Search Results - "Bai, XueLi"

Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy by Tang, Tianyu, Huang, Xing, Zhang, Gang, Hong, Zhengtao, Bai, Xueli, Liang, Tingbo

“…Despite great success in cancer immunotherapy, immune checkpoint-targeting drugs are not the most popular weapon in the armory of cancer therapy. Accumulating…”
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NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1 by Zhang, Xiaozhen, Huang, Xing, Xu, Jian, Li, Enliang, Lao, Mengyi, Tang, Tianyu, Zhang, Gang, Guo, Chengxiang, Zhang, Xiaoyu, Chen, Wen, Yadav, Dipesh Kumar, Bai, Xueli, Liang, Tingbo

“…Despite the substantial impact of post-translational modifications on programmed cell death 1 ligand 1 (PD-L1), its importance in therapeutic resistance in…”
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O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy by Lu, Qingsong, Zhang, Xiaozhen, Liang, Tingbo, Bai, Xueli

“…Abstract O -linked β- d - N -acetylglucosamine ( O -GlcNAc) is an important post-translational modification of serine or threonine residues on thousands of…”
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Existence and Uniqueness of Positive Solutions to Nonlinear Systems of Equations With M-Type Functions by Bai, Xueli

“…This paper considers the existence and uniqueness of positive solutions to a class of nonlinear systems of equations, which has wide applications in fluid…”
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Construction of a human cell landscape at single-cell level by Han, Xiaoping, Zhou, Ziming, Fei, Lijiang, Sun, Huiyu, Wang, Renying, Chen, Yao, Chen, Haide, Wang, Jingjing, Tang, Huanna, Ge, Wenhao, Zhou, Yincong, Ye, Fang, Jiang, Mengmeng, Wu, Junqing, Xiao, Yanyu, Jia, Xiaoning, Zhang, Tingyue, Ma, Xiaojie, Zhang, Qi, Bai, Xueli, Lai, Shujing, Yu, Chengxuan, Zhu, Lijun, Lin, Rui, Gao, Yuchi, Wang, Min, Wu, Yiqing, Zhang, Jianming, Zhan, Renya, Zhu, Saiyong, Hu, Hailan, Wang, Changchun, Chen, Ming, Huang, He, Liang, Tingbo, Chen, Jianghua, Wang, Weilin, Zhang, Dan, Guo, Guoji

“…Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex systems 1 . However, a comprehensive single-cell atlas has not been…”
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VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy by Huang, Xing, Zhang, Xiaozhen, Li, Enliang, Zhang, Gang, Wang, Xun, Tang, Tianyu, Bai, Xueli, Liang, Tingbo

“…VISTA (V-domain immunoglobulin suppressor of T cell activation) is a well-established immune regulatory receptor. However, pre-clinical investigations…”
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Optimization of total population in logistic model with nonlocal dispersals and heterogeneous environments by Bai, Xueli, Li, Fang, Zhou, Maolin

“…In this paper, we investigate the issue of maximizing the total equilibrium population with respect to resources distribution m ( x ) and diffusion rates d…”
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Single tumor-initiating cells evade immune clearance by recruiting type II macrophages by Guo, Xiaocan, Zhao, Yang, Yan, Huan, Yang, Yingcheng, Shen, Shuying, Dai, Xiaoming, Ji, Xinyan, Ji, Fubo, Gong, Xing-Guo, Li, Li, Bai, Xueli, Feng, Xin-Hua, Liang, Tingbo, Ji, Junfang, Chen, Lei, Wang, Hongyang, Zhao, Bin

“…Tumor infiltrated type II (M2) macrophages promote tumorigenesis by suppressing immune clearance, promoting proliferation, and stimulating angiogenesis…”
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Glucose Metabolism: The Metabolic Signature of Tumor Associated Macrophage by Zhang, Qi, Wang, Junli, Yadav, Dipesh Kumar, Bai, Xueli, Liang, Tingbo

“…Macrophages exist in most tissues of the body, where they perform various functions at the same time equilibrating with other cells to maintain immune…”
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The “Self-eating” of cancer-associated fibroblast: A potential target for cancer by Chen, Yan, Zhang, Xiaozhen, Yang, Hanshen, Liang, Tingbo, Bai, Xueli

“…Autophagy helps maintain energy homeostasis and protect cells from stress effects by selectively removing misfolded/polyubiquitylated proteins, lipids, and…”
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Hypoxia-inducible factor-2α promotes tumor progression and has crosstalk with Wnt/β-catenin signaling in pancreatic cancer by Zhang, Qi, Lou, Yu, Zhang, Jingying, Fu, Qihan, Wei, Tao, Sun, Xu, Chen, Qi, Yang, Jiaqi, Bai, Xueli, Liang, Tingbo

“…Pancreatic cancer is a devastating disease that is characterized by persistent hypoxia. The roles of hypoxia-inducible factor-2α (hif-2α) are different to…”
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PBX3 as a biomarker for the early diagnosis and prediction of prognosis of glioma by Pan, Cuicui, Bai, Xueli, Li, Na, Zheng, Ni, Si, Yuanquan, Zhao, Yueran

“…Increasing evidence have elucidated that PBX3 played a crucial role in cancer initiation and progression. PBX3 was differentially expressed in many cancer…”
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Neoadjuvant chemotherapy for primary resectable pancreatic cancer: a systematic review and meta-analysis by Ye, Mao, Zhang, Qi, Chen, Yiwen, Fu, Qihan, Li, Xiang, Bai, Xueli, Liang, Tingbo

“…Preoperative chemotherapy has shown benefits for locally advanced and borderline resectable pancreatic cancer. Neoadjuvant chemotherapy (NAC) has also been…”
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Molecular Profiling–Based Precision Medicine in Cancer: A Review of Current Evidence and Challenges by Zhang, Qi, Fu, Qihan, Bai, Xueli, Liang, Tingbo

“…Matched therapy based on next-generation sequencing is now a part of routine care to guide the treatment of patients with advanced solid tumors. However,…”
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RCAN1-mediated calcineurin inhibition as a target for cancer therapy by Lao, Mengyi, Zhang, Xiaozhen, Yang, Hanshen, Bai, Xueli, Liang, Tingbo

“…Abstract Cancer is the leading cause of mortality worldwide. Regulator of calcineurin 1 (RCAN1), as a patent endogenous inhibitor of calcineurin, plays crucial…”
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Targeting TNFR2: A Novel Breakthrough in the Treatment of Cancer by Li, Muchun, Zhang, Xiaozhen, Bai, Xueli, Liang, Tingbo

“…Tumor necrosis factor (TNF) receptor type II (TNFR2) is expressed in various tumor cells and some immune cells, such as regulatory T cells and myeloid-derived…”
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Blocking PD-L1 for anti-liver cancer immunity: USP22 represents a critical cotarget by Huang, Xing, Zhang, Xiaozhen, Bai, Xueli, Liang, Tingbo

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Combination therapy for pancreatic cancer: anti-PD-(L)1-based strategy by Liu, Lingyue, Huang, Xing, Shi, Fukang, Song, Jinyuan, Guo, Chengxiang, Yang, Jiaqi, Liang, Tingbo, Bai, Xueli

“…Mortality associated with pancreatic cancer is among the highest of all malignancies, with a 5-year overall survival of 5-10%. Immunotherapy, represented by…”
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Duct-to-Mucosa vs Invagination for Pancreaticojejunostomy after Pancreaticoduodenectomy: A Prospective, Randomized Controlled Trial from a Single Surgeon by Bai, Xueli, MD, PhD, Zhang, Qi, MD, Gao, Shunliang, MBBS, Lou, Jianying, MD, Li, Guogang, MD, Zhang, Yun, MD, PhD, Ma, Tao, MD, PhD, Zhang, Yibo, MD, Xu, Yuanliang, MBBS, Liang, Tingbo, MD, PhD, FACS

“…Background Pancreatic fistula (PF) is the most common significant complication after pancreaticoduodenectomy. Invagination and duct-to-mucosa anastomoses are…”
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Monitoring Tumor Burden in Response to FOLFIRINOX Chemotherapy Via Profiling Circulating Cell-Free DNA in Pancreatic Cancer by Wei, Tao, Zhang, Qi, Li, Xiang, Su, Wei, Li, Guogang, Ma, Tao, Gao, Shunliang, Lou, Jianying, Que, Risheng, Zheng, Lei, Bai, Xueli, Liang, Tingbo

“…We aimed to explore the application of circulating cell-free DNA (cfDNA) profiling in monitoring tumor burden in patients with pancreatic ductal adenocarcinoma…”
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