Search Results - "Bai, XingWen"

A quadruple recombination event discovered in hepatitis E virus by Shen, Hao, Liu, Shuning, Ding, Min, Gu, Haixia, Chang, Ming, Li, Yanshuang, Wang, Hua, Bai, Xingwen, Shen, Hongxing

“…Hepatitis E virus (HEV) can infect humans, pigs, and many other animals, but recombination in HEV has rarely been reported. In the present study, phylogenetic…”
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Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization by He, Yong, Li, Kun, Cao, Yimei, Sun, Zixian, Li, Pinghua, Bao, Huifang, Wang, Sheng, Zhu, Guoqiang, Bai, Xingwen, Sun, Pu, Liu, Xuerong, Yang, Cheng, Liu, Zaixin, Lu, Zengjun, Rao, Zihe, Lou, Zhiyong

“…The development of a universal vaccine against foot-and-mouth disease virus (FMDV) is hindered by cross-serotype antigenic diversity and by a lack of knowledge…”
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High-throughput screening unveils nitazoxanide as a potent PRRSV inhibitor by targeting NMRAL1 by Cui, Zhanding, Liu, Jinlong, Xie, Chong, Wang, Tao, Sun, Pu, Wang, Jinlong, Li, Jiaoyang, Li, Guoxiu, Qiu, Jicheng, Zhang, Ying, Li, Dengliang, Sun, Ying, Yin, Juanbin, Li, Kun, Zhao, Zhixun, Yuan, Hong, Bai, Xingwen, Ma, Xueqing, Li, Pinghua, Fu, Yuanfang, Bao, Huifang, Li, Dong, Zhang, Qiang, Liu, Zaixin, Cao, Yimei, Zhang, Jing, Lu, Zengjun

“…Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) poses a major threat to the global swine industry, yet effective prevention and control measures…”
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Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies by Li, Kun, He, Yong, Wang, Li, Li, Pinghua, Bao, Huifang, Huang, Shulun, Zhou, Shasha, Zhu, Guoqiang, Song, Yali, Li, Ying, Wang, Sheng, Zhang, Qianliang, Sun, Pu, Bai, Xingwen, Zhao, Zhixun, Lou, Zhiyong, Cao, Yimei, Lu, Zengjun, Liu, Zaixin

“…Foot-and-mouth disease virus (FMDV) serotype A is antigenically most variable within serotypes. The structures of conserved and variable antigenic sites were…”
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Porcine reproductive and respiratory syndrome virus nonstructural protein 2 promotes the autophagic degradation of adaptor protein SH3KBP1 to antagonize host innate immune responses by enhancing K63-linked polyubiquitination of RIG-I by Li, Jiaoyang, Zhang, Jing, Sun, Pu, Wang, Jian, Li, Guoxiu, Cui, Zhanding, Li, Dong, Yuan, Hong, Wang, Tao, Li, Kun, Bai, Xingwen, Zhao, Zhixun, Cao, Yimei, Ma, Xueqing, Li, Pinghua, Fu, Yuanfang, Bao, Huifang, Liu, Zaixin, Xiao, Shuqi, Wang, Xinglong, Lu, Zengjun

“…Non-structural protein 2 (NSP2) of PRRSV is highly variable and plays crucial roles in the virus's life cycle. To elucidate the function of NSP2 during PRRSV…”
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Engineering viable foot-and-mouth disease viruses with increased acid stability facilitate the development of improved vaccines by Yuan, Hong, Li, Pinghua, Bao, Huifang, Sun, Pu, Bai, Xingwen, Bai, Qifeng, Li, Na, Ma, Xueqing, Cao, Yimei, Fu, Yuanfang, Li, Kun, Zhang, Jing, Li, Dong, Chen, Yingli, Zhang, Jie, Lu, Zengjun, Liu, Zaixin

“…Foot-and-mouth disease virus (FMDV), the most acid-unstable virus among picornaviruses , tends to disassemble into pentamers at pH values slightly below…”
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The long non-coding RNA LNC_000397 negatively regulates PRRSV replication through induction of interferon-stimulated genes by Zhang, Jing, Gan, Lipeng, Sun, Pu, Wang, Jian, Li, Dong, Cao, Yimei, Fu, Yuanfang, Li, Pinghua, Bai, Xingwen, Li, Kun, Ma, Xueqing, Bao, Huifang, Chen, Yingli, Zhang, Jie, Liu, Zaixin, Lu, Zengjun

“…Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant threats to the global swine industry. It is of great importance to…”
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Rational design and efficacy of a multi-epitope recombinant protein vaccine against foot-and-mouth disease virus serotype A in pigs by Cao, Yimei, Li, Dong, Fu, Yuanfang, Bai, Qifeng, Chen, Yingli, Bai, Xingwen, Jing, Zhizhong, Sun, Pu, Bao, Huifang, Li, Pinghua, Zhang, Jing, Ma, Xueqing, Lu, Zengjun, Liu, Zaixin

“…Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, and outbreaks of this disease are often economically catastrophic…”
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Modification of the second translation initiation site restricts the replication of foot-and-mouth disease virus in PK-15 cells by Yuan, Hong, Li, Na, Li, Pinghua, Bai, Xingwen, Sun, Pu, Bao, Huifang, Gong, Xiaohua, Ma, Xueqing, Cao, Yimei, Li, Kun, Fu, Yuanfang, Zhang, Jing, Li, Dong, Chen, Yingli, Zhang, Jie, Lu, Zengjun, Liu, Zaixin

“…The translation initiation of foot-and-mouth disease virus (FMDV) occurs at two alternative initiation sites (Lab AUG and Lb AUG). Usually, the Lb AUG is more…”
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The rescue and selection of thermally stable type O vaccine candidate strains of foot-and-mouth disease virus by Gao, Ya, Li, Pinghua, Ma, Xueqing, Bai, Xingwen, Sun, Pu, Du, Ping, Yuan, Hong, Cao, Yimei, Li, Kun, Fu, Yuanfang, Zhang, Jing, Bao, Huifang, Chen, Yingli, Li, Zhiyong, Lu, Zengjun, Liu, Zaixin, Li, Dong

“…Inactivated foot-and-mouth disease virus (FMDV) vaccines have been used widely to control foot-and-mouth disease (FMD). However, the virions (146S) of this…”
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Evaluation of immunogenicity and cross-reactive responses of  vaccines prepared from two chimeric serotype O foot-and-mouth disease viruses in pigs and cattle by Li, Pinghua, Huang, Shulun, Zha, Jingjing, Sun, Pun, Li, Dong, Bao, Huifang, Cao, Yimei, Bai, Xingwen, Fu, Yuanfang, Ma, Xueqing, Li, Kun, Yuan, Hong, Zhang, Jing, Zhao, Zhixun, Wang, Jian, Zhang, Keqiang, Chen, Yingli, Zhang, Qiang, Qi, Shuyun, Liu, Zaixin, Lu, Zengjun

“…Abstract Foot-and-mouth disease (FMD) remains a very serious barrier to agricultural development and the international trade of animals and animal products…”
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Genome-wide analysis of long noncoding RNA profiling in PRRSV-infected PAM cells by RNA sequencing by Zhang, Jing, Sun, Pu, Gan, Lipeng, Bai, Weijie, Wang, Zhijia, Li, Dong, Cao, Yimei, Fu, Yuanfang, Li, Pinghua, Bai, Xingwen, Ma, Xueqing, Bao, Huifang, Chen, Yingli, Liu, Zaixin, Lu, Zengjun

“…Porcine reproductive and respiratory syndrome (PRRS) is a major threat to the global swine industry and causes tremendous economic losses. Its causative agent,…”
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Development of a Blocking ELISA Using a Monoclonal Antibody to a Dominant Epitope in Non-Structural Protein 3A of Foot-and-Mouth Disease Virus, as a Matching Test for a Negative-Marker Vaccine by Fu, Yuanfang, Li, Pinghua, Cao, Yimei, Wang, Na, Sun, Pu, Shi, Qian, Ji, Xincheng, Bao, Huifang, Li, Dong, Chen, Yingli, Bai, Xingwen, Ma, Xueqing, Zhang, Jing, Lu, Zengjun, Liu, Zaixin

“…Foot-and-mouth disease (FMD) is a devastating animal disease. Strategies for differentiation of infected from vaccinated animals (DIVA) remain very important…”
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Development of Foot-and-Mouth Disease Virus-Neutralizing Monoclonal Antibodies Derived From Plasmablasts of Infected Cattle and Their Germline Gene Usage by Li, Kun, Wang, Sheng, Cao, Yimei, Bao, Huifang, Li, Pinghua, Sun, Pu, Bai, Xingwen, Fu, Yuanfang, Ma, Xueqing, Zhang, Jing, Li, Dong, Chen, Yingli, Liu, Xuerong, An, Fanglan, Wu, Faju, Lu, Zengjun, Liu, Zaixin

“…Cattle are susceptible to foot-and-mouth disease virus (FMDV), and neutralizing antibodies are critical for protection against FMDV infection in this species…”
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The pH stability of foot-and-mouth disease virus by Yuan, Hong, Li, Pinghua, Ma, Xueqing, Lu, Zengjun, Sun, Pu, Bai, Xingwen, Zhang, Jing, Bao, Huifang, Cao, Yimei, Li, Dong, Fu, Yuanfang, Chen, Yingli, Bai, Qifeng, Zhang, Jie, Liu, Zaixin

“…ᅟ: This review summarized the molecular determinants of the acid stability of FMDV in order to explore the uncoating mechanism of FMDV and improve the acid…”
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Development and Evaluation of a Competitive Enzyme-Linked Immunosorbent Assay Based on Swine Monoclonal Antibodies for Detecting Neutralizing Antibodies against Senecavirus A by Ma, Xueqing, Huang, Jiaxin, Li, Kun, Ding, Kailu, Fu, Yuanfang, Zhang, Jing, Zhao, Zhixun, Li, Pinghua, Bai, Xingwen, Li, Dong, Liu, Xia, Zeng, Qiaoying, Liu, Zaixin, Sun, Pu, Lu, Zengjun

“…Senecavirus A (SVA) is an emerging viral pathogen related to vesicular disease and neonatal mortality in swine, which results in enormous economic losses to…”
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Identification of the largest non-essential regions of the C-terminal portion in 3A protein of foot-and-mouth disease virus for replication in cell culture by Li, Pinghua, Ma, Xueqing, Bai, Xingwen, Sun, Pu, Yuan, Hong, Cao, Yimei, Li, Kun, Bao, Huifang, Fu, Yuanfang, Zhang, Jing, Chen, Yingli, Li, Dong, Li, Zhiyong, Lu, Zengjun, Liu, Zaixin

“…Recent study has shown that the C-terminal portion of 3A (amino acids (aa) 81-153) is not essential for foot-and-mouth disease virus replication in cell…”
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Poly(I:C) combined with multi-epitope protein vaccine completely protects against virulent foot-and-mouth disease virus challenge in pigs by Cao, Yimei, Lu, Zengjun, Li, Yanli, Sun, Pu, Li, Dong, Li, Pinghua, Bai, Xingwen, Fu, Yuanfang, Bao, Huifang, Zhou, Chunxue, Xie, Baoxia, Chen, Yingli, Liu, Zaixin

“…► Developing a multi-epitope vaccine for FMD with optimal immunogenicity. ► Combination poly(I:C) with this vaccine conferred 100% protection in pigs. ►…”
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The Identification and Distribution of Cattle XCR1 and XCL1 among Peripheral Blood Cells: New Insights into the Design of Dendritic Cells Targeted Veterinary Vaccine by Li, Kun, Wei, Guoyan, Cao, Yimei, Li, Dong, Li, Pinghua, Zhang, Jing, Bao, Huifang, Chen, Yingli, Fu, Yuanfang, Sun, Pu, Bai, Xingwen, Ma, Xueqing, Lu, Zengjun, Liu, Zaixin

“…The chemokine (C motif) receptor 1 (XCR1) and its ligandXCL1 have been intensively studied in the mouse and human immune systems. Here, we determined the…”
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Development of a blocking ELISA based on a monoclonal antibody against a predominant epitope in non-structural protein 3B2 of foot-and-mouth disease virus for differentiating infected from vaccinated animals by Fu, Yuanfang, Lu, Zengjun, Li, Pinghua, Cao, Yimei, Sun, Pu, Tian, Meina, Wang, Na, Bao, Huifang, Bai, Xingwen, Li, Dong, Chen, Yingli, Liu, Zaixin

“…A monoclonal antibody (McAb) against non-structural protein (NSP) 3B of foot-mouth-disease virus (FMDV) (3B4B1) was generated and shown to recognize a…”
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