metastatic Prostate Cancer-A Changing Landscape
Published in JAMA network open (02-08-2021)Get full text
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Colorectal cancer in symptomatic patients: How to improve the diagnostic pathway
Published in Baillière's best practice & research. Clinical gastroenterology (01-10-2023)Get full text
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Diagnostic performance of a faecal immunochemical test for patients with low-risk symptoms of colorectal cancer in primary care: an evaluation in the South West of England
Published in British journal of cancer (30-03-2021)“…Background The faecal immunochemical test (FIT) was introduced to triage patients with low-risk symptoms of possible colorectal cancer in English primary care…”
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Cancer incidence in patients with a high normal platelet count: a cohort study using primary care data
Published in Family practice (12-12-2018)“…A platelet count >400 × 109/l (i.e. thrombocytosis) is a recently discovered risk marker of cancer. The risk of undiagnosed cancer in patients with…”
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Faecal immunochemical test to triage patients with abdominal symptoms for suspected colorectal cancer in primary care: review of international use and guidelines
Published in Family practice (19-10-2020)“…Recently, faecal immunochemical tests (FITs) have been introduced for investigation of primary care patients with low-risk symptoms of colorectal cancer (CRC),…”
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Improving the Clinical Utility of Platelet Count for Cancer Detection in Primary Care: A Cohort Study in England, Canada, and Australia
Published in Cancers (04-09-2024)“…The platelet count, a component of the full blood count, has been identified as a useful diagnostic marker for cancer in primary care. The reference range for…”
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Determining the role of genetic risk scores in symptomatic cancer detection
Published in British journal of general practice (01-03-2023)“…Improving cancer diagnosis is a national priority in the UK. with the NHS Long Term Plan pledging to increase the percentage of cancers found at an early stage…”
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The association between thrombocytosis and subtype of lung cancer: a systematic review and meta-analysis
Published in Translational cancer research (01-03-2021)“…Thrombocytosis is associated with poor lung cancer prognosis and has recently been identified as having a high positive predictive value in lung cancer…”
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Blood markers for cancer
Published in BMJ (Online) (14-10-2019)“…Cancer can be difficult to identify, as many of the common symptoms are non-specific and low risk, and even the most well known “alarm” symptoms have…”
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Clinical relevance of thrombocytosis in primary care: a prospective cohort study of cancer incidence using English electronic medical records and cancer registry data
Published in British journal of general practice (01-06-2017)“…Thrombocytosis (raised platelet count) is an emerging risk marker of cancer, but the association has not been fully explored in a primary care context. To…”
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Association of non-malignant diseases with thrombocytosis: a prospective cohort study in general practice
Published in British journal of general practice (01-12-2020)“…Thrombocytosis is an excess of platelets, which is diagnosed as a platelet count >400 × 10 /l. An association of thrombocytosis with undiagnosed cancer has…”
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Cancer incidence following a high-normal platelet count: cohort study using electronic healthcare records from English primary care
Published in British journal of general practice (01-09-2020)“…Background A raised platelet count (thrombocytosis) measuring >400 × 10 9 /l is associated with high cancer incidence. It is uncertain whether platelet counts…”
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Authors’ response
Published in British journal of general practice (01-09-2017)Get full text
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