Search Results - "Baid, Rinku"

Modifier genes as therapeutics: the nuclear hormone receptor Rev Erb alpha (Nr1d1) rescues Nr2e3 associated retinal disease by Cruz, Nelly M, Yuan, Yang, Leehy, Barrett D, Baid, Rinku, Kompella, Uday, DeAngelis, Margaret M, Escher, Pascal, Haider, Neena B

“…Nuclear hormone receptors play a major role in many important biological processes. Most nuclear hormone receptors are ubiquitously expressed and regulate…”
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LEDGF(1-326) decreases P23H and wild type rhodopsin aggregates and P23H rhodopsin mediated cell damage in human retinal pigment epithelial cells by Baid, Rinku, Scheinman, Robert I, Shinohara, Toshimichi, Singh, Dhirendra P, Kompella, Uday B

“…P23H rhodopsin, a mutant rhodopsin, is known to aggregate and cause retinal degeneration. However, its effects on retinal pigment epithelial (RPE) cells are…”
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Investigating thiol‐modification on hyaluronan via carbodiimide chemistry using response surface methodology by Santhanam, Sruthi, Liang, Jue, Baid, Rinku, Ravi, Nathan

“…Hyaluronan (HA) is a naturally occurring glycosaminoglycan widely researched for its use as a biomaterial in tissue engineering, drug delivery, angiogenesis,…”
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Critical considerations for developing nucleic acid macromolecule based drug products by Muralidhara, Bilikallahalli K., Baid, Rinku, Bishop, Steve M., Huang, Min, Wang, Wei, Nema, Sandeep

“…•Increased emphasis in recent years on DNA/mRNA macromolecule-based therapeutic drugs.•Formulation excipients and their role in increasing the drug product…”
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Investigating thiol-modification on hyaluronan via carbodiimide chemistry using response surface methodology: Investigating Thiolation of HA Using RSM by Santhanam, Sruthi, Liang, Jue, Baid, Rinku, Ravi, Nathan

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Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cells by Sreekumar, Parameswaran G, Chothe, Paresh, Sharma, Krishna K, Baid, Rinku, Kompella, Uday, Spee, Christine, Kannan, Nandini, Manh, Christina, Ryan, Stephen J, Ganapathy, Vadivel, Kannan, Ram, Hinton, David R

“…The chaperone proteins, α-crystallins, also possess antiapoptotic properties. The purpose of the present study was to investigate whether 19 to 20-mer…”
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Critical considerations for developing nucleic acid macromolecule based drug products: Foundation by Muralidhara, Bilikallahalli K, Baid, Rinku, Bishop, Steve M, Huang, Min, Wang, Wei, Nema, Sandeep

“…Protein expression therapy using nucleic acid macromolecules (NAMs) as a new paradigm in medicine has recently gained immense therapeutic potential. With the…”
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Biosynthesis, Characterization, and Efficacy in Retinal Degenerative Diseases of Lens Epithelium-derived Growth Factor Fragment (LEDGF1–326), a Novel Therapeutic Protein by Baid, Rinku, Upadhyay, Arun K., Shinohara, Toshimichi, Kompella, Uday B.

“…For vision-threatening retinitis pigmentosa and dry age-related macular degeneration, there are no United States Food and Drug Administration (FDA)-approved…”
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Modifier Genes as Therapeutics: The Nuclear Hormone Receptor Rev Erb Alpha by Cruz, Nelly M, Yuan, Yang, Leehy, Barrett D, Baid, Rinku, Kompella, Uday, DeAngelis, Margaret M, Escher, Pascal, Haider, Neena B

“…Nuclear hormone receptors play a major role in many important biological processes. Most nuclear hormone receptors are ubiquitously expressed and regulate…”
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LEDGF.sub.1-326 Decreases P23H and Wild Type Rhodopsin Aggregates and P23H Rhodopsin Mediated Cell Damage in Human Retinal Pigment Epithelial Cells by Baid, Rinku, Scheinman, Robert I, Shinohara, Toshimichi, Singh, Dhirendra P, Kompella, Uday B

“…Background P23H rhodopsin, a mutant rhodopsin, is known to aggregate and cause retinal degeneration. However, its effects on retinal pigment epithelial (RPE)…”
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Lens epithelium derived growth factor (1-326): A new protein drug for retinal diseases by Baid, Rinku

“…Although over 2.2 million people in the United States suffer from dry age related macular degeneration and retinitis pigmentosa, there are no FDA approved…”
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LEDGF1-326 Decreases P23H and Wild Type Rhodopsin Aggregates and P23H Rhodopsin Mediated Cell Damage in Human Retinal Pigment Epithelial Cells by Baid, Rinku, Scheinman, Robert I., Shinohara, Toshimichi, Singh, Dhirendra P., Kompella, Uday B.

“…Background P23H rhodopsin, a mutant rhodopsin, is known to aggregate and cause retinal degeneration. However, its effects on retinal pigment epithelial (RPE)…”
Get full text