Search Results - "Bai, Jiaxiang"
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Engineering immunomodulatory and osteoinductive implant surfaces via mussel adhesion-mediated ion coordination and molecular clicking
Published in Nature communications (10-01-2022)“…Immune response and new tissue formation are important aspects of tissue repair. However, only a single aspect is generally considered in previous biomedical…”
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Exosomes derived from miR-155-5p–overexpressing synovial mesenchymal stem cells prevent osteoarthritis via enhancing proliferation and migration, attenuating apoptosis, and modulating extracellular matrix secretion in chondrocytes
Published in Cell biology and toxicology (01-02-2021)“…Synovial mesenchymal stem cells (SMSCs) have the potential to attenuate osteoarthritis (OA)-induced injury. The role and mechanism of SMSC-derived exosomes…”
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3
Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway
Published in Science China. Life sciences (01-03-2022)“…Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to disability. Inflammatory cell infiltration, severe joint breaking and…”
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Recent advances in responsive hydrogels for diabetic wound healing
Published in Materials today bio (01-02-2023)“…Poor wound healing after diabetes mellitus remains a challenging problem, and its pathophysiological mechanisms have not yet been fully elucidated. Persistent…”
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Recent advances in orthopedic polyetheretherketone biomaterials: Material fabrication and biofunction establishment
Published in Smart materials in medicine (2022)“…Polyetheretherketone (PEEK) is a kind of nontoxic high-performance thermoplastic widely used for medical applications. Compared with other special engineering…”
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Correction: GLI1 facilitates collagen-induced arthritis in mice by collaborative regulation of DNA methyltransferases
Published in eLife (28-03-2024)Get full text
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Rational integration of defense and repair synergy on PEEK osteoimplants via biomimetic peptide clicking strategy
Published in Bioactive materials (01-02-2022)“…Polyetheretherketone (PEEK) has been widely used as orthopedic and dental materials due to excellent mechanical and physicochemical tolerance. However, its…”
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GLI1 facilitates collagen-induced arthritis in mice by collaborative regulation of DNA methyltransferases
Published in eLife (06-11-2023)“…Rheumatoid arthritis (RA) is characterized by joint synovitis and bone destruction, the etiology of which remains to be explored. Many types of cells are…”
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A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions
Published in Bioactive materials (01-08-2022)“…Polyetheretherketone (PEEK) is a desirable alternative to conventional biomedical metals for orthopedic implants due to the excellent mechanical properties…”
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The obesity challenge in joint replacement: a multifaceted analysis of self-reported health status and exercise capacity using NHANES data - a population-based study
Published in International journal of surgery (London, England) (18-03-2024)“…Joint replacement is successful for end-stage osteopathy, with obesity linked to evaluated risk. But the impact of obesity on self-reported health and exercise…”
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Comprehensive overview of microRNA function in rheumatoid arthritis
Published in Bone Research (24-01-2023)“…MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have emerged as vital epigenetic regulators of both pathological and…”
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Alternative Copper-Based Single-Atom Nanozyme with Superior Multienzyme Activities and NIR-II Responsiveness to Fight against Deep Tissue Infections
Published in Research (Washington) (2023)“…Nanozymes are considered to represent a new era of antibacterial agents, while their antibacterial efficiency is limited by the increasing tissue depth of…”
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Targeting strategies for bone diseases: signaling pathways and clinical studies
Published in Signal transduction and targeted therapy (17-05-2023)“…Since the proposal of Paul Ehrlich’s magic bullet concept over 100 years ago, tremendous advances have occurred in targeted therapy. From the initial selective…”
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Cannabinoid Receptor 2 Agonist Prevents Local and Systemic Inflammatory Bone Destruction in Rheumatoid Arthritis
Published in Journal of bone and mineral research (01-04-2019)“…ABSTRACT Cannabinoid receptor 2 (CB2) has been implicated as an important clinical regulator of inflammation and malignant osteolysis. Here, we observed that…”
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Nanomaterial-assisted theranosis of bone diseases
Published in Bioactive materials (01-06-2023)“…Bone-related diseases refer to a group of skeletal disorders that are characterized by bone and cartilage destruction. Conventional approaches can regulate…”
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The protective effects of lixisenatide against inflammatory response in human rheumatoid arthritis fibroblast-like synoviocytes
Published in International immunopharmacology (01-10-2019)“…Rheumatoid arthritis (RA) is a major debilitating systemic disease characterized by chronic inflammation of the synovium and joint destruction. Despite major…”
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A selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice
Published in Biomedicine & pharmacotherapy (01-08-2019)“…[Display omitted] Rheumatoid arthritis (RA) is a chronic, inflammatory, synovitis-dominated systemic disease with unknown etiology. RA is characterized by the…”
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Immunomodulatory biomaterials for implant-associated infections: from conventional to advanced therapeutic strategies
Published in Biomaterials research (05-12-2022)“…Implant-associated infection (IAI) is increasingly emerging as a serious threat with the massive application of biomaterials. Bacteria attached to the surface…”
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Horizon of exosome-mediated bone tissue regeneration: The all-rounder role in biomaterial engineering
Published in Materials today bio (01-12-2022)“…Bone injury repair has always been a tricky problem in clinic, the recent emergence of bone tissue engineering provides a new direction for the repair of bone…”
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How to Perform Better on Oxford UKA? A Technical Note from over 500 Surgical Experiences
Published in Orthopaedic surgery (01-09-2023)“…Oxford unicompartmental knee arthroplasty (UKA) has been particularly prevalent because the concept of knee preservation is deeply rooted in people's minds…”
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