Search Results - "Bahrami, Afsane"
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1
Role of the NLRP3 inflammasome in cancer
Published in Molecular cancer (17-11-2018)“…Inflammasomes are large intracellular multi-protein signalling complexes that are formed in the cytosolic compartment as an inflammatory immune response to…”
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2
Counteracting arsenic toxicity: Curcumin to the rescue?
Published in Journal of hazardous materials (05-12-2020)“…[Display omitted] •Arsenicosis leads to various irreversible damages.•Arsenic toxicity is mediated by oxidative stress as well as DNA and protein…”
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3
The prognostic value of MGMT promoter methylation in glioblastoma: A meta‐analysis of clinical trials
Published in Journal of cellular physiology (01-01-2018)“…The DNA repair protein O6‐Methylguanine‐DNA methyltransferase (MGMT) is suggested to be associated with resistance to alkylating agents such as Temozolomide…”
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4
Effect of statins on toll-like receptors: a new insight to pleiotropic effects
Published in Pharmacological research (01-09-2018)“…The toll-like receptors (TLRs) are a class of transmembrane-spanning receptors that are sentinels of both innate and adaptive immunity. Statins…”
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5
Role of adenomatous polyposis coli (APC) gene mutations in the pathogenesis of colorectal cancer; current status and perspectives
Published in Biochimie (01-02-2019)“…Colorectal cancer (CRC) is one of the most common forms of solid tumors in the world with high rates of mortality and morbidity. Most cases of CRCs are…”
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6
Phytosomal curcumin inhibits tumor growth in colitis‐associated colorectal cancer
Published in Journal of cellular physiology (01-10-2018)“…Colorectal‐cancer (CRC) is the third leading cause of death due to cancer, supporting the need for identification of novel anticancer drug to improve the…”
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The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy
Published in Journal of cellular biochemistry (01-12-2017)“…ABSTRACT Cervical cancer is a common gynecological cancer and a leading cause of cancer‐related death in women globally. There is a need for the identification…”
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8
The Role of Interleukin-18 in the Development and Progression of Atherosclerosis
Published in Current medicinal chemistry (01-01-2021)“…Atherosclerosis (AS), as a chronic inflammatory disorder of the cardiovascular system, is one of the leading causes of ischemic heart disease, stroke and…”
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9
Effects of Curcumin on Aging: Molecular Mechanisms and Experimental Evidence
Published in BioMed research international (2021)“…Aging is characterized by a progressive inability to maintain homeostasis, self-repair, renewal, performance, and fitness of different tissues throughout the…”
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10
Therapeutic Potential of Targeting PI3K/AKT Pathway in Treatment of Colorectal Cancer: Rational and Progress
Published in Journal of cellular biochemistry (01-03-2018)“…ABSTRACT PI3K/AKT/mTOR signaling pathway is one of the key dysregulated pathways in different tumor types, including colorectal cancer (CRC). Activation of…”
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11
The dual role of microRNA-9 in gastrointestinal cancers: oncomiR or tumor suppressor?
Published in Biomedicine & pharmacotherapy (01-01-2022)“…microRNA are noncoding endogenous RNAs of ∼ 25-nucleotide, involved in RNA silencing and controlling of cell function. Recent evidence has highlighted the…”
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The role of TFEB in tumor cell autophagy: Diagnostic and therapeutic opportunities
Published in Life sciences (1973) (01-03-2020)“…Autophagy is a conserved “self-eating” recycling process which removes aggregated or misfolded proteins, or defective organelles, to maintain cellular…”
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13
Exosomes: Emerging modulators of signal transduction in colorectal cancer from molecular understanding to clinical application
Published in Biomedicine & pharmacotherapy (01-09-2021)“…Exosomes are small cell derived membrane nano-vesicles that carry various components including lipids, proteins and nucleic acids. There is accumulating…”
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14
Emerging roles for high‐density lipoproteins in neurodegenerative disorders
Published in BioFactors (Oxford) (01-09-2019)“…Lipoproteins are the complexes of different lipids and proteins, which are devoted to the transport and clearance of lipids or lipid‐related molecules in the…”
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15
Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer
Published in Journal of cellular physiology (01-03-2018)“…The V‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) is frequently dysregulated in colorectal cancer (CRC). It is involved in the modulation of…”
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16
Association of healthy eating index (HEI), alternative healthy eating index (AHEI) with antioxidant capacity of maternal breast milk and infant’s urine: a cross-sectional study
Published in Scientific reports (14-10-2024)“…Maternal dietary quality may alter the nutrient content of breast milk. In this study, we aimed to investigate the relationship between the healthy eating…”
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Clinical Significance and Prognosis Value of Wnt Signaling Pathway in Cervical Cancer
Published in Journal of cellular biochemistry (01-10-2017)“…ABSTRACT Cervical cancer is among the most commonly diagnosed cancer in women, supporting the need for identification of novel prognostic and predictive…”
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18
High Dose Supplementation of Vitamin D Affects Measures of Systemic Inflammation: Reductions in High Sensitivity C‐Reactive Protein Level and Neutrophil to Lymphocyte Ratio (NLR) Distribution
Published in Journal of cellular biochemistry (01-12-2017)“…ABSTRACT The prevalence of Vitamin D deficiency is increasing worldwide, which has be shown to be associated with increased risk of cardiovascular disease…”
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Evaluation of the knowledge regarding vitamin D, and sunscreen use of female adolescents in Iran
Published in BMC public health (10-11-2021)“…Vitamin D (Vit D) deficiency/insufficiency is an important risk factor for several chronic conditions. We aimed to evaluate the knowledge and behavior of…”
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A Mediterranean diet is associated with improved total antioxidant content of human breast milk and infant urine
Published in Nutrition journal (23-02-2023)“…The composition of breast milk (BM) is dynamic and can be influenced by maternal variables that include the diet and nutritional status. This study examined…”
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