Search Results - "Bailey, Jason"
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Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons
Published in PloS one (2011)“…Overproduction of amyloid-β (Aβ) protein in the brain has been hypothesized as the primary toxic insult that, via numerous mechanisms, produces cognitive…”
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The acute and incremental thermal tolerance of Atlantic cod (Gadus morhua) families under normoxia and mild hypoxia
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-07-2019)“…Given climate change projections, the limited ability of fish reared in sea-cages to behaviourally thermoregulate, and that thermal tolerance may be heritable,…”
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Wolbachia infections in Anopheles gambiae cells: transcriptomic characterization of a novel host-symbiont interaction
Published in PLoS pathogens (01-02-2011)“…The endosymbiotic bacterium Wolbachia is being investigated as a potential control agent in several important vector insect species. Recent studies have shown…”
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GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease
Published in Journal of Alzheimer's disease (01-01-2010)“…Type 2 (T2) diabetes mellitus (DM) has been associated with an increased incidence of neurodegenerative disorders, including Alzheimer's disease (AD). Several…”
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Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis
Published in Gene (15-11-2011)“…Amyloid-β peptide (Aβ) plaque in the brain is the primary ( post mortem) diagnostic criterion of Alzheimer's disease (AD). The physiological role(s) of Aβ are…”
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novel effect of rivastigmine on pre-synaptic proteins and neuronal viability in a neurodegeneration model of fetal rat primary cortical cultures and its implication in Alzheimer's disease
Published in Journal of neurochemistry (01-02-2010)“…J. Neurochem. (2010) 112, 843-853. Alzheimer's disease (AD) is characterized by deposition of amyloid-β peptide plaque, disrupted amyloid-β-precursor protein…”
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Does Extended PET Acquisition in PET/MRI Rectal Cancer Staging Improve Results?
Published in American journal of roentgenology (1976) (01-10-2018)“…The purpose of this study was to determine if extended PET acquisition times in the pelvis during PET/MRI increase detection rates of potentially metastatic…”
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Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke
Published in The Journal of neuroscience (11-11-2015)“…Stroke is the world's leading cause of physiological disability, but there are currently no available agents that can be delivered early after stroke to…”
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Serologic and Cytokine Profiles of Children with Concurrent Cerebral Malaria and Severe Malarial Anemia Are Distinct from Other Subtypes of Severe Malaria
Published in The American journal of tropical medicine and hygiene (17-08-2022)“…We used a protein microarray featuring Plasmodium falciparum field variants of a merozoite surface antigen to examine malaria exposure in Malian children with…”
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HIV PrEP is more than ART‐lite: Longitudinal study of real‐world PrEP services data identifies missing measures meaningful to HIV prevention programming
Published in Journal of the International AIDS Society (01-10-2021)“…Introduction Evidence indicates HIV oral pre‐exposure prophylaxis (PrEP) is highly efficacious and effective. Substantial early discontinuation rates are…”
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Children with hemoglobin C or S trait have low serologic responses to a subset of malaria variant surface antigens
Published in The Journal of infection (01-10-2024)“…Children with hemoglobin AC or AS have decreased susceptibility to clinical malaria. Parasite variant surface antigen (VSA) presentation on the surface of…”
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Memantine lowers amyloid-β peptide levels in neuronal cultures and in APP/PS1 transgenic mice
Published in Journal of neuroscience research (01-01-2010)“…Memantine is a moderate‐affinity, uncompetitive N‐methyl‐D‐aspartate (NMDA) receptor antagonist that stabilizes cognitive, functional, and behavioral decline…”
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Thermal biology and swimming performance of Atlantic cod ( Gadus morhua ) and haddock ( Melanogrammus aeglefinus )
Published in PeerJ (San Francisco, CA) (01-10-2019)“…Atlantic cod ( Gadus morhua ) and haddock ( Melanogrammus aeglefinus ) are two commercially important marine fishes impacted by both overfishing and climate…”
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Antenatal, intrapartum and infant azithromycin to prevent stillbirths and infant deaths: study protocol for SANTE, a 2×2 factorial randomised controlled trial in Mali
Published in BMJ open (30-08-2023)“…Introduction In high mortality settings, prophylactic azithromycin has been shown to improve birth weight and gestational age at birth when administered…”
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Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation
Published in Scientific reports (13-07-2021)“…Plasmodium falciparum erythrocyte membrane protein-1s (PfEMP1s), diverse malaria proteins expressed on the infected erythrocyte surface, play an important role…”
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Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets
Published in Scientific reports (19-04-2018)“…Variant surface antigens (VSAs) play a critical role in severe malaria pathogenesis. Defining gaps, or “lacunae”, in immunity to these Plasmodium falciparum…”
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Utility of Pelvic CT for Surveillance of T2-T4 Renal Cell Carcinoma After Nephrectomy With Curative Intent
Published in American journal of roentgenology (1976) (01-05-2018)“…The purpose of this study was to determine whether routine pelvic imaging is necessary during postoperative surveillance of pathologic T2-T4 renal cell…”
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Do Deauville Scores Improve the Clinical Utility of End-of-Therapy FDG PET Scans for Pediatric Hodgkin Lymphoma?
Published in American journal of roentgenology (1976) (01-02-2019)“…The purpose of this study was to evaluate the clinical utility of Deauville scores in interpretation of end-of-chemotherapy FDG PET scans. Deauville scores…”
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Serotonin Regulates Mammary Gland Development via an Autocrine-Paracrine Loop
Published in Developmental cell (01-02-2004)“…Mammary gland development is controlled by a dynamic interplay between endocrine hormones and locally produced factors. Biogenic monoamines (serotonin,…”
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Epitope-Specific Antibody Responses to a Plasmodium falciparum Subunit Vaccine Target in a Malaria-Endemic Population
Published in The Journal of infectious diseases (04-06-2021)“…Abstract Circumsporozoite protein (CSP) coats the Plasmodium falciparum sporozoite surface and is a major malaria subunit vaccine target. We measured…”
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