Search Results - "Bailey, Henry"

Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism by Fox, Nicholas G., Yu, Xiaodi, Feng, Xidong, Bailey, Henry J., Martelli, Alain, Nabhan, Joseph F., Strain-Damerell, Claire, Bulawa, Christine, Yue, Wyatt W., Han, Seungil

“…The core machinery for de novo biosynthesis of iron-sulfur clusters (ISC), located in the mitochondria matrix, is a five-protein complex containing the…”
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Structural Basis of an Asymmetric Condensin ATPase Cycle by Hassler, Markus, Shaltiel, Indra A., Kschonsak, Marc, Simon, Bernd, Merkel, Fabian, Thärichen, Lena, Bailey, Henry J., Macošek, Jakub, Bravo, Sol, Metz, Jutta, Hennig, Janosch, Haering, Christian H.

“…The condensin protein complex plays a key role in the structural organization of genomes. How the ATPase activity of its SMC subunits drives large-scale…”
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Construction and in vivo assembly of a catalytically proficient and hyperthermostable de novo enzyme by Watkins, Daniel W., Jenkins, Jonathan M. X., Grayson, Katie J., Wood, Nicola, Steventon, Jack W., Le Vay, Kristian K., Goodwin, Matthew I., Mullen, Anna S., Bailey, Henry J., Crump, Matthew P., MacMillan, Fraser, Mulholland, Adrian J., Cameron, Gus, Sessions, Richard B., Mann, Stephen, Anderson, J. L. Ross

“…Although catalytic mechanisms in natural enzymes are well understood, achieving the diverse palette of reaction chemistries in re-engineered native proteins…”
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The EQ-5D-5L valuation study for Trinidad and Tobago by Bailey, Henry, Jonker, Marcel F, Pullenayegum, Eleanor, Rencz, Fanni, Roudijk, Bram

“…The 2016 EQ-5D-3L value set for Trinidad and Tobago (T&T) allows for the calculation of EQ-5D-5L values via the crosswalk algorithm. The 2016 value set was…”
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The impact of chronic disease and accompanying bio-psycho-social factors on health-related quality of life by Bahall, Mandreker, Bailey, Henry

“…Background: Most chronic illnesses lead to poor health outcomes. Bio-psycho-social sequelae and accompanying depression lead to further deterioration in…”
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Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release by Bailey, Henry J., Bezerra, Gustavo A., Marcero, Jason R., Padhi, Siladitya, Foster, William R., Rembeza, Elzbieta, Roy, Arijit, Bishop, David F., Desnick, Robert J., Bulusu, Gopalakrishnan, Dailey, Harry A., Yue, Wyatt W.

“…5′-aminolevulinate synthase (ALAS) catalyzes the first step in heme biosynthesis, generating 5′-aminolevulinate from glycine and succinyl-CoA. Inherited…”
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EQ-5D-5L population norms and health inequalities for Trinidad and Tobago by Bailey, Henry, Janssen, Mathieu F, La Foucade, Althea, Kind, Paul

“…The EQ-5D instrument is now used in many health systems as a health outcomes measure. Recently an EQ-5D valuation study was conducted for Trinidad and Tobago,…”
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Architecture and regulation of filamentous human cystathionine beta-synthase by McCorvie, Thomas J., Adamoski, Douglas, Machado, Raquel A. C., Tang, Jiazhi, Bailey, Henry J., Ferreira, Douglas S. M., Strain-Damerell, Claire, Baslé, Arnaud, Ambrosio, Andre L. B., Dias, Sandra M. G., Yue, Wyatt W.

“…Cystathionine beta-synthase (CBS) is an essential metabolic enzyme across all domains of life for the production of glutathione, cysteine, and hydrogen…”
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Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis by Bilyard, Matthew K., Bailey, Henry J., Raich, Lluís, Gafitescu, Maria A., Machida, Takuya, Iglésias-Fernández, Javier, Lee, Seung Seo, Spicer, Christopher D., Rovira, Carme, Yue, Wyatt W., Davis, Benjamin G.

“…Biosynthesis of glycogen, the essential glucose (and hence energy) storage molecule in humans, animals and fungi 1 , is initiated by the glycosyltransferase…”
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Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein by Oerum, Stephanie, Roovers, Martine, Leichsenring, Michael, Acquaviva-Bourdain, Cécile, Beermann, Frauke, Gemperle-Britschgi, Corinne, Fouilhoux, Alain, Korwitz-Reichelt, Anne, Bailey, Henry J., Droogmans, Louis, Oppermann, Udo, Sass, Jörn Oliver, Yue, Wyatt W.

“…MRPP2 (also known as HSD10/SDR5C1) is a multifunctional protein that harbours both catalytic and non-catalytic functions. The protein belongs to the…”
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Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase by Sokolovskaya, Olga M., Plessl, Tanja, Bailey, Henry, Mackinnon, Sabrina, Baumgartner, Matthias R., Yue, Wyatt W., Froese, D. Sean, Taga, Michiko E.

“…Cobalamin, commonly known as vitamin B12, is an essential micronutrient for humans because of its role as an enzyme cofactor. Cobalamin is one of over a dozen…”
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EQ-5D self-reported health in Barbados and Jamaica with EQ-5D-5L population norms for the English-speaking Caribbean by Bailey, Henry, Janssen, Mathieu F, La Foucade, Althea, Boodraj, Girjanauth, Wharton, Marjorie, Castillo, Philip

“…The EQ-5D instrument is increasingly used in clinical and resource allocation decision making in developed and developing countries. EQ-5D valuation and…”
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Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes by Oerum, Stephanie, Roovers, Martine, Rambo, Robert P., Kopec, Jola, Bailey, Henry J., Fitzpatrick, Fiona, Newman, Joseph A., Newman, William G., Amberger, Albert, Zschocke, Johannes, Droogmans, Louis, Oppermann, Udo, Yue, Wyatt W.

“…Mitochondrial tRNAs are transcribed as long polycistronic transcripts of precursor tRNAs and undergo posttranscriptional modifications such as endonucleolytic…”
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Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism by Bezerra, Gustavo A, Foster, William R, Bailey, Henry J, Hicks, Kevin G, Sauer, Sven W, Dimitrov, Bianca, McCorvie, Thomas J, Okun, Jürgen G, Rutter, Jared, Kölker, Stefan, Yue, Wyatt W

“…DHTKD1 is a lesser-studied E1 enzyme among the family of 2-oxoacid de-hydrogenases. In complex with E2 (di-hydro-lipo-amide succinyltransferase, DLST) and E3…”
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Improving Population Health through Priority Setting in Trinidad and Tobago by Bailey, Henry, Espinoza, Manuel, Parkin, David, Smith, Stewart, Theodore, Karl

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Genetic, structural, and functional analysis of pathogenic variations causing methylmalonyl-CoA epimerase deficiency by Heuberger, Kathrin, Bailey, Henry J., Burda, Patricie, Chaikuad, Apirat, Krysztofinska, Ewelina, Suormala, Terttu, Bürer, Céline, Lutz, Seraina, Fowler, Brian, Froese, D. Sean, Yue, Wyatt W., Baumgartner, Matthias R.

“…Human methylmalonyl-CoA epimerase (MCEE) catalyzes the interconversion of d-methylmalonyl-CoA and l-methylmalonyl-CoA in propionate catabolism. Autosomal…”
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Evaluating Health Inequality in Five Caribbean Basin Countries Using EQ-5D-5L by Bailey, Henry H., Janssen, Mathieu F., Alladin, Fareena M., La Foucade, Althea, Varela, Rodrigo, Moreno, Jhon A., Wharton, Marjorie, Castillo, Philip, Boodraj, Girjanauth

“…Background EQ-5D-5L is a standardized health outcomes instrument that can be added to national surveys to measure inequality in health outcomes. The aim of…”
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Preliminary findings of an investigation into the relationship between national culture and EQ-5D value sets by Bailey, Henry, Kind, Paul

“…Background Despite the growing importance of the EQ-5D descriptive system as a basis for the valuation of QALYs in cost-utility analysis, for most countries,…”
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The EQ-5D-3L valuation study for Bermuda: using an on-line EQ-VT protocol by Bailey, Henry, Roudijk, Bram, Brathwaite, Ricky

“…In many countries, methods of economic evaluation and Health Technology Assessment are used to inform healthcare resource allocation decisions. These…”
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EQ-5D-3L Population Norms for Trinidad and Tobago by Bailey, Henry H

“…ABSTRACT Objective Quality of life measures are increasingly being used in clinical practice and in research. Internationally EQ-5D is the most commonly used…”
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