Search Results - "Bailey, Dianna L."

Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis by Heuer, Josef G, Sharma, Ganesh R, Gerlitz, Bruce, Zhang, Tonghai, Bailey, Dianna L, Ding, Chunjin, Berg, David T, Perkins, Douglas, Stephens, Eddie J, Holmes, Kimberly C, Grubbs, Renee L, Fynboe, Kelly A, Chen, Yun-Fei, Grinnell, Brian, Jakubowski, Joseph A

“…OBJECTIVE:To evaluate protein C and other factors associated with the septic response as predictors of mortality in a clinically relevant animal model of…”
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Cecal ligation and puncture with total parenteral nutrition: A clinically relevant model of the metabolic, hormonal, and inflammatory dysfunction associated with critical illness by Heuer, Josef G., Bailey, Dianna L., Sharma, Ganesh R., Zhang, Tonghai, Ding, Chunjin, Ford, Amy, Stephens, Eddie J., Holmes, Kimberly C., Grubbs, Renee L., Fynboe, Kelly A., Chen, Yun-Fei, Jakubowski, Joseph A.

“…Standard rat cecal ligation and puncture (CLP) results in only transient hyperglycemia, making an examination of the effects of glucoregulatory agents, such as…”
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Effects of Hyperglycemia and Insulin Therapy on Outcome in a Hyperglycemic Septic Model of Critical Illness by Heuer, Josef G., Sharma, Ganesh R., Zhang, Tonghai, Ding, Chunjin, Bailey, Dianna L., Stephens, Eddie J., Holmes, Kimberly C., Grubbs, Renee L., Fynboe, Kelly A., Chen, Yun-Fei, Jakubowski, Joseph A.

“…BACKGROUND:The effects of hyperglycemia and insulin therapy on septic outcome have not been well studied. METHODS:Septic hyperglycemia was induced by infusion…”
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Diamino Benzo[b]thiophene Derivatives as a Novel Class of Active Site Directed Thrombin Inhibitors. 5. Potency, Efficacy, and Pharmacokinetic Properties of Modified C-3 Side Chain Derivatives by Sall, Daniel J, Bailey, Dianna L, Bastian, Jolie A, Buben, John A, Chirgadze, Nickolay Y, Clemens-Smith, Amy C, Denney, Michael L, Fisher, Matthew J, Giera, Deborah D, Gifford-Moore, Donetta S, Harper, Richard W, Johnson, Lea M, Klimkowski, Valentine J, Kohn, Todd J, Lin, Ho-Shen, McCowan, Jefferson R, Palkowitz, Alan D, Richett, Michael E, Smith, Gerald F, Snyder, David W, Takeuchi, Kumiko, Toth, John E, Zhang, Minsheng

“…A systematic investigation of the structure−activity relationships of the C-3 side chain of the screening hit 1a led to the identification of the potent…”
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Dibasic benzo[ b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2: sidechain optimization and demonstration of in vivo efficacy by Zhang, Minsheng, Bailey, Dianna L., Bastian, Jolie A., Briggs, Stephen L., Chirgadze, Nickolay Y., Clawson, David K., Denney, Michael L., Gifford-Moore, Donetta S., Harper, Richard W., Johnson, Lea M., Klimkowski, Valentine J., Kohn, Todd J., Lin, Ho-Shen, McCowan, Jefferson R., Richett, Michael E., Sall, Daniel J., Smith, Amy J., Smith, Gerald F., Snyder, David W., Takeuchi, Kumiko, Utterback, Barbara G., Yan, Sau-Chi B.

“…Potent, subnanomolar thrombin inhibitors 4, 5, and 6 are developed through side chain optimization of novel, benzo[ b]thiophene-based small organic entities 2…”
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