Search Results - "Bailey, Jennifer M."

EMT and Dissemination Precede Pancreatic Tumor Formation by Rhim, Andrew D., Mirek, Emily T., Aiello, Nicole M., Maitra, Anirban, Bailey, Jennifer M., McAllister, Florencia, Reichert, Maximilian, Beatty, Gregory L., Rustgi, Anil K., Vonderheide, Robert H., Leach, Steven D., Stanger, Ben Z.

“…Metastasis is the leading cause of cancer-associated death but has been difficult to study because it involves a series of rare, stochastic events. To capture…”
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Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer by Zhang, Yu, Chandra, Vidhi, Riquelme Sanchez, Erick, Dutta, Prasanta, Quesada, Pompeyo R, Rakoski, Amanda, Zoltan, Michelle, Arora, Nivedita, Baydogan, Seyda, Horne, William, Burks, Jared, Xu, Hanwen, Hussain, Perwez, Wang, Huamin, Gupta, Sonal, Maitra, Anirban, Bailey, Jennifer M, Moghaddam, Seyed J, Banerjee, Sulagna, Sahin, Ismet, Bhattacharya, Pratip, McAllister, Florencia

“…Pancreatic ductal adenocarcinoma (PDAC) remains a lethal malignancy with an immunosuppressive microenvironment that is resistant to most therapies. IL17 is…”
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Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia by McAllister, Florencia, Bailey, Jennifer M., Alsina, Janivette, Nirschl, Christopher J., Sharma, Rajni, Fan, Hongni, Rattigan, Yanique, Roeser, Jeffrey C., Lankapalli, Rachana H., Zhang, Hao, Jaffee, Elizabeth M., Drake, Charles G., Housseau, Franck, Maitra, Anirban, Kolls, Jay K., Sears, Cynthia L., Pardoll, Drew M., Leach, Steven D.

“…Many human cancers are dramatically accelerated by chronic inflammation. However, the specific cellular and molecular elements mediating this effect remain…”
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Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions by Choi, Eunyoung, Hendley, Audrey M, Bailey, Jennifer M, Leach, Steven D, Goldenring, James R

“…Background & Aims Gastric cancer develops in the context of parietal cell loss, spasmolytic polypeptide-expressing metaplasia (SPEM), and intestinal metaplasia…”
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Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer by BAILEY, Jennifer M, SWANSON, Benjamin J, HAMADA, Tomofumi, EGGERS, John P, SINGH, Pankaj K, CAFFERY, Thomas, OUELLETTE, Michel M, HOLLINGSWORTH, Michael A

“…Purpose: We investigated the contribution of Sonic hedgehog (SHH) to pancreatic cancer progression. Experimental Design: We expressed SHH in a transformed…”
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Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins by Bailey, Jennifer M., Singh, Pankaj K., Hollingsworth, Michael A.

“…This review will highlight the significance of three critical pathways in developmental biology and our emerging understanding of their roles in regulating…”
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Radiofrequency ablation in combination with CD73 inhibitor AB680 reduces tumor growth and enhances anti-tumor immunity in a syngeneic model of pancreatic ductal adenocarcinoma by Faraoni, Erika Y, Strickland, Lincoln N, O'Brien, Baylee J, Barraza, Joseph F, Thosani, Nirav C, Wray, Curtis J, Mills, Tingting W, Bailey-Lundberg, Jennifer M

“…Pancreatic ductal adenocarcinoma presents a 5-year overall survival rate of 11%, placing an imperative need for the discovery and application of innovative…”
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Structure of the 5′ Nontranslated Region of the Coxsackievirus B3 Genome: Chemical Modification and Comparative Sequence Analysis by BAILEY, Jennifer M, TAPPRICH, William E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia by Hendley, Audrey M, Wang, Yue J, Polireddy, Kishore, Alsina, Janivette, Ahmed, Ishrat, Lafaro, Kelly J, Zhang, Hao, Roy, Nilotpal, Savidge, Samuel G, Cao, Yanna, Hebrok, Matthias, Maitra, Anirban, Reynolds, Albert B, Goggins, Michael, Younes, Mamoun, Iacobuzio-Donahue, Christine A, Leach, Steven D, Bailey, Jennifer M

“…Aberrant regulation of cellular extrusion can promote invasion and metastasis. Here, we identify molecular requirements for early cellular invasion using a…”
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Sphere-forming assays for assessment of benign and malignant pancreatic stem cells by Wang, Yue J, Bailey, Jennifer M, Rovira, Meritxell, Leach, Steven D

“…Sphere-forming assays are an in vitro technique to assay both normal and neoplastic cells for clonogenic growth potential. Currently, the identification of…”
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MUC1 regulates expression of multiple microRNAs involved in pancreatic tumor progression, including the miR-200c/141 cluster by Mohr, Ashley M, Bailey, Jennifer M, Lewallen, Michelle E, Liu, Xiang, Radhakrishnan, Prakash, Yu, Fang, Tapprich, William, Hollingsworth, Michael A

“…MUC1 is a transmembrane glycoprotein that modulates transcription via its cytoplasmic domain. We evaluated the capacity of MUC1 to regulate the global…”
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Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for advanced pancreatic and periampullary adenocarcinoma by Thosani, Nirav, Cen, Putao, Rowe, Julie, Guha, Sushovan, Bailey-Lundberg, Jennifer M., Bhakta, Dimpal, Patil, Prithvi, Wray, Curtis J.

“…Long term prognosis and 5-year survival for pancreatic adenocarcinoma (PDAC) remains suboptimal. Endoscopic ultrasound (EUS) guided RFA (EUS-RFA) is an…”
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Pancreatic stromal Gremlin 1 expression during pancreatic tumorigenesis by Davis, Joy M., Cheng, Binglu, Drake, Madeline M., Yu, Qiang, Yang, Baibing, Li, Jing, Liu, Chunhui, Younes, Mamoun, Zhao, Xiurong, Bailey, Jennifer M., Shen, Qiang, Ko, Tien C., Cao, Yanna

“…Chronic pancreatitis (CP) is a major risk factor of pancreatic ductal adenocarcinoma (PDAC). How CP promotes pancreatic oncogenesis remains unclear. A…”
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Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer by Singh, Kanchan, Pruski, Melissa, Bland, Rachael, Younes, Mamoun, Guha, Sushovan, Thosani, Nirav, Maitra, Anirban, Cash, Brooks D., McAllister, Florencia, Logsdon, Craig D., Chang, Jeffrey T., Bailey-Lundberg, Jennifer M.

“…Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States. Despite the high prevalence of Kras mutations…”
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Editorial: Emerging anti-cancer compounds and immunomodulators for pancreatic cancer treatment by DelGiorno, Kathleen E, Safe, Stephen, Bailey-Lundberg, Jennifer M

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Phosphorylation of MUC1 by Met Modulates Interaction with p53 and MMP1 Expression by Singh, Pankaj K., Behrens, Michelle E., Eggers, John P., Cerny, Ronald L., Bailey, Jennifer M., Shanmugam, Kandavel, Gendler, Sandra J., Bennett, Eric P., Hollingsworth, Michael A.

“…MUC1, a transmembrane mucin, is a key modulator of several signaling pathways that affect oncogenesis, motility, and cell morphology. The interaction of MUC1…”
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Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia by Wang, Yue J, McAllister, Florencia, Bailey, Jennifer M, Scott, Sherri-Gae, Hendley, Audrey M, Leach, Steven D, Ghosh, Bidyut

“…The role of miRNA processing in the maintenance of adult pancreatic acinar cell identity and during the initiation and progression of pancreatic neoplasia has…”
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PanIN Neuroendocrine Cells Promote Tumorigenesis via Neuronal Cross-talk by Sinha, Smrita, Fu, Ya-Yuan, Grimont, Adrien, Ketcham, Maren, Lafaro, Kelly, Saglimbeni, Joseph A, Askan, Gokce, Bailey, Jennifer M, Melchor, Jerry P, Zhong, Yi, Joo, Min Geol, Grbovic-Huezo, Olivera, Yang, In-Hong, Basturk, Olca, Baker, Lindsey, Park, Young, Kurtz, Robert C, Tuveson, David, Leach, Steven D, Pasricha, Pankaj J

“…Nerves are a notable feature of the tumor microenvironment in some epithelial tumors, but their role in the malignant progression of pancreatic ductal…”
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The TGF-β superfamily as potential therapeutic targets in pancreatic cancer by Tindall, Rachel R, Bailey-Lundberg, Jennifer M, Cao, Yanna, Ko, Tien C

“…The transforming growth factor (TGF)-β superfamily has important physiologic roles and is dysregulated in many pathologic processes, including pancreatic…”
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The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer by Strickland, Lincoln N, Faraoni, Erika Y, Ruan, Wei, Yuan, Xiaoyi, Eltzschig, Holger K, Bailey-Lundberg, Jennifer M

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by a dense desmoplastic stroma that impedes drug delivery, reduces parenchymal blood flow, and…”
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