Search Results - "Baig, S. M."
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1
ACE inhibitors, angiotensin receptor blockers and endothelial injury in COVID‐19
Published in Journal of internal medicine (01-05-2021)“…Background COVID‐19 is caused by the coronavirus SARS‐CoV‐2, which uses angiotensin‐converting enzyme 2 (ACE‐2) as a receptor for cellular entry. It is…”
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2
Identification of novel inhibitors targeting TIRAP interactions with BTK and PKCδ in inflammation through an in silico approach
Published in SAR and QSAR in environmental research (04-03-2022)“…Advanced computational tools focusing on protein-protein interaction (PPI) based drug development is a powerful platform to accelerate the therapeutic…”
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3
Microduplications encompassing the Sonic hedgehog limb enhancer ZRS are associated with Haas-type polysyndactyly and Laurin-Sandrow syndrome
Published in Clinical genetics (01-10-2014)“…Laurin‐Sandrow syndrome (LSS) is a rare autosomal dominant disorder characterized by polysyndactyly of hands and/or feet, mirror image duplication of the feet,…”
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4
Homozygosity for a missense variant in COMP gene associated with severe pseudoachondroplasia
Published in Clinical genetics (01-01-2018)“…The phenotypic spectrum associated with heterozygous mutations in cartilage oligomeric matrix protein gene (COMP) range from a mild form of multiple epiphyseal…”
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5
Genetic heterogeneity in Pakistani microcephaly families
Published in Clinical genetics (01-05-2013)“…Autosomal recessive primary microcephaly (MCPH) is caused by mutations in at least eight different genes involved either in cell division or DNA repair. Most…”
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6
Cerebral involvement in benign tertian malaria
Published in The American journal of tropical medicine and hygiene (01-09-2002)“…Although Plasmodium vivax usually causes benign uncomplicated malaria, it can occasionally result in severe disease with life-threatening, end-organ…”
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7
Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2,3-dioxygenase involved in degradation of polychlorinated biphenyls
Published in International journal of biological macromolecules (2010)“…Biphenyl dioxygenase is a microbial enzyme which catalyzes the stereospecific dioxygenation of aromatic rings of biphenyl congeners leading to their…”
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8
Identifying the inhibition of TIR proteins involved in TLR signalling as an anti-inflammatory strategy
Published in SAR and QSAR in environmental research (03-04-2018)“…Toll/IL1 receptor (TIR) adaptor proteins continue to be an integral part of Toll-like receptors' (TLR) signalling involved in inflammation. Signalling is…”
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9
Time domain diversity combining with delay-and-advanced operation in two layered asymmetrically clipped optical OFDM system
Published in Optical and quantum electronics (01-07-2022)“…This paper demonstrates the advantage of application of time domain diversity combining (TDDC) at the transmitter over the time domain diversity combining…”
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10
Prediction of viral loads for diagnosis of Hepatitis C infection in human plasma samples using Raman spectroscopy coupled with partial least squares regression analysis
Published in Journal of Raman spectroscopy (01-05-2017)“…Raman spectroscopy has been used to identify the biochemical changes associated with the presence of the Hepatitis C virus (HCV) in infected human blood plasma…”
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11
Human cervicovaginal mucus contains an activity that hinders HIV-1 movement
Published in Mucosal immunology (01-03-2013)“…Cervical and vaginal epithelia are primary barriers against HIV type I (HIV-1) entry during male-to-female transmission. Cervical mucus (CM) is produced by the…”
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12
Genetic heterogeneity in Pakistani microcephaly families revisited
Published in Clinical genetics (01-07-2017)“…Autosomal recessive primary microcephaly (MCPH) is a rare and heterogeneous genetic disorder characterized by reduced head circumference, low cognitive prowess…”
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13
Ischemic Stroke subtypes in Pakistan: The Aga Khan University Stroke data bank
Published in Journal of the Pakistan Medical Association (01-12-2003)“…Frequency of ischemic stroke subtypes is influenced by ethnic and geographic variables. Our objective was to identify various stroke subtypes and its…”
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14
Probing PARP1-inhibitor complexes for the development of novel inhibitors
Published in Cellular and molecular biology (Noisy-le-Grand, France) (25-10-2014)“…Poly (ADP-ribose) polymerase 1 (PARP1) is the most important member of the PARP family which has been shown to have a direct involvement in the development of…”
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15
Biochemical characterization of dipeptidylcarboxypeptidase of Leishmania donovani
Published in Cellular and molecular biology (Noisy-le-Grand, France) (12-02-2011)“…The incidence of parasitic infection, leishmaniasis, has been steadily increasing worldwide. Since, the existing chemotherapy of these diseases suffers from…”
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16
Molecular and population genetic analyses of β‐Thalassemia in Turkey
Published in American journal of hematology (01-03-1998)“…In this report we describe the molecular analysis of 795 chromosomes derived from unrelated Turkish β‐thalassemia and sickle cell anemia carriers identified in…”
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17
Cenani–Lenz syndrome restricted to limb and kidney anomalies associated with a novel LRP4 missense mutation
Published in European journal of medical genetics (01-07-2013)“…Abstract Cenani–Lenz syndrome (CLS) is a rare autosomal recessive developmental disorder of the limbs. The disorder is characterized by complete syndactyly…”
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18
Identifying human disease genes: advances in molecular genetics and computational approaches
Published in Genetics and molecular research (04-07-2014)“…The human genome project is one of the significant achievements that have provided detailed insight into our genetic legacy. During the last two decades,…”
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Spectrum of complications and mortality of Bacterial meningitis: an experience from a developing country
Published in Journal of the Pakistan Medical Association (01-12-2003)“…The aim of this study was to obtain data on predisposing factors, causative organisms and their associated mortality and complications related to acute…”
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20
Anti-purified protein derivative cell-enzyme-linked immunosorbent assay, a sensitive method for early diagnosis of tuberculous meningitis
Published in Journal of Clinical Microbiology (01-11-1995)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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