Search Results - "Bai, D. L"
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X-ray Structures of Torpedo californica Acetylcholinesterase Complexed with (+)-Huperzine A and (−)-Huperzine B: Structural Evidence for an Active Site Rearrangement
Published in Biochemistry (Easton) (03-09-2002)“…Kinetic and structural data are presented on the interaction with Torpedo californica acetylcholinesterase (TcAChE) of (+)-huperzine A, a synthetic enantiomer…”
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Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease
Published in Current medicinal chemistry (01-03-2000)“…HupA is a potent, reversible and selective inhibitor of AChE with a rapid absorption and penetration into the brain in animal tests. It exhibits…”
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Perception-action coupling in the development of visual control of posture
Published in Journal of experimental psychology. Human perception and performance (01-12-1997)“…In this investigation of developmental changes in the coordination of perceived optical flow and postural responses, 4 age groups of infants (5-, 7-, 9-, and…”
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Locomotor Status and the Development of Spatial Search Skills
Published in Child development (01-02-1992)“…The principal objective of this experiment was to investigate whether previous reports of a relation between locomotor status and stage 4 object permanence…”
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Similar potency of the enantiomers of huperzine A in inhibition of [ 3H]dizocilpine (MK-801) binding in rat cerebral cortex
Published in Neuroscience letters (08-12-2000)“…The inhibition of huperzine A, a potential therapeutic agent to treat Alzheimer's disease, on rat cortical acetylcholinesterase was found to be highly…”
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Traditional Chinese materia medica--a retrospect and prospect
Published in Memórias do Instituto Oswaldo Cruz (1991)“…For thousands of years, traditional medicine and remedies have been practiced and used in the fight against disease in China. They have proved to be valuable…”
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Infants' Sensitivity to Optical Flow for Controlling Posture
Published in Developmental psychology (01-11-1989)“…Infants' sensitivity to optical flow for controlling sitting and standing was tested using a "moving room" in which all of the walls moved together, or only…”
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Novel Linear Quadrupole Ion Trap/FT Mass Spectrometer: Performance Characterization and Use in the Comparative Analysis of Histone H3 Post-translational Modifications
Published in Journal of proteome research (01-05-2004)“…We describe the design and performance of a prototype high performance hybrid mass spectrometer. This instrument consists of a linear quadrupole ion trap (QLT)…”
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A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia
Published in Development (Cambridge) (01-10-2005)“…Oculodentodigital dysplasia (ODDD) is an autosomal dominant disorder characterized by pleiotropic developmental anomalies of the limbs, teeth, face and eyes…”
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Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons
Published in Molecular pharmacology (01-04-2001)“…gamma-Aminobutyric acid (GABA), the principal inhibitory neurotransmitter, activates a persistent low amplitude tonic current in several brain regions in…”
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Progress in clinical, pharmacological, chemical and structural biological studies of huperzine A: a drug of traditional chinese medicine origin for the treatment of Alzheimer's disease
Published in Current medicinal chemistry (01-11-2003)“…HupA is a potent, reversible AChEI, which crosses the blood-brain barrier smoothly, and shows high specificity for AChE with a prolonged biological half-life…”
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The general anesthetic propofol slows deactivation and desensitization of GABA(A) receptors
Published in The Journal of neuroscience (15-12-1999)“…Propofol (2,6-di-isopropylphenol) has multiple actions on GABA(A) receptor function that act in concert to potentiate GABA-evoked currents. To understand how…”
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Regulation of T Cell Activation, Anxiety, and Male Aggression by RGS2
Published in Proceedings of the National Academy of Sciences - PNAS (24-10-2000)“…Regulators of G protein signaling (RGS) proteins accelerate the GTPase activity of Gα protein subunits in vitro, negatively regulating G protein-coupled…”
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Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A
Published in Biochemical and biophysical research communications (27-08-2004)“…Severe acute respiratory syndrome coronavirus (SARS-CoV) is responsible for SARS infection. Nucleocapsid protein (NP) of SARS-CoV (SARS_NP) functions in…”
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Patch-clamp study reveals that the importance of connexin43-mediated gap junctional communication for ovarian folliculogenesis is strain specific in the mouse
Published in American Journal of Physiology: Cell Physiology (01-01-2006)“…Genetic ablation of connexin37 (Cx37) or connexin43 (Cx43), the two gap junction proteins expressed by mouse ovarian granulosa cells, has been shown to result…”
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Some compounds with 1-adamantyl in place of isopropyl in beta-adrenergic blocking agents (author's transl)
Published in Yao hsüeh hsüeh pao (01-12-1981)Get more information
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Synthesis of some compounds related to tanshinquinone
Published in Yao hsüeh hsüeh pao (01-01-1985)Get more information
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Effects of synthetic (-)-huperzine A on cholinesterase activities and mouse water maze performance
Published in Zhōngguó yàolĭ xuébào (01-09-1998)“…To compare the effects of synthetic and natural (-)-huperzine A (Hup A) on cholinesterase and mouse water maze performance. Spectrophotometry was used to…”
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Novel cyclophilin D inhibitors derived from quinoxaline exhibit highly inhibitory activity against rat mitochondrial swelling and Ca2+ uptake/release
Published in Acta pharmacologica Sinica (01-10-2005)“…Aim: To investigate methods for identifying specific cyclophilin D (CypD) inhibitors derived from quinoxaline, thus developing possible lead compounds to…”
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