Search Results - "Bailey, D G"

Naringin is a Major and Selective Clinical Inhibitor of Organic Anion-Transporting Polypeptide 1A2 (OATP1A2) in Grapefruit Juice by Bailey, D G, Dresser, G K, Leake, B F, Kim, R B

“…We showed previously that grapefruit and orange juices inhibited human enteric organic anion‐transporting polypeptide (OATP)1A2 in vitro and lowered oral…”
Get full text

Intestinal Drug Transporter Expression and the Impact of Grapefruit Juice in Humans by Glaeser, H, Bailey, D G, Dresser, G K, Gregor, J C, Schwarz, U I, McGrath, J S, Jolicoeur, E, Lee, W, Leake, B F, Tirona, R G, Kim, R B

“…The goals of this study were to assess the extent of human intestinal drug transporter expression, determine the subcellular localization of the drug uptake…”
Get full text

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition by DRESSER, G. K, SPENCE, J. D, BAILEY, D. G

“…Drug interactions occur when the efficacy or toxicity of a medication is changed by administration of another substance. Pharmacokinetic interactions often…”
Get full text

The effects of fruit juices on drug disposition: a new model for drug interactions by Dresser, G. K., Bailey, D. G.

“…Grapefruit juice produces mechanism‐based inhibition of intestinal drug metabolism when consumed in normal quantities. This can produce clinically important…”
Get full text

Grapefruit juice–drug interactions by Bailey, David G., Malcolm, J., Arnold, O., David Spence, J.

“…The novel finding that grapefruit juice can markedly augment oral drug bioavailability was based on an unexpected observation from an interaction study between…”
Get full text

Geochemical Constraints on the Origin of Volcanic Rocks from the Andean Northern Volcanic Zone, Ecuador by BRYANT, J. A., YOGODZINSKI, G. M., HALL, M. L., LEWICKI, J. L., BAILEY, D. G.

“…Whole-rock geochemical data on basaltic to rhyolitic samples from 12 volcanic centers are used to constrain the role of continental crust in the genesis of…”
Get full text

Predicting clinical relevance of grapefruit–drug interactions: a complicated process by Bailey, D. G.

“…Summary What is known and objective Grapefruit juice interacts with a number of drugs. This commentary provides feedback on a previously proposed approach for…”
Get full text

Sorption of Cr(VI) from aqueous solution by Amberlite XAD-7 resin impregnated with Aliquat 336 by Saha, B, Gill, R.J, Bailey, D.G, Kabay, N, Arda, M

“…This work investigates the removal of chromium (VI) from aqueous solution using solvent impregnated resins (SIR). SIR have been formed by impregnating…”
Get full text

Natural products and adverse drug interactions by Bailey, David G, Dresser, George K

“…St. John's wort, a herb that has become popular in the treatment of depression, has the opposite effect. It increases the activity of CYP3A4, thereby causing…”
Get full text

Preferential transcription of the mutated allele in NPM1 mutated acute myeloid leukaemia by Bailey, G. D., Doolan, L., Baskar, A., Smith, L. C., Seedhouse, C. H.

“…Nucleophosmin is commonly both over-expressed and mutated in acute myeloid leukemia (AML). NPM1 mutations are always heterozygous. In addition, NPM1 has a…”
Get full text

Improved diagnosis of virulent ovine footrot using the intA gene by Cheetham, B.F., Tanjung, L.R., Sutherland, M., Druitt, J., Green, G., McFarlane, J., Bailey, G.D., Seaman, J.T., Katz, M.E.

“…Footrot is a mixed bacterial infection of the hooves of sheep. The Gram-negative anaerobic bacterium Dichelobacter nodosus is the principal causative agent,…”
Get full text

A generalized multi-scale line-detection method to boost retinal vessel segmentation sensitivity by Khan, Mohammad A. U., Khan, Tariq M., Bailey, D. G., Soomro, Toufique A.

“…Many chronic eye diseases can be conveniently investigated by observing structural changes in retinal blood vessel diameters. However, detecting changes in an…”
Get full text

Grapefruit juice-felodipine interaction: Effect of naringin and 6′,7′-dihydroxybergamottin in humans by Bailey, David G., Kreeft, John H., Munoz, Claudio, Freeman, David J., Bend, John R.

“…Objective To test whether naringin or 6′,7′‐dihydroxybergamottin is a major active substance in grape‐fruit juice‐felodipine interaction in humans. Methods…”
Get full text

Grapefruit juice-felodipine interaction : reproducibility and characterization with the extended release drug formulation by BAILEY, D. G, ARNOLD, J. M. O, BEND, J. R, TRAN, L. T, SPENCE, J. D

“…1. Felodipine 10 mg extended release was administered with 250 ml regular-strength grapefruit juice or water in a randomized crossover manner followed by a…”
Get full text

Grapefruit juice-terfenadine single-dose interaction: Magnitude, mechanism, and relevance by Rau, Susan E., Bend, John R., Arnold, J. Malcolm O., Tran, Lan T., Spence, J. David, Bailey, David G.

“…Objective To investigate the single dose‐response effects of grapefruit juice on terfenadine disposition and electrocardiographic measurements. Methods Twelve…”
Get full text

Grapefruit juice and drugs : how significant is the interaction ? by BAILEY, D. G, ARNOLD, J. M. O, SPENCE, J. D

Get full text

Geochemical Constraints on the Origin of Volcanic Rocks from the Andean Northern Volcanic Zone, Ecuador by Bryant, J A, Yogodzinski, G M, Hall, M L, Lewicki, J L, Bailey, D G

“…Whole-rock geochemical data on basaltic to rhyolitic samples from 12 volcanic centers are used to constrain the role of continental crust in the genesis of…”
Get full text

Salmonella and on-farm risk factors in healthy slaughter-age cattle and sheep in eastern Australia by Vanselow, BA, Hornitzky, MA, Walker, KH, Eamens, GJ, Bailey, GD, Gill, PA, Coates, K, Corney, B, Cronin, JP, Renilson, S

“…Objective   To examine healthy slaughter‐age cattle and sheep on‐farm for the excretion of Salmonella serovars in faeces and to identify possible risk factors…”
Get full text

GASH VEINS NEAR BIGELOW, ST. LAWRENCE COUNTY, NEW YORK by Chamberlain, S C, Bailey, D G, Carlin, D M

“…As part of ongoing study of so-called gash veins (GV) in St. Lawrence County NY, a cluster of these veins have been discovered just southeast of Bigelow. These…”
Get full text

Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice by Bailey, D G, Bend, J R, Arnold, J M, Tran, L T, Spence, J D

“…To investigate a potentially marked effect by erythromycin on felodipine pharmacokinetics, to characterize the mechanism, and to compare the interaction with…”
Get more information