Search Results - "Bailey, Dale L"
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An evidence-based review of quantitative SPECT imaging and potential clinical applications
Published in Journal of Nuclear Medicine (01-01-2013)“…SPECT has traditionally been regarded as nonquantitative. Advances in multimodality γ-cameras (SPECT/CT), algorithms for image reconstruction, and…”
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A prospective randomized multicentre study of the impact of gallium‐68 prostate‐specific membrane antigen (PSMA) PET/CT imaging for staging high‐risk prostate cancer prior to curative‐intent surgery or radiotherapy (proPSMA study): clinical trial protocol
Published in BJU international (01-11-2018)“…Background Accurate staging of patients with prostate cancer (PCa) is important for therapeutic decision‐making. Relapse after surgery or radiotherapy of…”
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Quantitative PET in the 2020s: a roadmap
Published in Physics in medicine & biology (12-03-2021)“…Positron emission tomography (PET) plays an increasingly important role in research and clinical applications, catalysed by remarkable technical advances and a…”
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Accuracy of Dose Calibrators for 68Ga PET Imaging: Unexpected Findings in a Multicenter Clinical Pretrial Assessment
Published in The Journal of nuclear medicine (1978) (01-04-2018)“…We report the discovery of a systematic miscalibration during the work-up process for site validation of a multicenter clinical PET imaging trial using 68Ga,…”
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Quantitative and qualitative assessment of Yttrium-90 PET/CT imaging
Published in PloS one (04-11-2014)“…Yttrium-90 is known to have a low positron emission decay of 32 ppm that may allow for personalized dosimetry of liver cancer therapy with (90)Y labeled…”
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Individualised dosimetry and safety of SIRT for intrahepatic cholangiocarcinoma
Published in EJNMMI physics (14-09-2021)“…Background The aim of this study was to investigate the safety and efficacy of selective internal radiation therapy (SIRT) with 90 Y resin microspheres for the…”
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Overlooked potential of positrons in cancer therapy
Published in Scientific reports (28-01-2021)“…Positron (β + ) emitting radionuclides have been used for positron emission tomography (PET) imaging in diagnostic medicine since its development in the 1950s…”
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The MANGO study: a prospective investigation of oxygen enhanced and blood-oxygen level dependent MRI as imaging biomarkers of hypoxia in glioblastoma
Published in Frontiers in oncology (19-12-2023)“…Glioblastoma (GBM) is the most aggressive type of brain cancer, with a 5-year survival rate of ~5% and most tumours recurring locally within months of…”
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Towards personalised dosimetry in patients with liver malignancy treated with 90Y-SIRT using in vivo-driven radiobiological parameters
Published in EJNMMI physics (30-07-2022)“…Background The prediction of response is one of the major challenges in radiation-based therapies. Although the selection of accurate linear–quadratic model…”
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Not All Gatekeepers Are Theranostics
Published in Journal of Nuclear Medicine (01-10-2023)Get full text
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Radiopharmaceutical Extravasations Can Have Consequences
Published in Journal of Nuclear Medicine (01-08-2023)Get full text
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[ 18 F]-fluoroethyl-L-tyrosine (FET) in glioblastoma (FIG) TROG 18.06 study: protocol for a prospective, multicentre PET/CT trial
Published in BMJ open (04-08-2023)“…Glioblastoma is the most common aggressive primary central nervous system cancer in adults characterised by uniformly poor survival. Despite maximal safe…”
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Clinical and imaging-based prognostic factors in radioembolisation of liver metastases from colorectal cancer: a retrospective exploratory analysis
Published in EJNMMI research (23-05-2017)“…Background The aim of this study was to investigate the relationship between absorbed dose and response of colorectal cancer liver metastases treated with [ 90…”
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Investigation and optimization of PET-guided SPECT reconstructions for improved radionuclide therapy dosimetry estimates
Published in Frontiers in nuclear medicine (2023)“…To investigate and optimize the SPECTRE (Single Photon Emission Computed Theranostic REconstruction) reconstruction approach, using the hybrid kernelised…”
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Pulmonary hypertension leads to a loss of gravity dependent redistribution of regional lung perfusion: a SPECT/CT study
Published in Heart (British Cardiac Society) (01-01-2014)“…Pre-capillary pulmonary hypertension (PHT) is characterised by progressive pulmonary vascular obliteration and loss of vascular reserves. In health, regional…”
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Artifacts and Anatomical Variants Affecting Ventilation and Perfusion Lung Imaging
Published in Seminars in nuclear medicine (01-09-2015)“…Ventilation and perfusion lung imaging continues to be an important technique in the investigation of lung disease, particularly pulmonary emboli. For the most…”
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Quantitative SPECT/CT: SPECT joins PET as a quantitative imaging modality
Published in European journal of nuclear medicine and molecular imaging (01-05-2014)“…The introduction of combined modality single photon emission computed tomography (SPECT)/CT cameras has revived interest in quantitative SPECT. Schemes to…”
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SPECT/CT in V/Q Scanning
Published in Seminars in nuclear medicine (01-11-2010)“…Combining the functional data provided by single-photon emission computed tomography (SPECT) with the anatomical information provided by CT has been shown to…”
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Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study
Published in The lancet oncology (01-10-2017)“…TargomiRs are minicells (EnGeneIC Dream Vectors) loaded with miR-16-based mimic microRNA (miRNA) and targeted to EGFR that are designed to counteract the loss…”
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Enhancing Lung Scintigraphy With Single-Photon Emission Computed Tomography
Published in Seminars in nuclear medicine (01-11-2008)“…Although widely used for many years in the assessment of pulmonary embolism, planar ventilation-perfusion (V/Q) scintigraphy has well-recognized limitations…”
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